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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
1075 Results for "
Compound E
" in MedChemExpress (MCE) Product Catalog:
Products (1075)
1075 Results for "Compound E" in MCE Product Catalog:
18
18 Publications Verification
Synonyms: γ-Secretase-IN-1
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Compound E is a γ-secretase inhibitor. Compound E blocks β-amyloid(40), β-amyloid(42), and Notch γ-secretase cleavage with IC50s of 0.24, 0.37, 0.32 nM, respectively.
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6 Cited Publications
Synonyms: 17-Hydroxy-11-dehydrocorticosterone; Kendall's Compound E
4
4 Cited Publications
Cat. No.: HY-N4182
CAS No.: 864232-34-8
4
Category:
Phenols Polyphenols Amburana cearensis (Allemão) A.C.Sm. Plants Compositae Disease Research Fields Inflammation/Immunology Cancer
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3
3 Cited Publications
Cat. No.: HY-N2963
CAS No.: 90902-21-9
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ERK p38 MAPK JAK STAT TNF Receptor Interleukin Related COX Arginase
3
3
3 Cited Publications
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LONP1-IN-2 (Compound 9e) is a potent and selective LONP1 inhibitor with an IC50 value of 0.093 μM. LONP1-IN-2 can be used in research of cancer .
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2 Cited Publications
Synonyms: U-42585E free acid
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Lodoxamide (U-42585E free acid) is an antiallergic compound acting as a mast-cell stabilizer for the treatment of asthma and allergic conjunctivitis.
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2 Cited Publications
PROTAC K-Ras Degrader-1 (Compound 518) is a PROTAC. PROTAC K-Ras Degrader-1 can effectively degrades K-Ras based on Cereblon E3 ligand, exhibits ≥70% degradation efficacy in SW1573 cells .
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2 Cited Publications
Cat. No.: HY-N6954
CAS No.: 76996-27-5
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1
1 Cited Publications
Cat. No.: HY-N2173
CAS No.: 93675-88-8
Category:
Oleaceae Simple Phenylpropanols Phenols Polyphenols Phenylpropanoids Plants Forsythia suspensa (Thunb.) Vahl Disease Research Fields Inflammation/Immunology
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1
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U-83836E (PNU-83836E) is a compound with anti-inflammatory and antioxidant activities that reduces lung inflammation inhibiting oxidative stress and ROS production. U-83836E has shown potential for studying asthma and lung inflammation in animal models .
1
1 Cited Publications
Synonyms: (E/Z)-Tyrphostin AG490; (E/Z)-Tyrphostin B42
(E/Z)-AG490 ((E/Z)-Tyrphostin AG490) is a racemic compound of (E)-AG490 and (Z)-AG490 isomers. (E)-AG490 (HY-12000) is a tyrosine kinase inhibitor that inhibits EGFR, Stat-3 and JAK2/3.
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1
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Cedazuridine (E7727) (Compound 7a) is an orally active cytidine deaminase (CDA) inhibitor with an IC50 value of 0.4 μM. Cedazuridine can be used for cancer research .
1
1 Cited Publications
LtaS-IN-1 (compound 1771) is a potent small-molecule inhibitor of Lipoteichoic acid (LTA) synthesis in multidrug-resistant (MDR) E. faecium and by altering the cell wall morphology. LtaS-IN-1 alone inhibits Enterococcus.spp 28 strains with varying MIC values ranging from 0.5 μg/mL to 64 μg/mL. LtaS-IN-1 combination with antibiotics abolishs multidrug-resistant E. faecium growth almost completely .
1
1 Cited Publications
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GSK-3 inhibitor 1 (compound core 3) is a GSK-3 inhibitor that induces stem/progenitor cell self-renewal (e.g. induces stem/progenitor cell proliferation while maintaining the ability to differentiate into tissue cells in the progeny) .
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1 Cited Publications
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CK1-IN-2 (compound Nr.4) is a potent CK1 inhibitor with an IC50 values of 123, 19.8, 26.8, 74.3 nM for CK1a, CK1d, CK1e, p38a, respectively .
1
1 Cited Publications
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PROTAC ERα Degrader-1 comprises an ubiquitin E3 ligase binding group, a linker and a protein binding group. PROTAC ERα Degrader-1 extracts from patent WO2017201449A1, compound P1. PROTAC ERα Degrader-1 is an estrogen receptor-alpha (ERα) degrader.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
