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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
751 Results for "
Cysteines
" in MedChemExpress (MCE) Product Catalog:
Products (751)
751 Results for "Cysteines" in MCE Product Catalog:
803
803 Publications Verification
Synonyms: N-Acetylcysteine; N-Acetyl-L-cysteine; NAC
150
150 Cited Publications
Synonyms: Diferuloylmethane; Natural Yellow 3; Turmeric yellow
138
138 Cited Publications
Target:
Research Areas:
C-176 is a selective and blood-brain barrier permeable STING inhibitor. C-176 covalently targets transmembrane cysteine residue 91 and thereby blocking activation-induced palmitoylation of STING .
99
99 Cited Publications
Synonyms: E64d; E64c ethyl ester
Research Areas:
Aloxistatin (E64d) is a cell-permeable and irreversible broad-spectrum cysteine protease inhibitor. Aloxistatin (E64d) exhibits entry-blocking effect for MERS-CoV.
68
Adagrasib (MRTX849) is a potent, orally-available, and mutation-selective covalent inhibitor of KRAS G12C with potential antineoplastic activity. Adagrasib covalently binds to KRAS G12C at the cysteine at residue 12, locks the protein in its inactive GDP-bound conformation, and inhibits KRAS-dependent signal transduction .
53
Target:
Research Areas:
N-Ethylmaleimide (NEM) derives from maleic acid, it can alkylates free sulfhydryl. N-Ethylmaleimide is an irreversible cysteine protease inhibitor. N-ethylmaleimide specific inhibits phosphate transport in mitochondria. N-Ethylmaleimide inhibits prolyl endopeptidase with an IC50 value of 6.3 μM. N-Ethylmaleimide can be used to modify cysteine residues in proteins and peptides .
36
36 Cited Publications
Synonyms: Dehydroxymethylepoxyquinomicin
Target:
Research Areas:
(-)-DHMEQ (Dehydroxymethylepoxyquinomicin) is a potent, selective and irreversible NF-κB inhibitor that covalently binds to a cysteine residue. (-)-DHMEQ inhibits nuclear translocation of NF-κB and shows anti-inflammatory and anticancer activity .
36
Category:
Infection Acanthaceae Extract Plant Terpenoids Diterpenoids Disease Research Fields Inflammation/Immunology Andrographis paniculata (Burm. F.) Nees Extract
Target:
30
30 Cited Publications
27
27 Cited Publications
Synonyms: Proteinase inhibitor E 64
Research Areas:
E-64 (Proteinase inhibitor E 64) is a potent irreversible inhibitor against general cysteine proteases with IC50 of 9 nM for papain.
27
Target:
Leptomycin B (CI 940; LMB) is a potent inhibitor of the nuclear export of proteins. Leptomycin B inactivates CRM1/exportin 1 by covalent modification at a cysteine residue. Leptomycin B is a potent antifungal antibiotic blocking the eukaryotic cell cycle .
24
Target:
Research Areas:
MitoTracker Deep Red (MTDR) FM fluorescent dye that selectively accumulates in the mitochondrial matrix. MitoTracker Deep Red FM covalently binds mitochondrial proteins by reacting with free mercaptan of cysteine residues. MitoTracker Deep Red dyes have an excitation/emission wavelength of 633/650-750 nm .
The Ex/Em of MitoTracker Deep Red (MTDR) FM is 644/665 nm.
The Ex/Em of MitoTracker Deep Red (MTDR) FM is 644/665 nm.
21
Category:
Human Gut Microbiota Metabolites Disease markers Metabolic Disease Amino acids Nervous System Disorder Microorganism Endogenous metabolite Disease Research Fields
Target:
20
Target:
Research Areas:
MDL-28170 (Calpain Inhibitor III) is a potent, selective and membrane-permeable cysteine protease inhibitor of calpain that rapidly penetrates the blood-brain barrier following systemic administration . MDL-28170 also block γ-secretase .
18
Category:
Caricaceae Extract Natural Products Plant Carica papaya L. Extract Disease Research Fields Inflammation/Immunology
Target:
16
Target:
Research Areas:
2-Iodoacetamide (Iodoacetamide), an alkylating agent, is a commonly used agent for alkylation of cysteine during sample preparation for proteomics .
14
14
Target:
14
14 Cited Publications
Synonyms: N-Acetylcysteine ethyl ester; NACET
Target:
Research Areas:
N-Acetyl-L-cysteine ethyl ester is an esterified form of N-acetyl-L-cysteine (NAC). N-Acetyl-L-cysteine ethyl ester exhibits enhanced cell permeability, and produce NAC and cysteine. N-Acetyl-L-cysteine ethyl ester increases circulating hydrogen sulfide (H2S) and can be used as an H2S producer. N-Acetyl-L-cysteine ethyl ester has the potential to substitute NAC as a mucolytic agent, and as a GSH-related antioxidant .
14
14 Cited Publications
Cat. No.: HY-W016715
CAS No.: 7048-04-6
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
