10026 Results for "

Endogenous

" in MedChemExpress (MCE) Product Catalog:
Products (10026)

10026 Results for "Endogenous" in MCE Product Catalog:

10
10 Cited Publications
Cat. No.: HY-P0202A
CAS No.: 394693-38-0
Synonyms: ET-1 (swine, human) TFA
Target:  

Endothelin Receptor

Research Areas:  

Cardiovascular Disease

Endothelin 1 (swine, human) (ET-1) TFA is a synthetic peptide with the sequence of human and swine Endothelin 1, which is a potent endogenous vasoconstrictor. Endothelin 1 TFA acts through two types of receptors ETA and ETB .
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10
10 Cited Publications
Cat. No.: HY-P1944A
Apelin-13 TFA is an endogenous ligand for the G-protein coupled receptor angiotensin II protein J (APJ), activating this G protein-coupled receptor with an EC 50 value of 0.37 nM. Apelin-13 TFA has vasodilatory and antihypertensive effects. Apelin-13 TFA also can be used for researching type 2 diabetes and metabolic syndrome .
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10
10 Cited Publications
Cat. No.: HY-P1944
CAS No.: 217082-58-1
Apelin-13 is an endogenous ligand for the G-protein coupled receptor angiotensin II protein J (APJ), activating this G protein-coupled receptor with an EC 50 value of 0.37 nM. Apelin-13 is widely distributed in the central and peripheral nervous systems. Apelin-13 has vasodilatory and antihypertensive effects. Apelin-13 also can be used for researching type 2 diabetes and metabolic syndrome .
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9
9 Cited Publications
Cat. No.: HY-19317
CAS No.: 448906-42-1
Research Areas:  

Inflammation/Immunology Cancer

ITE is a potent endogenous agonist of aryl hydrocarbon receptor (AhR), binding directly to AHR, with a Ki of 3 nM. ITE also has immunosuppressive activity.
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8
8 Cited Publications
Cat. No.: HY-W018512
CAS No.: 4651-67-6
Synonyms: 3α-Hydroxy-7-oxo-5β-cholanic acid
7-Ketolithocholic acid (3α-Hydroxy-7-oxo-5β-cholanic acid), a bile acid, can be absorbed and suppresses endogenous bile acid production and biliary cholesterol secretion .
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8
8 Cited Publications
Cat. No.: HY-D0720
CAS No.: 2315-97-1
Synonyms: NSC-151912; L-6868
Lucigenin is a chemiluminescence probe. Lucigenin can be used to detect the production of endogenous superoxide anion radical (O 2-). Lucigenin is extremely sensitive to chloride ions, while it combined with chloride ions, the fluorescence will be quenched. Lucigenin also can be used as a chloride indicator. Ex/Em=455/505 nm .
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8
8 Cited Publications
Cat. No.: HY-Y1362
CAS No.: 617-35-6
Ethyl pyruvate is a simple derivative of the endogenous metabolite pyruvate. Ethyl pyruvate is an HMGB1 release inhibitor. Ethyl pyruvate can induce apoptosis by autophagy. Ethyl pyruvate has anti-inflammatory, antioxidant and anti-tumor activity. Ethyl pyruvate can be used in the study of neurodegenerative diseases such as Alzheimer's and Parkinson's disease .
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7
7 Cited Publications
Cat. No.: HY-116429
CAS No.: 1268720-28-0
Purity:  99.00%
Research Areas:  

Inflammation/Immunology

Maresin 1, produced by human Mφs from endogenous docosahexaenoic acid (DHA) and a specialized proresolving mediator, stimulates intracellular [Ca 2+] and secretion. Maresin 1 possesses anti-inflammatory activity .
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7
7 Cited Publications
Cat. No.: HY-B0234
CAS No.: 53-16-7
Synonyms: E1; Oestrone
Estrone (E1) is a natural estrogenic hormone. Estrone is the main representative of the endogenous estrogens and is produced by several tissues, especially adipose tissue. Estrone is the result of the process of aromatization of androstenedione that occurs in fat cells .
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7
7 Cited Publications
Cat. No.: HY-100236
CAS No.: 374913-63-0
Purity:  99.17%
Synonyms: DDD00107587
Target:  

DNA/RNA Synthesis

Research Areas:  

Cancer

Madrasin (DDD00107587) is a splicing inhibitor that prevents formation of both splicing intermediates and products in vitro and interferes with one or more early steps in the pathway of spliceosome assembly. Madrasin also can inhibit pre-mRNA splicing in vitro and modify splicing of endogenous pre-mRNA in cells .
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7
7 Cited Publications
Cat. No.: HY-100807
CAS No.: 89-00-9
Purity:  99.85%
Quinolinic acid, an endogenous metabolite of tryptophan, is a N-methyl-D-aspartate receptor (NMDA receptor) agonist. Quinolinic acid increases glutamate efflux, induces the generation of ROS, activates nitric oxide synthase, produces excessive NO, leading to calcium ion influx and neuronal apoptosis .
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6
6 Cited Publications
Cat. No.: HY-W010388
CAS No.: 57-00-1
Creatine, an endogenous amino acid derivative, plays an important role in cellular energy, especially in muscle and brain.
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6
6 Cited Publications
Cat. No.: HY-W017462
CAS No.: 6020-87-7
Creatine monohydrate, an endogenous amino acid derivative, plays an important role in cellular energy, especially in muscle and brain .
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6
6 Cited Publications
Cat. No.: HY-P1033
CAS No.: 217082-60-5
Synonyms: [pGlu1]-Apelin-13
Target:  

Apelin Receptor (APJ)

Research Areas:  

Cardiovascular Disease

[Pyr1]-Apelin-13 is a highly potent, selective endogenous apelin receptor (APJ) agonist.
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6
6 Cited Publications
Cat. No.: HY-135103
CAS No.: 145022-92-0
Purity:  98.60%
Synonyms: T-βMCA sodium
Target:  

FXR

Research Areas:  

Cancer

Tauro-β-muricholic Acid sodium (T-βMCA sodium), a endogenous metabolite, is a competitive and reversible farnesoid X receptor (FXR) antagonist, with an IC50 of 40 μM .
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6
6 Cited Publications
Cat. No.: HY-B0360
CAS No.: 90098-04-7
Synonyms: OPC12759; Proamipide
Target:  

COX

Research Areas:  

Inflammation/Immunology Cancer

Rebamipide (OPC12759) is an orally active gastroprotective agent that enhances the production of endogenous PGs (especially intragastric PGE2) by inducing COX-2 expression, thereby protecting the gastric mucosa from injury. Rebamipide exerts anti-proliferative activity against gastric cancer cells. Rebamipide can be used in studies of mucosal protection, gastroduodenal ulcer, gastritis and gastric cancer .
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5
5 Cited Publications
Cat. No.: HY-P0183
CAS No.: 170713-75-4
Synonyms: Orphanin FQ
Target:  

Opioid Receptor

Research Areas:  

Neurological Disease

Nociceptin, a heptadecapeptide, is the endogenous ligand of the nociceptin receptor, acting as a potent anti-analgesic.
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5
5 Cited Publications
Cat. No.: HY-113216
CAS No.: 30315-93-6
Purity:  ≥98.0%
Synonyms: NG,NG-Dimethylarginine
Asymmetric dimethylarginine is an endogenous inhibitor of nitric oxide synthase (NOS), and functions as a marker of endothelial dysfunction in a number of pathological states.
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5
5 Cited Publications
Cat. No.: HY-B0739
CAS No.: 987-78-0
Synonyms: Cytidine diphosphate-choline; CDP-Choline; Cytidine 5'-diphosphocholine
Citicoline is an endogenous intermediate in the synthesis of phosphatidylcholine which is a component of cell membranes. Citicoline inhibits reactive oxygen species (ROS) and apoptosis. Citicoline can be used for neurological disease and hearing loss study .
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5
5 Cited Publications
Cat. No.: HY-B0739A
CAS No.: 33818-15-4
Synonyms: Cytidine diphosphate-choline sodium; CDP-Choline sodium; Cytidine 5'-diphosphocholine sodium
Citicoline sodium is an endogenous intermediate in the synthesis of phosphatidylcholine which is a component of cell membranes. Citicoline sodium inhibits reactive oxygen species (ROS) and apoptosis. Citicoline sodium can be used for neurological disease and hearing loss study .
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