76 Results for "

Antioxidation

" in MedChemExpress (MCE) Product Catalog:
Products (76)

76 Results for "Antioxidation" in MCE Product Catalog:

15
Neobavaisoflavone
Neobavaisoflavone
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15 Publications Verification
Cat. No.: HY-N0720
CAS No.: 41060-15-5
Category:  

Flavonoids Leguminosae Phenols Polyphenols Psoralea corylifolia L. Plants Disease Research Fields Cancer Isoflavones

Target:  

Apoptosis DNA/RNA Synthesis

Neobavaisoflavone, a flavonoid, is isolated from the seeds of Psoralea corylifolia. Neobavaisoflavone exhibits anti-inflammatory, anti-cancer and anti-oxidation activities. Neobavaisoflavone inhibits DNA polymerase at moderate to high concentrations. Neobavaisoflavone also inhibits platelet aggregation .
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14
[6]-Gingerol
[6]-Gingerol
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14 Cited Publications
Cat. No.: HY-14615
CAS No.: 23513-14-6
Purity:  99.68%
Synonyms: (S)-(+)-[6]Gingerol
Category:  

Zingiber officinale Roscoe Monophenols Phenols Plants Disease Research Fields Cancer Zingiberaceae

Target:  

AMPK Apoptosis

[6]-Gingerol is an active compound isolated from Ginger (Zingiber officinale), exhibits a variety of biological activities including anticancer, anti-inflammation, and anti-oxidation.
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13
Shogaol
Shogaol
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13 Cited Publications
Cat. No.: HY-14616
CAS No.: 555-66-8
Purity:  99.63%
Synonyms: [6]-Shogaol; 6-Shogaol
Category:  

Zingiber officinale Roscoe Monophenols Phenols Plants Disease Research Fields Cancer Zingiberaceae

Target:  

Autophagy

Shogaol ([6]-Shogaol), an active compound isolated from Ginger (Zingiber officinale Rosc), exhibits a variety of biological activities including anticancer, anti-inflammation, and anti-oxidation.
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10
Palmatine chloride
Palmatine chloride
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10 Cited Publications
Cat. No.: HY-N0110
CAS No.: 10605-02-4
Category:  

Alkaloids Phellodendron amurense Rupr. Rutaceae Plants Disease Research Fields Isoquinoline Alkaloids Cancer

Target:  

mAChR Indoleamine 2,3-Dioxygenase (IDO) Virus Protease Aurora Kinase Apoptosis Bacterial Parasite

Palmatine chloride is an orally active and irreversible indoleamine 2,3-dioxygenase 1 (IDO-1) inhibitor with IC50s of 3 μM and 157μM against HEK 293-hIDO-1 and rhIDO-1, respectively. Palmatine chloride can also inhibit West Nile virus (WNV) NS2B-NS3 protease in an uncompetitive manner with an IC50 of 96 μM. Palmatine chloride shows anti-cancer, anti-oxidation, anti-inflammatory, neuroprotection, antibacterial, anti-viral activities .
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10
Palmatine hydroxide
Palmatine hydroxide
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10 Cited Publications
Cat. No.: HY-N0110B
CAS No.: 131-04-4
Category:  

Alkaloids Phellodendron amurense Rupr. Other Alkaloids Rutaceae Plants

Target:  

mAChR Indoleamine 2,3-Dioxygenase (IDO) Virus Protease Aurora Kinase Apoptosis Bacterial Parasite

Palmatine hydroxide is an orally active and irreversible indoleamine 2,3-dioxygenase 1 (IDO-1) inhibitor with IC50s of 3 μM and 157μM against HEK 293-hIDO-1 and rhIDO-1, respectively. Palmatine hydroxide can also inhibit West Nile virus (WNV) NS2B-NS3 protease in an uncompetitive manner with an IC50 of 96 μM. Palmatine hydroxide shows anti-cancer, anti-oxidation, anti-inflammatory, neuroprotection, antibacterial, anti-viral activities .
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8
Danshensu
Danshensu
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8 Cited Publications
Cat. No.: HY-N1913
CAS No.: 76822-21-4
Synonyms: Dan shen suan A; Salvianic acid A
Category:  

Simple Phenylpropanols Labiatae Samanea saman (Jacq.) Merr. Phenols Polyphenols Phenylpropanoids Plants Disease Research Fields Cancer

Target:  

Keap1-Nrf2 NF-κB Reactive Oxygen Species (ROS) SARS-CoV Apoptosis

Danshensu (Dan shen suan A), an orally active phenolic compound, can induce Nrf2/HO-1 activation and inhibition of NF-κB pathway. Danshensu reduces reactive oxygen species (ROS) production, upregulates antioxidant defense mechanism and inhibits intrinsic apoptotic pathway. Danshensu displays a potent antiviral activity against SARS-CoV-2 with EC50 of 0.97 μM. Danshensu has anti-oxidation, anti-apoptosis, anti-lung inflammatory and has the potential for COVID-19, cardiovascular and cerebrovascular diseases research .
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8
Danshensu sodium
Danshensu sodium
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8 Cited Publications
Cat. No.: HY-N1913A
CAS No.: 81075-52-7
Synonyms: Dan shen suan A sodium; Salvianic acid A sodium
Category:  

Simple Phenylpropanols Labiatae Samanea saman (Jacq.) Merr. Phenols Polyphenols Phenylpropanoids Plants

Target:  

Keap1-Nrf2 NF-κB Reactive Oxygen Species (ROS) SARS-CoV Apoptosis

Danshensu (Dan shen suan A) sodium, an orally active phenolic compound, can induce Nrf2/HO-1 activation and inhibition of NF-κB pathway. Danshensu sodium reduces reactive oxygen species (ROS) production, upregulates antioxidant defense mechanism and inhibits intrinsic apoptotic pathway. Danshensu sodium displays a potent antiviral activity against SARS-CoV-2 with EC50 of 0.97 μM. Danshensu sodium has anti-oxidation, anti-apoptosis, anti-lung inflammatory and has the potential for COVID-19, cardiovascular and cerebrovascular diseases research .
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7
DL-alpha-Tocopherol
DL-alpha-Tocopherol
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7 Cited Publications
Cat. No.: HY-W020044
CAS No.: 10191-41-0
Synonyms: DL-α-Tocopherol
Category:  

Duchesnea indica (Andr.) Focke Monophenols Other Diseases Rosaceae Phenols Plants Disease Research Fields

Target:  

Environmental Pollutants Ferroptosis Apoptosis DNA/RNA Synthesis

DL-alpha-Tocopherol is a synthetic vitamin E, with antioxidation effect. DL-alpha-Tocopherol protects human skin fibroblasts against the cytotoxic effect of UVB .
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7
DL-alpha-Tocopherol (Standard)
DL-alpha-Tocopherol (Standard)
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7 Cited Publications
Cat. No.: HY-W020044R
CAS No.: 10191-41-0
Synonyms: DL-α-Tocopherol (Standard)
Category:  

Duchesnea indica (Andr.) Focke Other Diseases Rosaceae Phenols Plants Disease Research Fields

Target:  

Reference Standards Ferroptosis DNA/RNA Synthesis Apoptosis

DL-alpha-Tocopherol (Standard) is the analytical standard of DL-alpha-Tocopherol. This product is intended for research and analytical applications. DL-alpha-Tocopherol is a synthetic vitamin E, with antioxidation effect. DL-alpha-Tocopherol protects human skin fibroblasts against the cytotoxic effect of UVB .
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6
Creatinine
Creatinine
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6 Cited Publications
Cat. No.: HY-B0504
CAS No.: 60-27-5
Synonyms: NSC13123
Category:  

Infection Natural Products Disease markers Metabolic Disease Endocrine diseases Nervous System Disorder Endogenous metabolite Disease Research Fields

Target:  

Endogenous Metabolite GABA Receptor iGluR

Creatinine (NSC13123) is an orally active, blood-brain barrier-permeable modulator of GABAA and NMDA receptors, with activities of antioxidation and metabolic regulation. Creatinine is generated via non-enzymatic conversion of creatine and phosphocreatine in muscle. Creatinine serum levels correlate with muscle mass, glomerular filtration rate, and extrarenal clearance, serving as an evaluation biomarker for renal function, muscle mass, and clinical outcomes, and used for perioperative renal risk assessment. In addition, Creatinine can induce specific Cryptococcus species to produce creatinine deiminase and act as their nitrogen source, while it can be secreted via renal tubules. Creatinine is widely used in research related to various diseases such as neurodegenerative diseases, psychiatric disorders, acute kidney injury, chronic kidney disease, and renal failure .
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5
Creatinine-d3
Creatinine-d3
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5 Cited Publications
Cat. No.: HY-B0504S
CAS No.: 143827-20-7
Synonyms: NSC13123-d3
Creatinine-d3 is a deuterium labeled Creatinine. Creatinine (NSC13123) is an orally active, blood-brain barrier-permeable modulator of GABAA and NMDA receptors, with activities of antioxidation and metabolic regulation. Creatinine is generated via non-enzymatic conversion of creatine and phosphocreatine in muscle. Creatinine serum levels correlate with muscle mass, glomerular filtration rate, and extrarenal clearance, serving as an evaluation biomarker for renal function, muscle mass, and clinical outcomes, and used for perioperative renal risk assessment. In addition, Creatinine can induce specific Cryptococcus species to produce creatinine deiminase and act as their nitrogen source, while it can be secreted via renal tubules. Creatinine is widely used in research related to various diseases such as neurodegenerative diseases, psychiatric disorders, acute kidney injury, chronic kidney disease, and renal failure .
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4
Notoginsenoside R1
Notoginsenoside R1
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4 Cited Publications
Cat. No.: HY-N0615
CAS No.: 80418-24-2
Synonyms: Sanchinoside R1; Sanqi glucoside R1
Category:  

Triterpenes Panax notoginseng (Burkill) F. H. Chen ex C. H. Chow Terpenoids Other Diseases Plants Disease Research Fields Araliaceae

Target:  

Amyloid-β Apoptosis

Notoginsenoside R1 (Sanchinoside R1), a saponin, is isolated from P. notoginseng. Notoginsenoside R1 exhibits anti-oxidation, anti-inflammatory, anti-angiogenic, and anti-apoptosis activities. Notoginsenoside R1 provides cardioprotection against ischemia/reperfusion (I/R) injury. Notoginsenoside R1 also provides neuroprotection in H2O2-induced oxidative damage in PC12 cells .
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4
Ditiocarb sodium
Ditiocarb sodium
0 Images
4 Cited Publications
Cat. No.: HY-B1637
CAS No.: 148-18-5
Synonyms: Sodium diethyldithiocarbamate
Target:  

HIV Biochemical Assay Reagents

Research Areas:  

Infection Inflammation/Immunology Cancer

Ditiocarb sodium (Sodium diethyldithiocarbamate) is an orally active copper reagent. Ditiocarb sodium exhibits activities such as antioxidation, chelation, anti-tumor effects, immunomodulation, and anti-HIV properties. Ditiocarb sodium can be used in the research of tumors, inflammatory, and immune-related diseases .
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4
Ditiocarb sodium,98%
Ditiocarb sodium,98%
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4 Cited Publications
Cat. No.: HY-B1637A
CAS No.: 148-18-5
Synonyms: Sodium diethyldithiocarbamate,98%
Target:  

HIV Biochemical Assay Reagents

Research Areas:  

Infection Inflammation/Immunology Cancer

Ditiocarb sodium,98% (Sodium diethyldithiocarbamate,98%) is an orally active copper reagent. Ditiocarb sodium,98% exhibits activities such as antioxidation, chelation, anti-tumor effects, immunomodulation, and anti-HIV properties. Ditiocarb sodium,98% can be used in the research of tumors, inflammatory, and immune-related diseases .
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3
Cinnamaldehyde
Cinnamaldehyde
0 Images
3 Cited Publications
Cat. No.: HY-N0609
CAS No.: 104-55-2
Category:  

Natural Products Plants Disease Research Fields Inflammation/Immunology

Target:  

Environmental Pollutants

Cinnamaldehyde is a major and a bioactive compound isolated from the leaves of Cinnamomum osmophloeum kaneh. Cinnamaldehyde is a cytokine production inhibitor. Cinnamaldehyde has anti-bacteria, anti-oxidation, and anti-inflammatory properties .
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1
Hydroxycitric acid
Hydroxycitric acid
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1 Cited Publications
Cat. No.: HY-N1437
CAS No.: 6205-14-7
Category:  

Ketones, Aldehydes, Acids Guttiferae Plants Garcinia gummi-gutta (L.) Roxb.

Target:  

Apoptosis Ferroptosis mTOR DNA/RNA Synthesis Keap1-Nrf2 Ribosomal S6 Kinase (RSK) NF-κB ATP Citrate Lyase AMPK

Hydroxycitric acid is an orally active, multi-target, multi-bioactive organic acid. activates Nrf2 and its downstream molecule GPX4, increases glutathione levels, and thereby inhibits ferroptosis. Hydroxycitric acid activates the Nrf2/Keap1 and ACLY/NF-κB signaling pathways, upregulates the activities of antioxidant enzymes such as superoxide dismutase, reduces MDA content, thereby alleviating oxidative stress and renal tubular epithelial cell apoptosis, and improves pulmonary vascular and right ventricular remodeling. Hydroxycitric acid activates both the AMPK and mTORC1/S6K pathways, triggers the unfolded protein response, arrests the cancer cell cycle, and induces DNA fragmentation .
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1
CAY10594
CAY10594
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1 Cited Publications
Cat. No.: HY-121983
CAS No.: 1130067-34-3
Purity:  98.95%
Target:  

Phospholipase Apoptosis GSK-3 Anaplastic lymphoma kinase (ALK) STAT Interleukin Related G Protein-coupled Receptor Kinase (GRK) CXCR Lactate Dehydrogenase

Research Areas:  

Inflammation/Immunology Cancer

CAY10594 is an orally active PLD2 inhibitor with an IC50 of 140 nM. CAY10594 has activities such as anti-tumor, anti-oxidation and liver protection. CAY10594 can be used for the research of diseases like breast cancer, acute liver injury and colitis .
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1
4-Hydroxyretinoic acid
4-Hydroxyretinoic acid
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1 Cited Publications
Cat. No.: HY-125904
CAS No.: 66592-72-1
Purity:  95.11%
Target:  

RAR/RXR UGT Cytochrome P450 Apoptosis Drug Derivative

Research Areas:  

Neurological Disease Inflammation/Immunology Cancer

4-Hydroxyretinoic acid (4-HRA) is a derivative of Retinoic acid (HY-14649). 4-Hydroxyretinoic acid is formed via the catalysis of retinol by cytochrome P-450 isoenzymes. 4-Hydroxyretinoic acid also serves as a substrate for UDP-glucuronosyltransferase (s) and recombinant UGT2B7. 4-Hydroxyretinoic acid binds to the nuclear receptor RAR (Retinoic Acid Receptor), activates RAR and RXR-alpha, subsequently regulates gene expression and cell differentiation, and induces cancer cell apoptosis (Apoptosis). 4-Hydroxyretinoic acid also participates in multiple physiological processes such as immunoregulation, neuroprotection and antioxidation .
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1
[6]-Gingerol (Standard)
[6]-Gingerol (Standard)
0 Images
1 Cited Publications
Cat. No.: HY-14615R
CAS No.: 23513-14-6
Synonyms: (S)-(+)-[6]Gingerol (Standard)
Category:  

Zingiber officinale Roscoe Monophenols Phenols Plants Zingiberaceae

Target:  

Reference Standards AMPK Apoptosis

-Gingerol (Standard) is the analytical standard of -Gingerol. This product is intended for research and analytical applications. -Gingerol is an active compound isolated from Ginger (Zingiber officinale), exhibits a variety of biological activities including anticancer, anti-inflammation, and anti-oxidation.
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1
Soyasaponin Ab
Soyasaponin Ab
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1 Cited Publications
Cat. No.: HY-N3026
CAS No.: 118194-13-1
Category:  

Triterpenes Leguminosae Glycine max (L.) merr Terpenoids Metabolic Disease Plants Disease Research Fields

Target:  

PPAR Apoptosis Reactive Oxygen Species (ROS)

Soyasaponin Ab is an orally active soyasaponin. Soyasaponin Ab inhibits PPARγ transcriptional activity. Soyasaponin Ab induces apoptosis in high concentrations. Soyasaponin Ab exerts anti-obesity, anti-oxidation, anti-inflammation, anti-aging effects. Soyasaponin Ab prevents Scopolamine (HY-N0296)-induced memory impairment .
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