Search Result
Results for "
DMTS
" in MedChemExpress (MCE) Product Catalog:
10
Biochemical Assay Reagents
16
Isotope-Labeled Compounds
| Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
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- HY-138579
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- HY-45491
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- HY-21997
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- HY-W013068
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- HY-104014
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Phosphoramidites
DNA/RNA Synthesis
Nucleoside Antimetabolite/Analog
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Others
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DMT-2'O-MOE-rG(ib) Phosphoramidite belongs to cyanoethyl-protected nucleoside phosphoramidites. DMT-2'O-MOE-rG(ib) Phosphoramidite is a derivative of nucleotide and guanosine. DMT-2'O-MOE-rG(ib) Phosphoramidite can be used for the stereochemical synthesis of phosphorothioate oligonucleotides .
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- HY-45409
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2'-F-dU Phosphoramidite
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Phosphoramidites
Nucleoside Antimetabolite/Analog
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Cancer
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DMT-2’ Fluoro-dU Phosphoramidite (2'-F-dU Phosphoramidite) is a uridine phosphoramidite with a fluorine in the 2’ position. DMT-2’ Fluoro-dU Phosphoramidite could be used for nucleoside modification and synthesis of DNA .
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- HY-W006102
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- HY-45492
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2'-F-ibu-dG Phosphoramidite
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Phosphoramidites
Nucleoside Antimetabolite/Analog
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Cancer
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DMT-2'Fluoro-DG(IB) Amidite (2'-F-ibu-dG Phosphoramidite) is a nucleoside that can be employed for oligonucleotide synthesis. DMT-2'Fluoro-DG(IB) Amidite can be used to prepare 4'-modified 2'-deoxy-2'-fluorouridine .
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- HY-W101391
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2'-O-Me-U Phosphoramidite
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Phosphoramidites
DNA/RNA Synthesis
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Others
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DMT-2'O-Methyl-rU Phosphoramidite (2'-O-Me-U Phosphoramidite) is a 2'-O-Me derivative, and can be used for oligonucleotide synthesis .
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- HY-B1311
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SKF-525A; U-5446; RP-5171
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Cytochrome P450
Monoamine Oxidase
Bcl-2 Family
Survivin
PARP
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Neurological Disease
Inflammation/Immunology
Cancer
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Proadifen (SKF-525A) hydrochloride is a non-competitive Cytochrome P450 inhibitor with an IC50 value of 19 μM. Proadifen hydrochloride reduces monoamine oxidase A (MAO-A) activity and reverses the antidepressantlike behavioral effect of Imipramine (HY-B1490A) and Desipramine (HY-B1272A) in rats. Proadifen hydrochloride also reduces N, N-dimethyltryptamine (DMT) metabolism in liver microsomes and inhibits N-demethylationand Acridone (HY-W007771) formation. Proadifen hydrochloride augments Lipopolysaccharide (LPS) (HY-D1056)-induced fever and exacerbates Prostaglandin E2 (PGE2) (HY-101952) levels in the rat. Proadifen hydrochloride is promising for research of metabolism-related deseases, ovarian carcinoma, inflammation and dopamine neurons-related deseases .
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- HY-138585
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- HY-104017
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- HY-W013059
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- HY-126301
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Ferroportin
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Metabolic Disease
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DMT1 blocker 1 is an orally active blocker of divalent metal transporter 1 (DMT1) with an IC50 of 0.64 μM. DMT1 blocker 1 inhibits intestinal cell absorption of non-heme iron, thereby alleviating iron overload by blocking the DMT1 transporter. DMT1 blocker 1 demonstrates significant efficacy in rodent models of acute iron hyperabsorption. DMT1 blocker 1 is useful for studying iron overload disorders such as hereditary hemochromatosis and thalassemia .
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- HY-46317
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Phosphoramidites
DNA/RNA Synthesis
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Metabolic Disease
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DMT-5Me-dC(Bz)-CE Phosphoramidite is a chemical structural unit that can be used in solid-phase DNA synthesis. DMT-5Me-dC(Bz)-CE Phosphoramidite can introduce the 5-methylcytidine base into the DNA chain to enhance its stability and binding affinity. DMT-5Me-dC(Bz)-CE Phosphoramidite can be used to construct modified oligonucleotides, especially for constructing locked nucleic acids (LNA) .
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- HY-126302
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Ferroportin
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Metabolic Disease
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DMT1 blocker 2 is a direct inhibitor of divalent metal transporter 1 (DMT1), with an IC50 of 0.83 μM. DMT1 blocker 2 can block iron uptake by enterocytes in vivo .
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- HY-W008849
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- HY-139988
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- HY-W010744
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5'-O-DMT-dI; 2'-Deoxy-5'-O-DMT-inosine
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Phosphoramidites
Nucleoside Antimetabolite/Analog
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Cancer
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DMT-dI (5'-O-DMT-dI) is a deoxyribonucleoside containing a hypoxanthine base. DMT-dI can be used to prepare convertible nucleoside derivatives to prepare modified oligonucleotides complementary to target genes for gene editing. DMT-dI can be used to study various conditions, disorders or diseases modified by adenosine .
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- HY-W093086
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- HY-W115186
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- HY-138601
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- HY-138581
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- HY-49200
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Nucleoside Antimetabolite/Analog
Phosphoramidites
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Cancer
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DMT-2'-F-dC(Bz)-CE-Phosphoramidite is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
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- HY-138606
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- HY-43060
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- HY-W013059S
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DA-CE phosphoramidite-13C10,15N5
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DNA/RNA Synthesis
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Others
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DMT-dA(bz) Phosphoramidite- 13C10, 15N5 is the 13C and 15N labeled DMT-dA(bz) Phosphoramidite . DMT-dA(bz) Phosphoramidite is typically used in the synthesis of DNA .
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- HY-169460
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- HY-W008848S
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- HY-160884
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DNA/RNA Synthesis
Phosphoramidites
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Others
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DMT-2'-OMe-D-Ribitol phosphoramidite (compound 9) is an abasic phosphoramidite monomer that can be used to introduce the abasic group Y34 into oligonucleotides .
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- HY-W061439
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Drug Intermediate
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Cancer
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(3R,5S)-5-O-DMT-3-pyrrolidinol is a compound with a dimethoxytrityl (DMT) protecting group and a 3-pyrrolidinol structure. (3R,5S)-5-O-DMT-3-pyrrolidinol is a key intermediate used in the research of nucleic acid drugs and biological preparations.
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- HY-43058
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- HY-138608
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- HY-164181
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- HY-P5131
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Opioid Receptor
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Others
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[Dmt1]DALDA is a potent and long-acting analgesic binds to the mu opioid receptor with high affinity and selectivity. [Dmt1]DALDA is a full agonist at hMOR (Kd = 0.199 nM) and hDOR, but only partial agonist against hKOR .
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- HY-W115309
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5'-DMT-2'-F-ibu-dG
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Phosphoramidites
Nucleoside Antimetabolite/Analog
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Others
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DMT-2'-F-iBu-G (5'-DMT-2'-F-ibu-dG) is a modified oligonucleotide. 2'-deoxy-2'-fluoro-modified oligonucleotides shows high nuclease resistant and retained exceptional binding affinity to the RNA targets .
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- HY-W013059S2
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DA-CE phosphoramidite-d9
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Isotope-Labeled Compounds
DNA/RNA Synthesis
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Others
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DMT-dA(bz) Phosphoramidite-d9 (DA-CE phosphoramidite-d9) is deuterium labeled DMT-dA(bz) Phosphoramidite (HY-W013059). DMT-dA(bz) Phosphoramidite is typically used in the synthesis of DNA.
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- HY-169785
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7-TMT
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5-HT Receptor
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Neurological Disease
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7-Methyl DMT (7-TMT) is a 5-HT2 receptor agonist. Structurally, 7-Methyl DMT is a tryptamine derivative. It can be used as an analytical reference standard for the psychoactive substance DOM. 7-Methyl DMT is also used in research in the field of neurological diseases .
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- HY-W700549
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- HY-138607
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- HY-154916
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13-DMT; 13-O-Demethyl FK 506
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Drug Derivative
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Infection
Inflammation/Immunology
Cancer
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13-O-Desmethyl tacrolimus (13-DMT; 13-O-Demethyl FK 506) is the main metabolite of Tacrolimus (HY-13756). 13-O-Desmethyl tacrolimus has a weak immunosuppressive activity. 13-O-Desmethyl tacrolimus is mainly used in the research on monitoring Tacrolimus (HY-13756) by monitoring the ratio of 13-DMT/Tacrolimus .
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- HY-W114886
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- HY-W570893
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- HY-138609
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- HY-N11421
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23-DMT; 23-Demycinosyltylosin
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Bacterial
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Infection
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23-O-Demycinosyltylosin (23-DMT) is a 23-O-demycinosyltylosin (DMT) acyl derivative with antibacterial activity .
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- HY-150658S
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- HY-W854187
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- HY-W013068S1
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- HY-W013068S3
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- HY-W013068S2
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- HY-W013059S1
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DA-CE phosphoramidite-15N5
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DNA/RNA Synthesis
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Others
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DMT-dA(bz) Phosphoramidite- 15N5 is the 15N labeled DMT-dA(bz) Phosphoramidite . DMT-dA(bz) Phosphoramidite is typically used in the synthesis of DNA .
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- HY-W036167
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- HY-153249
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- HY-168014
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- HY-W013068S
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- HY-W018179
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- HY-W579407
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- HY-153251
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- HY-153253
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- HY-W579408
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- HY-21713
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- HY-W783407
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- HY-W579410
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- HY-W048489
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5'-O-(4,4'-Dimethoxytrityl)-2'-O-methoxyethyl-thymidine
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Phosphoramidites
Nucleoside Antimetabolite/Analog
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Others
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DMT-2'-O-MOE-Tr (5'-O-(4,4'-Dimethoxytrityl)-2'-O-methoxyethyl-thymidine) is a nucleoside analog containing a dimethoxytrityl (DMT) group, commonly used in the synthesis of nucleic acids.
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- HY-W008848S1
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- HY-W013059R
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DA-CE phosphoramidite (Standard)
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Reference Standards
DNA/RNA Synthesis
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Others
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DMT-dA(bz) Phosphoramidite (Standard) is the analytical standard of DMT-dA(bz) Phosphoramidite. This product is intended for research and analytical applications. DMT-dA(bz) Phosphoramidite is a phosphoramide monomer for the synthesis of oligonucleotides (ONs) through formation of DNA dimers and trimers via mechanochemistry .
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- HY-177197
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- HY-177196
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- HY-145464
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- HY-177198
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- HY-W013059A
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L-DA-CE phosphoramidite
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Phosphoramidites
DNA/RNA Synthesis
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Others
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DMT-L-dA(bz) Phosphoramidite (L-DA-CE phosphoramidite; compound 20c) is typically used in the synthesis of DNA. DMT-L-dA(bz) Phosphoramidite can be used in studying DNA-drug interactions .
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- HY-164252
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5′-O-Trityl-2′-deoxy-2′-fluorouridine
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DNA/RNA Synthesis
Phosphoramidites
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Others
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DMT-2'-FU (5'-O-Trityl-2'-deoxy-2'-fluorouridine)Is with DMTProtecting Group (Protect 5'end), FLabeled uridine ribonucleotide.
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- HY-138613
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- HY-154413
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- HY-B1311R
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SKF-525A (Standard); U-5446 (Standard); RP-5171 (Standard)
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Reference Standards
Cytochrome P450
Monoamine Oxidase
Bcl-2 Family
Survivin
PARP
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Neurological Disease
Inflammation/Immunology
Cancer
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Proadifen (hydrochloride) (Standard) is the analytical standard of Proadifen (hydrochloride). This product is intended for research and analytical applications. Proadifen (SKF-525A) hydrochloride is a non-competitive Cytochrome P450 inhibitor with an IC50 value of 19 μM. Proadifen hydrochloride reduces monoamine oxidase A (MAO-A) activity and reverses the antidepressantlike behavioral effect of Imipramine (HY-B1490A) and Desipramine (HY-B1272A) in rats. Proadifen hydrochloride also reduces N, N-dimethyltryptamine (DMT) metabolism in liver microsomes and inhibits N-demethylationand Acridone (HY-W007771) formation. Proadifen hydrochloride augments Lipopolysaccharide (LPS) (HY-D1056)-induced fever and exacerbates Prostaglandin E2 (PGE2) (HY-101952) levels in the rat. Proadifen hydrochloride is promising for research of metabolism-related deseases, ovarian carcinoma, inflammation and dopamine neurons-related deseases [4] .
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- HY-177200
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- HY-W048482S4
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DMT-2'O-TBDMS-rU phosphoramidite-15N
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Isotope-Labeled Compounds
DNA/RNA Synthesis
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Others
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rU Phosphoramidite- 15N (DMT-2'O-TBDMS-rU phosphoramidite- 15N) is 15N labeled rU Phosphoramidite (HY-W048482). rU Phosphoramidite is a phosphorite monomer that can be used in the synthesis of oligonucleotides.
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- HY-W048482S3
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DMT-2'O-TBDMS-rU phosphoramidite-15N2
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Isotope-Labeled Compounds
DNA/RNA Synthesis
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Others
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rU Phosphoramidite- 15N2 (DMT-2'O-TBDMS-rU phosphoramidite- 15N2) is 15N labeled rU Phosphoramidite (HY-W048482). rU Phosphoramidite is a phosphorite monomer that can be used in the synthesis of oligonucleotides.
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- HY-W048482S2
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DMT-2'O-TBDMS-rU phosphoramidite-13C9
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Isotope-Labeled Compounds
DNA/RNA Synthesis
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Others
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rU Phosphoramidite- 13C9 (DMT-2'O-TBDMS-rU phosphoramidite- 13C9) is 13C-labeled rU Phosphoramidite (HY-W048482). rU Phosphoramidite is a phosphorite monomer that can be used in the synthesis of oligonucleotides.
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- HY-49000
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- HY-49210
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- HY-138605
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- HY-104014R
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Reference Standards
DNA/RNA Synthesis
Nucleoside Antimetabolite/Analog
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Others
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DMT-2'O-MOE-rG(ib) Phosphoramidite (Standard) is the analytical standard of DMT-2'O-MOE-rG(ib) Phosphoramidite (HY-104014). This product is intended for research and analytical applications. DMT-2'O-MOE-rG(ib) Phosphoramidite belongs to cyanoethyl-protected nucleoside phosphoramidites. DMT-2'O-MOE-rG(ib) Phosphoramidite is a derivative of nucleotide and guanosine. DMT-2'O-MOE-rG(ib) Phosphoramidite can be used for the stereochemical synthesis of phosphorothioate oligonucleotides .
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- HY-104017R
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Nucleoside Antimetabolite/Analog
Reference Standards
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Others
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DMT-2'-O-MOE-rA(Bz) phosphoramidite (Standard) is the analytical standard of DMT-2'-O-MOE-rA(Bz) phosphoramidite (HY-104017). This product is intended for research and analytical applications. DMT-2'-O-MOE-rA(Bz) phosphoramidite is an adenine nucleoside analog. DMT-2'-O-MOE-rA(Bz) phosphoramidite can be used in research on oligonucleotide synthesis .
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- HY-W425093
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- HY-W1121791
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- HY-43049
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Bz-rA Phosphoramidite enantiomer
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DNA/RNA Synthesis
Phosphoramidites
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Others
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DMT-2'O-TBDMS-rA(bz) Phosphoramidite enantiomer is a phosphoramidite that can be used in the synthesis of oligonucleotides.
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- HY-177478
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- HY-W1121775
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- HY-W1121763
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- HY-W1121774
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- HY-138586S
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- HY-W1119946
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Nucleoside Antimetabolite/Analog
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Others
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(3R,5S)-5-O-DMT-3-pyrrolidinol-benzyl laurate is a laurate derivative with a dimethoxytrityl (DMT) protecting group and a 3-pyrrolidinol structure. (3R,5S)-5-O-DMT-3-pyrrolidinol-benzyl laurate can be used for oligonucleotide modification or as a lipid-soluble delivery vehicle.
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- HY-W1130289
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- HY-182217
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- HY-D1884
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Phosphoramidites
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6-FAM-DMT-PA is a phosphoramidite that can be used in the synthesis of oligonucleotides.
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- HY-W1130272
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- HY-W1130268
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- HY-W1121767
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- HY-W460666
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Phosphoramidites
Drug Intermediate
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Cancer
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5'-O-DMT-N2-Ibu-2'-OMe-G is a crucial intermediate for the synthesis of antisense oligonucleotides. 5'-O-DMT-N2-Ibu-2'-OMe-G is involved in constructing antisense oligonucleotides with specific sequences, which can bind complementarily to the targeted mRNA. 5'-O-DMT-N2-Ibu-2'-OMe-G blocks the translation process of mRNA, thereby inhibiting the expression of specific proteins and playing a role in regulating gene expression. 5'-O-DMT-N2-Ibu-2'-OMe-G is promising for research of genetic diseases and tumors .
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- HY-D2737
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BHQ-2 DMT amidite
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Fluorescent Dye
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Others
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DMT-BH2 amidite (BHQ-2 DMT amidite) is a black quencher dye for the synthesis of dual-labeled oligonucleotide probes for qPCR bearing 5'-quencher. This quencher is ideal for HEX, JOE, ROX, Cyanine5, and other dyes with emissions in the orange and red parts of the spectrum.
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- HY-164249
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- HY-W881217
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DNA/RNA Synthesis
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Others
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DMT-iBu-G-(S)-GNA Phosphoramidite is a phosphoramidite monomer used in nucleic acid synthesis, such as oligonucleotides.
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- HY-154366
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N1-Methylpseudouridine CEP
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Nucleoside Antimetabolite/Analog
Phosphoramidites
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Cancer
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5'-DMT-2'-O-TBDMS-N1-Methyl-PseudoUridine-CE-Phosphoramidite is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
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- HY-W784557
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Phosphoramidites
Biochemical Assay Reagents
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Others
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O-DMT-2,2-di(ethoxycarbonyl)propan-1,3-diol is a chemical phosphorylation reagent used for the synthesis of 5'-phosphorylated oligonucleotides. It contains the chemical protective group DMT in its structure, which allows for purification through C18 columns or reversed-phase chromatography .
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- HY-W102322
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- HY-177293
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- HY-21545
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- HY-138610
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- HY-W008848
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- HY-132136
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- HY-177294
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- HY-D2742
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BHQ-1 DMT amidite
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Fluorescent Dye
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Others
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DMT-BH1 amidite (BHQ-1 DMT amidite) is a true dark quencher with broad absorption curve which covers the visible spectrum with maximum in green to yellow region. It is used for the synthesis of dual labeled oligonucleotide probes for qPCR bearing 5'-quencher DusQ 1 and other FRET applications for multiplexing assays.
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- HY-W048482S1
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DMT-2'O-TBDMS-rU phosphoramidite-13C9,15N2
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Isotope-Labeled Compounds
DNA/RNA Synthesis
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Others
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rU Phosphoramidite- 13C9, 15N2 (DMT-2'O-TBDMS-rU phosphoramidite- 13C9, 15N2) is 13C and 15N-labeled rU Phosphoramidite (HY-W048482). rU Phosphoramidite is a phosphorite monomer that can be used in the synthesis of oligonucleotides.
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- HY-W793155
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Nucleoside Antimetabolite/Analog
Phosphoramidites
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Others
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N6-Benzoyl-2'-deoxy-3'-O-DMT-adenosine is a nucleoside analog that is structurally related to the natural nucleotide adenosine. N6-Benzoyl-2'-deoxy-3'-O-DMT-adenosine is an activator of ribonucleotide reductase, which converts ribonucleosides to deoxyribonucleosides.
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- HY-138586
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- HY-138600
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- HY-177245
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- HY-170049
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- HY-W048482S
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DMT-2'O-TBDMS-rU phosphoramidite-13C2,d1
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Isotope-Labeled Compounds
DNA/RNA Synthesis
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Others
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rU Phosphoramidite- 13C2,d1 (DMT-2'O-TBDMS-rU phosphoramidite- 13C2,d1) is deuterium and 13C-labeled rU Phosphoramidite (HY-W048482). rU Phosphoramidite is a phosphorite monomer that can be used in the synthesis of oligonucleotides.
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- HY-177336
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- HY-W008848A
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- HY-138106
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Amino Acid Derivatives
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Others
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Fmoc-D-Cit-OH is citrulline with an Fmoc protecting group, which can be used to synthesize bioactive peptide mimetics, such as H-Dmt-D-Cit-Aba-b-Ala-NMe-30,50-(CF3)2-Bn and H-Dmt-D-Cit-Aba-b-Ala-NMe-Bn with neurokinin-1 antagonist activity .
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- HY-138604
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- HY-W048494
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N4-Benzoyl-5-methyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-methoxyethyl-cytidine
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Phosphoramidites
Nucleoside Antimetabolite/Analog
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Others
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N4-Bz-5-Me-DMT-2'-O-MOE-Cr (N4-Benzoyl-5-methyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-methoxyethyl-cytidine) is a nucleoside analog containing a dimethoxytrityl (DMT) group, commonly used in the synthesis of nucleic acids.
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- HY-W091754
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Nucleoside Antimetabolite/Analog
Phosphoramidites
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Others
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5'-O-Dmt-n2-isobutyryl-2'-o-methyl-d-guanosine is a nucleoside that is made using an oxime opening of the 5' position and a methylation at the 2' position. 5'-O-Dmt-n2-isobutyryl-2'-o-methyl-d-guanosine has been shown to have an affinity for tissues in a chemotactic assay.
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- HY-W077279
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N4-Acetyl-2'-deoxy-5'-O-DMT-cytidine
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Phosphoramidites
DNA/RNA Synthesis
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Others
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5'-O-DMT-N4-Ac-dC (N4-Acetyl-2'-deoxy-5'-O-DMT-cytidine, compound 7), a deoxynucleoside, can be used to synthesize of dodecyl phosphoramidite which is the raw material for dod‐DNA (amphiphilic DNA containing an internal hydrophobic region consisting of dodecyl phosphotriester linkages) synthesis .
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- HY-138614
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- HY-138611
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- HY-171704
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- HY-138603
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- HY-138612
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- HY-202974
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- HY-43059
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- HY-W000665
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Dmt
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Opioid Receptor
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Neurological Disease
|
|
2,6-Dimethyl-L-tyrosine (Dmt) is a tyrosine derivative that enhances receptor affinity, functional bioactivity and in vivo analgesia of opioid peptides .
|
-
- HY-21601
-
-
- HY-12619
-
|
|
HSP
|
Cancer
|
|
DMT003096 is a HSP70 inhibitor. HSP70 has been reported to be upregulated in various cancers including breast, lung, colon, and cervix .
|
-
- HY-W336559
-
-
- HY-W1119952
-
|
|
Biochemical Assay Reagents
|
Others
|
|
(3R,5S)-5-O-DMT-3-pyrrolidinol-12-oxododecanoic acid is a biochemical assay reagent that can be used to synthesize a variety of compounds. (3R,5S)-5-O-DMT-3-pyrrolidinol-12-oxododecanoic acid is the intermediate for the synthesis of complex compounds and building blocks.
|
-
- HY-171114
-
|
|
Liposome
|
Others
|
|
DMT7 is an ionizable cationic lipid (pKa = 6.5) that can be used to generate lipid nanoparticles (LNPs) for delivery of mRNA and anticancer drugs in the body .
|
-
- HY-177333
-
-
- HY-173175
-
-
- HY-W1119944
-
-
- HY-138602
-
-
- HY-138598
-
-
- HY-20140
-
-
- HY-48873
-
-
- HY-46369
-
-
- HY-W782181
-
-
- HY-W087199
-
-
- HY-154955
-
-
- HY-171938
-
-
- HY-W114328
-
-
- HY-182990
-
|
|
DNA/RNA Synthesis
|
Others
|
|
N3-Methylcytidine phosphoramidite [5′-O-DMT2′-O-TBDMS-m3 CAc] is a phosphoramidite monomer. Phosphoramidites can be used in the synthesis of oligonucleotides .
|
-
- HY-152970
-
|
|
Nucleoside Antimetabolite/Analog
Phosphoramidites
|
Others
|
|
7'-O-DMT-morpholino uracil is a uridine analog. Uridine has potential antiepileptic effects, and its analogs can be used to study anticonvulsant and anxiolytic activities, as well as to develop new antihypertensive agents .
|
-
- HY-101528R
-
|
|
iGluR
Reference Standards
|
Neurological Disease
|
|
IDRA 21 (Standard) is the analytical standard of IDRA 21 (HY-101528). This product is intended for research and analytical applications. IDRA 21 is a positive and orally active modulator of the AMPA receptor. IDRA 21 facilitates excitatory neurotransmission via GluR1/2 receptors. IDRA 21 has the potential for the research of cognitive/memory disorders, including those associated with aging .
|
-
- HY-101528
-
|
|
iGluR
|
Neurological Disease
|
|
IDRA 21 is a positive and orally active modulator of the AMPA receptor. IDRA 21 facilitates excitatory neurotransmission via GluR1/2 receptors. IDRA 21 has the potential for the research of cognitive/memory disorders, including those associated with aging .
|
-
- HY-W008662
-
|
|
Phosphoramidites
Filovirus
|
Infection
|
|
2'-Deoxy-5'-O-DMT-2'-fluorouridine, a nucleoside analogue, is a 5’-O-DMTr-5-FUDR derivative with potent anti-yellow fever (YFV) activity .
|
-
- HY-W1121766
-
|
|
DNA/RNA Synthesis
Phosphoramidites
|
Others
|
|
5'-O-DMT-2'-O-[2-(Methylamino)-2-oxoethyl]-5-Me-uridine 3'-CE phosphoramidite is a phosphoramidite that can be used in the synthesis of oligonucleotides.
|
-
- HY-W726201
-
|
|
Nucleoside Antimetabolite/Analog
Phosphoramidites
|
Cancer
|
|
2'-Deoxy-5'-O-DMT-5-fluorouridine 3'-CE phosphoramidite is a nucleoside phosphoramidite analogue employed in oligonucleotide synthesis. This compound contributes to crafting therapeutic oligonucleotides for drugs targeting cancers.
|
-
- HY-W1119957
-
|
|
Biochemical Assay Reagents
|
Others
|
|
5'-VP-2'-OMe-U phosphoramidite is a phosphoramidite that contains 5’ DMT and uridine with 2’-O-methyl protection. 5'-VP-2'-OMe-U Phosphoramidite can be used to synthesize oligonucleotide.
|
-
- HY-112144
-
|
|
HIF/HIF Prolyl-Hydroxylase
|
Metabolic Disease
Inflammation/Immunology
|
|
TP0463518 is an orally active, competitive pan-inhibitor of hypoxia-inducible factor prolyl hydroxylases PHD1/2/3. TP0463518 competitively inhibits human PHD1 (IC50=18 nM), PHD2 (Ki=5.3 nM), and PHD3 (IC50=63 nM), and targets monkey PHD2 with an IC50 of 22 nM. TP0463518 inhibits PHD-catalyzed hydroxylation to stabilize HIFα, thereby upregulating erythropoietin (EPO) expression and enhancing intestinal iron absorption (such as increased DMT-1 and dCYTb expression), improving anemia. TP0463518 is mainly used for the research of renal anemia and inflammatory anemia .
|
-
- HY-104039
-
|
|
Nucleoside Antimetabolite/Analog
Phosphoramidites
|
Cancer
|
|
2'-Deoxy-5'-O-DMT-5-methylcytidine is a cytidine analog. Cytidine analogs have a mechanism of inhibiting DNA methyltransferases (such as Zebularine, HY-13420), and have potential anti-metabolic and anti-tumor activities .
|
-
- HY-W1119943
-
|
|
Nucleoside Antimetabolite/Analog
|
Others
|
|
2'-OMe-8-Me-DMF-G Phosphoramidite is a phosphoramidite compound containing modified guanine (G) and a dimethoxytrityl (DMT) group. 2'-OMe-8-Me-DMF-G Phosphoramidite can be used in RNA oligonucleotide synthesis.
|
-
- HY-154019
-
|
|
Nucleoside Antimetabolite/Analog
Phosphoramidites
|
Cancer
|
|
N4-Benzoyl-5'-O-DMT-5-methylcytidine is a cytidine analog. Cytidine analogs have a mechanism of inhibiting DNA methyltransferases (such as Zebularine, HY-13420), and have potential anti-metabolic and anti-tumor activities .
|
-
- HY-154410
-
|
|
Nucleoside Antimetabolite/Analog
Phosphoramidites
|
Cancer
|
|
5’-O-DMT-2’-deoxy-2’-fluoro-β-D-arabinouridine is a uridine analog. Uridine has potential antiepileptic effects, and its analogs can be used to study anticonvulsant and anxiolytic activities, as well as to develop new antihypertensive agents .
|
-
- HY-169466
-
|
|
Drug Derivative
|
Neurological Disease
|
|
5-Methoxy-N,N-dimethyltryptamine Nb-oxide is an indole alkaloid. 5-Methoxy-N,N-dimethyltryptamine Nb-oxide is the N-oxide form of 5-Methoxy-N,N-dimethyltryptamine (5-MeO-DMT), which is a known psychoactive substance .
|
-
- HY-152978
-
|
|
Nucleoside Antimetabolite/Analog
Phosphoramidites
|
Others
|
|
2'-Deoxy-5'-O-DMT-N4-Fmoc-5-methylcytidine is a cytidine analog. Cytidine analogs have a mechanism of inhibiting DNA methyltransferases (such as Zebularine, HY-13420), and have potential anti-metabolic and anti-tumor activities .
|
-
- HY-154309
-
|
|
Nucleoside Antimetabolite/Analog
Phosphoramidites
|
Cancer
|
|
3'-O-tert-Butyldimethylsilyl-5'-O-DMT-2'-deoxyadenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
-
- HY-154604
-
|
|
Nucleoside Antimetabolite/Analog
Phosphoramidites
|
Cancer
|
|
1-(2'-Deoxy-5'-O-DMT-2'-fluoro-b-D-arabinofuranosyl)thymine 3'-CE phosphoramidite is a thymidine analog. Analogs of this series have insertional activity towards replicated DNA. They can be used to label cells and track DNA synthesis .
|
-
- HY-154363
-
|
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
3-Cyanovinyl-9-(5’-O-DMT-2’-deoxyribofuranosyl)carbazole is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
-
- HY-154267
-
|
|
Nucleoside Antimetabolite/Analog
Phosphoramidites
|
Cancer
|
|
5'-O-DMT-2-thio-2'-dU-3'-phosphoramidite is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
-
- HY-154450
-
|
|
Nucleoside Antimetabolite/Analog
Phosphoramidites
|
Cancer
|
|
N4-Benzoyl-5’-O-DMT-3’-O-(2-methoxyethyl)-5-methylcytidine is a cytidine analog. Cytidine analogs have a mechanism of inhibiting DNA methyltransferases (such as Zebularine, HY-13420), and have potential anti-metabolic and anti-tumor activities .
|
-
- HY-154229
-
|
|
Nucleoside Antimetabolite/Analog
Phosphoramidites
|
Cancer
|
|
3’-O-DMT-N2-isobutyryl-2’-O-(2-methoxyethyl)guanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
-
- HY-154030
-
|
|
Nucleoside Antimetabolite/Analog
Phosphoramidites
|
Cancer
|
|
N6-Benzoyl-3'-deoxy-5'-O-DMT-3'-fluoroadenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
-
- HY-152979
-
|
|
DNA/RNA Synthesis
Phosphoramidites
|
Others
|
|
2'-Deoxy-5'-O-DMT-N4-Fmoc-5-methylcytidine 3'-CE-phosphoramidite is a cytidine analog. Cytidine analogs have a mechanism of inhibiting DNA methyltransferases (such as Zebularine, HY-13420), and have potential anti-metabolic and anti-tumor activities .
|
-
- HY-154441
-
|
|
Nucleoside Antimetabolite/Analog
Phosphoramidites
|
Cancer
|
|
N4-Benzoyl-3'-O-DMT-2'-O-(2-methoxyethyl)-5-methylcytidine is a cytidine analog. Cytidine analogs have a mechanism of inhibiting DNA methyltransferases (such as Zebularine, HY-13420), and have potential anti-metabolic and anti-tumor activities .
|
-
- HY-154221
-
|
|
Nucleoside Antimetabolite/Analog
Phosphoramidites
|
Cancer
|
|
N4-Benzoyl-2'-deoxy-5'-O-DMT-2',2'-difluorocytidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
-
- HY-154260
-
|
|
Nucleoside Antimetabolite/Analog
Phosphoramidites
|
Cancer
|
|
N6-Benzoyl-3'-O-DMT-2'-O-(2-methoxyethyl) adenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
-
- HY-154207
-
|
|
Nucleoside Antimetabolite/Analog
Phosphoramidites
|
Cancer
|
|
2’-O-Acetyl-N4-benzoyl-5’-O-DMT arabinocytidine 3’-O-phosphoramidite is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
-
- HY-124703
-
|
|
Ferroportin
|
Others
|
|
Pyrimidinone 8 is a reversible linear non-competitive inhibitor of divalent metal transporter 1 (DMT1), with a Ki of 20 μM (hDMT1). Pyrimidinone 8 does not affect hDMT1 cell surface expression and shows no dependence with the extracellular pH. Pyrimidinone 8 can inhibit hDMT1-mediated iron uptake, with an IC50 of 13.8 μM .
|
-
- HY-152988
-
|
|
Nucleoside Antimetabolite/Analog
Phosphoramidites
|
Others
|
|
N2-iso-Butyroyl-7'-O-DMT-morpholinoguanine is a guanosine analog. Some guanosine analogs have immunostimulatory activity. In some animal models, they also induce type I interferons, producing antiviral effects. Studies have shown that the functional activity of guanosine analogs is dependent on the activation of Toll-like receptor 7 (TLR7) .
|
-
- HY-152973
-
|
|
Nucleoside Antimetabolite/Analog
Phosphoramidites
|
Others
|
|
7'-O-DMT-morpholino thymine is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277) .
|
-
- HY-177973
-
-
- HY-154350
-
|
|
Nucleoside Antimetabolite/Analog
Phosphoramidites
|
Cancer
|
|
5'-O-DMT-N2-isobutyryl-2'-O-propargylguanosine is a guanosine analog. Some guanosine analogs have immunostimulatory activity. In some animal models, they also induce type I interferons, producing antiviral effects. Studies have shown that the functional activity of guanosine analogs is dependent on the activation of Toll-like receptor 7 (TLR7) .
|
-
- HY-138589
-
|
|
DNA/RNA Synthesis
Nucleoside Antimetabolite/Analog
|
Infection
Cancer
|
|
5'-O-TBDMS-dG is a modified nucleoside. 5'-O-DMT-2'-O-TBDMS-rI can be used in the synthesis of deoxyribonucleic acid or nucleic acid. 7-TFA-ap-7-Deaza-dG is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-154548
-
|
|
Nucleoside Antimetabolite/Analog
Phosphoramidites
|
Others
|
|
N2-iso-Butyroyl-5’-O-DMT-3’-O-(methoxyethyl)guanosine is a guanosine analog. Some guanosine analogs have immunostimulatory activity. In some animal models, they also induce type I interferons, producing antiviral effects. Studies have shown that the functional activity of guanosine analogs is dependent on the activation of Toll-like receptor 7 (TLR7) .
|
-
- HY-152984
-
|
|
Nucleoside Antimetabolite/Analog
Phosphoramidites
|
Others
|
|
N6-Benzoyl-7'-O-DMT-morpholino adenine is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277) .
|
-
- HY-W097792
-
|
5'-O-DMT-dU
|
DNA/RNA Synthesis
|
Others
|
|
5'-O-(4,4'-Dimethoxytrityl)-2'-deoxyuridine (5'-O-DMT-dU) is a competitive inhibitor of E. coli dUTP nucleotidohydrolase (dUTPase), with the Ki higher than 1000 μM. 5'-O-(4,4'-Dimethoxytrityl)-2'-deoxyuridine can be used in machine-assisted DNA synthesis by synthesizing nucleosidic phosphoramidite blocks .
|
-
- HY-W010702
-
|
N2-Isobutyryl-5′-O-(4,4′-dimethoxytrityl)-2′-deoxyguanosine
|
Nucleoside Antimetabolite/Analog
Phosphoramidites
|
Others
|
|
5'-O-DMT-N2-ibu-dG (N2-Isobutyryl-5′-O-(4,4′-dimethoxytrityl)-2′-deoxyguanosine) is a protected 2'-deoxyguanosine derivative with 5'-O-(4,4'-dimethoxytriphenylmethyl) and N2-isobutyryl protecting groups, and serves as a building block in oligonucleotide synthesis .
|
-
- HY-154464
-
|
|
Nucleoside Antimetabolite/Analog
Phosphoramidites
|
Cancer
|
|
N2-iso-Butyroyl-5'-O-DMT-3'-deoxy-3'-fluoroguanosine is a guanosine analog. Some guanosine analogs have immunostimulatory activity. In some animal models, they also induce type I interferons, producing antiviral effects. Studies have shown that the functional activity of guanosine analogs is dependent on the activation of Toll-like receptor 7 (TLR7) .
|
-
- HY-45281
-
|
|
Nucleoside Antimetabolite/Analog
Phosphoramidites
|
Others
|
|
N6-Benzoyl-5'-O-DMT-3'-O-methyladenosine 3'CE-phosphoramidite is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277) .
|
-
- HY-152983
-
|
|
DNA/RNA Synthesis
Phosphoramidites
|
Others
|
|
2'-Deoxy-5'-O-DMT-N6-Fmoc-adenosine 3'CE-phosphoramidite is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277) .
|
-
- HY-154419
-
|
|
Nucleoside Antimetabolite/Analog
Phosphoramidites
|
Cancer
|
|
N6-Benzoyl-2'-O-tert-butyldimethylsilyl-3'-O-DMT-adenosine is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277) .
|
-
- HY-154339
-
|
|
Nucleoside Antimetabolite/Analog
Phosphoramidites
|
Cancer
|
|
N4-Benzoyl-5'-O-DMT-2'-O-propargyl adenosine is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277) .
|
-
- HY-W141392
-
|
|
Nucleoside Antimetabolite/Analog
Xanthine Oxidase
Phosphoramidites
|
Cancer
|
|
2'-Fluoro-5'-O-DMT-2'-deoxyinosine-3'-CE-phosphoramidite is a hypoxanthine analog. Hypoxanthine is a kind of purine base mainly present in muscle tissue. And it is a metabolite produced by purine oxidase acting on xanthine. Hypoxanthine has typical anti-inflammatory effects and is a potential endogenous poly(ADP-ribose) polymerase (PARP) inhibitor. It is cytoprotective by inhibiting PAPR activity, inhibiting peroxynitrite-induced mitochondrial depolarization and secondary superoxide production. Hypoxanthine can also be used as an indicator of hypoxia .
|
-
- HY-W392836
-
|
|
Nucleoside Antimetabolite/Analog
Xanthine Oxidase
Phosphoramidites
|
Cancer
|
|
2'-O-Methyl-5'-O-dmt-inosine-3'-CE-phosphoramidite is a hypoxanthine analog. Hypoxanthine is a kind of purine base mainly present in muscle tissue. And it is a metabolite produced by purine oxidase acting on xanthine. Hypoxanthine has typical anti-inflammatory effects and is a potential endogenous poly(ADP-ribose) polymerase (PARP) inhibitor. It is cytoprotective by inhibiting PAPR activity, inhibiting peroxynitrite-induced mitochondrial depolarization and secondary superoxide production. Hypoxanthine can also be used as an indicator of hypoxia .
|
-
- HY-W010706
-
|
5'-O-DMT-N4-Bz-dC
|
Nucleoside Antimetabolite/Analog
|
Others
|
|
N4-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxycytidine (5'-O-DMT-N4-Bz-dC) can be used for synthesis oligodeoxynucleotides containing a 3'-S-phosphorothiolate (3'-PS) linkage. N4-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxycytidine is an useful tool for probing enzyme-catalyzed cleavage processes in DNA .
|
-
| Cat. No. |
Product Name |
Type |
-
- HY-D2737
-
|
BHQ-2 DMT amidite
|
Fluorescent Dye
|
|
DMT-BH2 amidite (BHQ-2 DMT amidite) is a black quencher dye for the synthesis of dual-labeled oligonucleotide probes for qPCR bearing 5'-quencher. This quencher is ideal for HEX, JOE, ROX, Cyanine5, and other dyes with emissions in the orange and red parts of the spectrum.
|
-
- HY-D1884
-
|
|
Fluorescent Dye
|
|
6-FAM-DMT-PA is a phosphoramidite that can be used in the synthesis of oligonucleotides.
|
| Cat. No. |
Product Name |
Type |
-
- HY-21997
-
|
|
Biochemical Assay Reagents
|
|
DMT-2'fluoro-da(bz) amidite is a key intermediate for synthesizing antisense oligonucleotides with high nuclease resistance, high RNA binding affinity, and maintained base-pair specificity .
|
-
- HY-W013068
-
-
- HY-W013059
-
-
- HY-W008849
-
|
|
Biochemical Assay Reagents
|
|
DMT-dC (bz) Phosphoramidite is a protected deoxycytidine phosphoramidite monomer, as well as a building block for mechanochemical DNA synthesis. DMT-dC (bz) Phosphoramidite serves as a reagent for oligonucleotide synthesis .
|
-
- HY-W008848
-
|
|
Biochemical Assay Reagents
|
|
DMT-dG(ib) Phosphoramidite is a phosphoramidite monomer that can be used in the synthesis of DNA and related molecules .
|
-
- HY-W093086
-
-
- HY-132136
-
|
|
Biochemical Assay Reagents
|
|
DMT-dU-CE Phosphoramidite is a nucleoside molecule that can be used in DNA synthesis and DNA sequencing .
|
-
- HY-W077279
-
|
N4-Acetyl-2'-deoxy-5'-O-DMT-cytidine
|
Biochemical Assay Reagents
|
|
5'-O-DMT-N4-Ac-dC (N4-Acetyl-2'-deoxy-5'-O-DMT-cytidine, compound 7), a deoxynucleoside, can be used to synthesize of dodecyl phosphoramidite which is the raw material for dod‐DNA (amphiphilic DNA containing an internal hydrophobic region consisting of dodecyl phosphotriester linkages) synthesis .
|
-
- HY-W097792
-
|
5'-O-DMT-dU
|
Biochemical Assay Reagents
|
|
5'-O-(4,4'-Dimethoxytrityl)-2'-deoxyuridine (5'-O-DMT-dU) is a competitive inhibitor of E. coli dUTP nucleotidohydrolase (dUTPase), with the Ki higher than 1000 μM. 5'-O-(4,4'-Dimethoxytrityl)-2'-deoxyuridine can be used in machine-assisted DNA synthesis by synthesizing nucleosidic phosphoramidite blocks .
|
-
- HY-W013059R
-
|
DA-CE phosphoramidite (Standard)
|
Biochemical Assay Reagents
|
|
DMT-dA(bz) Phosphoramidite (Standard) is the analytical standard of DMT-dA(bz) Phosphoramidite. This product is intended for research and analytical applications. DMT-dA(bz) Phosphoramidite is a phosphoramide monomer for the synthesis of oligonucleotides (ONs) through formation of DNA dimers and trimers via mechanochemistry .
|
| Cat. No. |
Product Name |
Target |
Research Area |
-
- HY-W000665
-
|
Dmt
|
Opioid Receptor
|
Neurological Disease
|
|
2,6-Dimethyl-L-tyrosine (Dmt) is a tyrosine derivative that enhances receptor affinity, functional bioactivity and in vivo analgesia of opioid peptides .
|
-
- HY-P5131
-
|
|
Opioid Receptor
|
Others
|
|
[Dmt1]DALDA is a potent and long-acting analgesic binds to the mu opioid receptor with high affinity and selectivity. [Dmt1]DALDA is a full agonist at hMOR (Kd = 0.199 nM) and hDOR, but only partial agonist against hKOR .
|
-
- HY-138106
-
|
|
Amino Acid Derivatives
|
Others
|
|
Fmoc-D-Cit-OH is citrulline with an Fmoc protecting group, which can be used to synthesize bioactive peptide mimetics, such as H-Dmt-D-Cit-Aba-b-Ala-NMe-30,50-(CF3)2-Bn and H-Dmt-D-Cit-Aba-b-Ala-NMe-Bn with neurokinin-1 antagonist activity .
|
| Cat. No. |
Product Name |
Category |
Target |
Chemical Structure |
| Cat. No. |
Product Name |
Chemical Structure |
-
- HY-W013059S
-
|
|
|
DMT-dA(bz) Phosphoramidite- 13C10, 15N5 is the 13C and 15N labeled DMT-dA(bz) Phosphoramidite . DMT-dA(bz) Phosphoramidite is typically used in the synthesis of DNA .
|
-
-
- HY-W008848S
-
|
|
|
DMT-dG(ib) Phosphoramidite- 13C10, 15N5 is the 13C and 15N labeled DMT-dG(ib) Phosphoramidite (HY-W008848). DMT-dG(ib) Phosphoramidite is a phosphoramidite monomer that can be used in the synthesis of DNA and related molecules .
|
-
-
- HY-W013059S2
-
|
|
|
DMT-dA(bz) Phosphoramidite-d9 (DA-CE phosphoramidite-d9) is deuterium labeled DMT-dA(bz) Phosphoramidite (HY-W013059). DMT-dA(bz) Phosphoramidite is typically used in the synthesis of DNA.
|
-
-
- HY-150658S
-
|
|
|
DMT-2′O-TBDMS-rA(ac)-1- 15N phosphoramidite is the 15N labeled DMT-2′O-TBDMS-rA(ac) phosphoramidite .
|
-
-
- HY-W013068S1
-
|
|
|
DMT-dT Phosphoramidite- 15N2 is the 15N labeled DMT-dT Phosphoramidite . DMT-dT Phosphoramidite is typically used in the synthesis of DNA .
|
-
-
- HY-W013068S3
-
|
|
|
DMT-dT Phosphoramidite-d11 is deuterium labeled DMT-dT Phosphoramidite (HY-W013068). DMT-dT Phosphoramidite is typically used in the synthesis of DNA.
|
-
-
- HY-W013068S2
-
|
|
|
DMT-dT Phosphoramidite- 13C is 13C-labeled DMT-dT Phosphoramidite (HY-W013068). DMT-dT Phosphoramidite is typically used in the synthesis of DNA.
|
-
-
- HY-W013059S1
-
|
|
|
DMT-dA(bz) Phosphoramidite- 15N5 is the 15N labeled DMT-dA(bz) Phosphoramidite . DMT-dA(bz) Phosphoramidite is typically used in the synthesis of DNA .
|
-
-
- HY-W013068S
-
|
|
|
DMT-dT Phosphoramidite- 13C10, 15N2 is the 13C and 15N labeled DMT-dT Phosphoramidite . DMT-dT Phosphoramidite is typically used in the synthesis of DNA .
|
-
-
- HY-W008848S1
-
|
|
|
DMT-dG(ib) Phosphoramidite- 15N5 is the 15N labeled DMT-dG(ib) Phosphoramidite (HY-W008848). DMT-dG(ib) Phosphoramidite is a phosphoramidite monomer that can be used in the synthesis of DNA and related molecules .
|
-
-
- HY-W048482S4
-
|
|
|
rU Phosphoramidite- 15N (DMT-2'O-TBDMS-rU phosphoramidite- 15N) is 15N labeled rU Phosphoramidite (HY-W048482). rU Phosphoramidite is a phosphorite monomer that can be used in the synthesis of oligonucleotides.
|
-
-
- HY-W048482S3
-
|
|
|
rU Phosphoramidite- 15N2 (DMT-2'O-TBDMS-rU phosphoramidite- 15N2) is 15N labeled rU Phosphoramidite (HY-W048482). rU Phosphoramidite is a phosphorite monomer that can be used in the synthesis of oligonucleotides.
|
-
-
- HY-W048482S2
-
|
|
|
rU Phosphoramidite- 13C9 (DMT-2'O-TBDMS-rU phosphoramidite- 13C9) is 13C-labeled rU Phosphoramidite (HY-W048482). rU Phosphoramidite is a phosphorite monomer that can be used in the synthesis of oligonucleotides.
|
-
-
- HY-W048482S1
-
|
|
|
rU Phosphoramidite- 13C9, 15N2 (DMT-2'O-TBDMS-rU phosphoramidite- 13C9, 15N2) is 13C and 15N-labeled rU Phosphoramidite (HY-W048482). rU Phosphoramidite is a phosphorite monomer that can be used in the synthesis of oligonucleotides.
|
-
-
- HY-W048482S
-
|
|
|
rU Phosphoramidite- 13C2,d1 (DMT-2'O-TBDMS-rU phosphoramidite- 13C2,d1) is deuterium and 13C-labeled rU Phosphoramidite (HY-W048482). rU Phosphoramidite is a phosphorite monomer that can be used in the synthesis of oligonucleotides.
|
-
-
- HY-138586S
-
|
|
|
DMT-dC(ac) Phosphoramidite- 13C9, 15N3 is the 13C- and 15N-labeled DMT-dC(ac) Phosphoramidite (HY-138586). DMT-dC(ac) Phosphoramidite (compound 30f) is a phosphoramidite derivative that can be used for the oligonucleotide synthesis .
|
-
| Cat. No. |
Product Name |
|
Classification |
-
- HY-138579
-
|
DMT-2'-O-Methyl-rG(ib) Phosphoramidite
|
|
Phosphoramidites
Guanine
|
|
2'-OMe-G(ibu) Phosphoramidite (DMT-2'-O-Methyl-rG(ib) Phosphoramidite) is a modified phosphoramidite monomer that can be used for the oligonucleotide synthesis .
|
-
- HY-45491
-
|
2'-F-Ac-dC Phosphoramidite; DMT-2′Fluoro-dC(ac) Phosphoramidite
|
|
Phosphoramidites
Cytosine
|
|
Dmt-2'-f-dc(ac) amidite (2'-F-Ac-dC Phosphoramidite) is a phosphoramidite which can be used in the preparation of cyclic purine dinucleotides .
|
-
- HY-21997
-
|
|
|
Phosphoramidites
Adenine
|
|
DMT-2'fluoro-da(bz) amidite is a key intermediate for synthesizing antisense oligonucleotides with high nuclease resistance, high RNA binding affinity, and maintained base-pair specificity .
|
-
- HY-W013068
-
-
- HY-104014
-
|
|
|
Phosphoramidites
Guanine
|
|
DMT-2'O-MOE-rG(ib) Phosphoramidite belongs to cyanoethyl-protected nucleoside phosphoramidites. DMT-2'O-MOE-rG(ib) Phosphoramidite is a derivative of nucleotide and guanosine. DMT-2'O-MOE-rG(ib) Phosphoramidite can be used for the stereochemical synthesis of phosphorothioate oligonucleotides .
|
-
- HY-45409
-
|
2'-F-dU Phosphoramidite
|
|
Phosphoramidites
Uracil
|
|
DMT-2’ Fluoro-dU Phosphoramidite (2'-F-dU Phosphoramidite) is a uridine phosphoramidite with a fluorine in the 2’ position. DMT-2’ Fluoro-dU Phosphoramidite could be used for nucleoside modification and synthesis of DNA .
|
-
- HY-W006102
-
|
DMT-2'O-TBDMS-rA(bz) Phosphoramidite
|
|
Phosphoramidites
Adenine
|
|
Bz-rA Phosphoramidite (DMT-2'O-TBDMS-rA(bz) Phosphoramidite) a phosphoramidite containing 5' DMT and the nucleoside adenosine (A) with Benzoyl (Bz) base protection, for use in oligonucleotide synthesis .
|
-
- HY-45492
-
|
2'-F-ibu-dG Phosphoramidite
|
|
Phosphoramidites
Guanine
|
|
DMT-2'Fluoro-DG(IB) Amidite (2'-F-ibu-dG Phosphoramidite) is a nucleoside that can be employed for oligonucleotide synthesis. DMT-2'Fluoro-DG(IB) Amidite can be used to prepare 4'-modified 2'-deoxy-2'-fluorouridine .
|
-
- HY-W101391
-
|
2'-O-Me-U Phosphoramidite
|
|
Phosphoramidites
Uracil
|
|
DMT-2'O-Methyl-rU Phosphoramidite (2'-O-Me-U Phosphoramidite) is a 2'-O-Me derivative, and can be used for oligonucleotide synthesis .
|
-
- HY-138585
-
|
|
|
Phosphoramidites
Guanine
|
|
DMT-dG(dmf) Phosphoramidite is a phosphinamide monomer that can be used in the preparation of oligonucleotides
|
-
- HY-104017
-
|
|
|
Phosphoramidites
Adenine
|
|
DMT-2'-O-MOE-rA(Bz) phosphoramidite is an adenine nucleoside analog. DMT-2'-O-MOE-rA(Bz) phosphoramidite can be used in research on oligonucleotide synthesis .
|
-
- HY-W013059
-
|
DA-CE phosphoramidite
|
|
Phosphoramidites
Adenine
|
|
DMT-dA(bz) Phosphoramidite is typically used in the synthesis of DNA .
|
-
- HY-46317
-
|
|
|
Phosphoramidites
Cytosine
|
|
DMT-5Me-dC(Bz)-CE Phosphoramidite is a chemical structural unit that can be used in solid-phase DNA synthesis. DMT-5Me-dC(Bz)-CE Phosphoramidite can introduce the 5-methylcytidine base into the DNA chain to enhance its stability and binding affinity. DMT-5Me-dC(Bz)-CE Phosphoramidite can be used to construct modified oligonucleotides, especially for constructing locked nucleic acids (LNA) .
|
-
- HY-W008849
-
|
|
|
Phosphoramidites
Cytosine
|
|
DMT-dC (bz) Phosphoramidite is a protected deoxycytidine phosphoramidite monomer, as well as a building block for mechanochemical DNA synthesis. DMT-dC (bz) Phosphoramidite serves as a reagent for oligonucleotide synthesis .
|
-
- HY-139988
-
-
- HY-W008848
-
|
|
|
Phosphoramidites
Guanine
|
|
DMT-dG(ib) Phosphoramidite is a phosphoramidite monomer that can be used in the synthesis of DNA and related molecules .
|
-
- HY-138586
-
|
|
|
Phosphoramidites
Cytosine
|
|
DMT-dC(ac) Phosphoramidite (compound 30f) is a phosphoramidite derivative that can be used for the oligonucleotide synthesis .
|
-
- HY-W010744
-
|
5'-O-DMT-dI; 2'-Deoxy-5'-O-DMT-inosine
|
|
Phosphoramidites
Hypoxanthine
|
|
DMT-dI (5'-O-DMT-dI) is a deoxyribonucleoside containing a hypoxanthine base. DMT-dI can be used to prepare convertible nucleoside derivatives to prepare modified oligonucleotides complementary to target genes for gene editing. DMT-dI can be used to study various conditions, disorders or diseases modified by adenosine .
|
-
- HY-W784557
-
|
|
|
Phosphoramidites
Other Phosphoramidite
|
|
O-DMT-2,2-di(ethoxycarbonyl)propan-1,3-diol is a chemical phosphorylation reagent used for the synthesis of 5'-phosphorylated oligonucleotides. It contains the chemical protective group DMT in its structure, which allows for purification through C18 columns or reversed-phase chromatography .
|
-
- HY-W093086
-
|
|
|
Phosphoramidites
Adenine
|
|
DMT-2'-F-Bz-dA is a phosphoramidite monomer that can be used for oligonucleotide synthesis.
|
-
- HY-W115186
-
|
|
|
Phosphoramidites
Cytosine
|
|
DMT-2'-OMe-Bz-C is a cytidine analog. Cytidine analogs have a mechanism of inhibiting DNA methyltransferases (such as Zebularine, HY-13420), and have potential anti-metabolic and anti-tumor activities .
|
-
- HY-138601
-
|
|
|
Phosphoramidites
Cytosine
|
|
5'-O-DMT-N4-Bz-5-Me-dC is a modified nucleoside. 5'-O-DMT-2'-O-TBDMS-rI can be used in the synthesis of deoxyribonucleic acid or nucleic acid.
|
-
- HY-138581
-
|
|
|
Phosphoramidites
Adenine
|
|
DMT-dA(PAc) Phosphoramidite is a dIPhosphoramidite and can be used for DNA or RNA synthesis.
|
-
- HY-21545
-
-
- HY-138610
-
-
- HY-132136
-
|
|
|
Phosphoramidites
Uracil
|
|
DMT-dU-CE Phosphoramidite is a nucleoside molecule that can be used in DNA synthesis and DNA sequencing .
|
-
- HY-138602
-
|
|
|
Phosphoramidites
Cytosine
|
|
5'-O-DMT-N4-Ac-2'-F-dC is a modified nucleotide commonly used in the synthesis of modified oligonucleotides.
|
-
- HY-49200
-
|
|
|
Phosphoramidites
Cytosine
|
|
DMT-2'-F-dC(Bz)-CE-Phosphoramidite is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
-
- HY-138606
-
-
- HY-W077279
-
|
N4-Acetyl-2'-deoxy-5'-O-DMT-cytidine
|
|
Phosphoramidites
Cytosine
|
|
5'-O-DMT-N4-Ac-dC (N4-Acetyl-2'-deoxy-5'-O-DMT-cytidine, compound 7), a deoxynucleoside, can be used to synthesize of dodecyl phosphoramidite which is the raw material for dod‐DNA (amphiphilic DNA containing an internal hydrophobic region consisting of dodecyl phosphotriester linkages) synthesis .
|
-
- HY-138603
-
-
- HY-43059
-
|
5'-O-DMT-2'-O-TBDMS-ibu-rG
|
|
Phosphoramidites
Guanine
|
|
5'-O-DMT-2'-O-iBu-N-Bz-Guanosine could be used for silyl protection of ribonucleosides .
|
-
- HY-W336559
-
|
|
|
Phosphoramidites
Cytosine
|
|
5-Me-DMT-2'-O-Me-C(Bz)-CE-Phosphoramidite is a phosphorite monomer that can be used in the synthesis of oligonucleotides.
|
-
- HY-43060
-
|
|
|
Phosphoramidites
Guanine
|
|
5'-DMT-3'-TBDMS-ibu-rG is is a modified nucleoside. 5'-DMT-3'-TBDMS-ibu-rG can be used in deoxyribonucleic acid synthesis.
|
-
- HY-160884
-
|
|
|
Phosphoramidites
Other Phosphoramidite
|
|
DMT-2'-OMe-D-Ribitol phosphoramidite (compound 9) is an abasic phosphoramidite monomer that can be used to introduce the abasic group Y34 into oligonucleotides .
|
-
- HY-43058
-
|
5'-O-DMT-N2-isobutyrylguanosine
|
|
Phosphoramidites
Guanine
|
|
5'-O-DMT-ibu-rG (5'-O-DMT-N2-isobutyrylguanosine) is a chemically modified guanosine derivative that can be used as a novel DNA-binding molecule for the development of effective and selective anti-cancer agents.
|
-
- HY-138608
-
-
- HY-164181
-
-
- HY-W102322
-
|
|
|
Phosphoramidites
Uracil
|
|
5'-O-DMT-2'-TBDMS-Uridine is a deoxyribonucleoside used for the oligonucleotide synthesis.
|
-
- HY-21601
-
|
|
|
Phosphoramidites
Adenine
|
|
5'-O-DMT-2'-O-TBDMS-N-Bz-Adenosine is an adenosine derivative and can be used as an intermediate for oligonucleotides synthesis.
|
-
- HY-W115309
-
|
5'-DMT-2'-F-ibu-dG
|
|
Phosphoramidites
Guanine
|
|
DMT-2'-F-iBu-G (5'-DMT-2'-F-ibu-dG) is a modified oligonucleotide. 2'-deoxy-2'-fluoro-modified oligonucleotides shows high nuclease resistant and retained exceptional binding affinity to the RNA targets .
|
-
- HY-W700549
-
-
- HY-138607
-
|
|
|
Phosphoramidites
Guanine
|
|
5'-O-DMT-2'-O-TBDMS-rI is a modified nucleoside. 5'-O-DMT-2'-O-TBDMS-rI can be used in the synthesis of deoxyribonucleic acid or nucleic acid.
|
-
- HY-W114886
-
-
- HY-W570893
-
|
|
|
Phosphoramidites
Guanine
|
|
DMT-LNA-G phosphoramidite is a phosphoramidite that can be used in the synthesis of oligonucleotides.
|
-
- HY-138609
-
-
- HY-154366
-
|
N1-Methylpseudouridine CEP
|
|
Phosphoramidites
Uracil
|
|
5'-DMT-2'-O-TBDMS-N1-Methyl-PseudoUridine-CE-Phosphoramidite is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
-
- HY-W091754
-
|
|
|
Phosphoramidites
Guanine
|
|
5'-O-Dmt-n2-isobutyryl-2'-o-methyl-d-guanosine is a nucleoside that is made using an oxime opening of the 5' position and a methylation at the 2' position. 5'-O-Dmt-n2-isobutyryl-2'-o-methyl-d-guanosine has been shown to have an affinity for tissues in a chemotactic assay.
|
-
- HY-W854187
-
|
5'-DMT-2'-OMe-rG(N-Ac) Phosphoramidite
|
|
Phosphoramidites
Guanine
|
|
2'-Ome-Ac-G (5'-DMT-2'-OMe-rG(N-Ac)) Phosporamiditeyes 2'-Ome-Ac-G (5'-DMT-2'-OMe-rG(N-Ac))Phosphoramidite.
|
-
- HY-W036167
-
|
|
|
Phosphoramidites
Adenine
|
|
DMT-2'-F-dA Phosphoramidite is a phosphoramidite that can be used in the synthesis of oligonucleotides.
|
- HY-153249
-
|
|
|
Phosphoramidites
Cytosine
|
|
DMT-2'-F-Cytidine Phosphoramidite is a phosphoramidite that can be used in the synthesis of oligonucleotides.
|
- HY-W018179
-
- HY-W579407
-
|
|
|
Phosphoramidites
Adenine
|
|
DMT-2'-OMe-dA(bz) phosphoramidite is a phosphoramidite that can be used in the synthesis of oligonucleotides.
|
- HY-153251
-
|
|
|
Phosphoramidites
Guanine
|
|
DMT-2'-O-Methylguanosine phosphoramidite is a phosphorite monomer that can be used in the synthesis of oligonucleotides.
|
- HY-153253
-
|
|
|
Phosphoramidites
Adenine
|
|
DMT-2'-O-Methyladenosine phosphoramidite is a phosphorite monomer that can be used in the synthesis of oligonucleotides.
|
- HY-W579408
-
|
|
|
Phosphoramidites
Adenine
|
|
DMT-2'-F-dA(bz) phosphoramidite is a phosphoramidite that can be used in the synthesis of oligonucleotides.
|
- HY-21713
-
|
|
|
Phosphoramidites
Cytosine
|
|
DMT-2'O-Methyl-rC(tac) Phosphoramidite is a phosphoramidite that can be used in the synthesis of oligonucleotides.
|
- HY-W783407
-
|
5'-DMT-2'-TBDMS-rG(N-Ac) Phosphoramidite
|
|
Phosphoramidites
Guanine
|
|
Ac-rG (5'-DMT-2'-TBDMS-rG(N-Ac)) Phosporamidite is an acetylated guanosine ribonucleotide.
|
- HY-W579410
-
|
|
|
Phosphoramidites
Adenine
|
|
DMT-2'-F-6-chloro-dA phosphoramidite is a phosphoramidite that can be used in the synthesis of oligonucleotides.
|
- HY-W048489
-
|
5'-O-(4,4'-Dimethoxytrityl)-2'-O-methoxyethyl-thymidine
|
|
Phosphoramidites
Thymine
|
|
DMT-2'-O-MOE-Tr (5'-O-(4,4'-Dimethoxytrityl)-2'-O-methoxyethyl-thymidine) is a nucleoside analog containing a dimethoxytrityl (DMT) group, commonly used in the synthesis of nucleic acids.
|
- HY-W013059A
-
|
L-DA-CE phosphoramidite
|
|
Phosphoramidites
Adenine
|
|
DMT-L-dA(bz) Phosphoramidite (L-DA-CE phosphoramidite; compound 20c) is typically used in the synthesis of DNA. DMT-L-dA(bz) Phosphoramidite can be used in studying DNA-drug interactions .
|
- HY-164252
-
|
5′-O-Trityl-2′-deoxy-2′-fluorouridine
|
|
Phosphoramidites
Uracil
|
|
DMT-2'-FU (5'-O-Trityl-2'-deoxy-2'-fluorouridine)Is with DMTProtecting Group (Protect 5'end), FLabeled uridine ribonucleotide.
|
- HY-138613
-
|
|
|
Phosphoramidites
Hypoxanthine
|
|
5'-O-DMT-2'-O-TBDMS-rI is a modified nucleoside. 5'-O-DMT-2'-O-TBDMS-rI can be used in the synthesis of deoxyribonucleic acid or nucleic acid.
|
- HY-154413
-
|
|
|
Phosphoramidites
Cytosine
|
|
DMT-2'-F-Bz-dC is a cytidine analog. Cytidine analogs have a mechanism of inhibiting DNA methyltransferases (such as Zebularine, HY-13420), and have potential anti-metabolic and anti-tumor activities .
|
- HY-49000
-
- HY-49210
-
|
|
|
Phosphoramidites
Guanine
|
|
DMT-locG(ib) Phosphoramidite is a phosphorite monomer that can be used in the synthesis of oligonucleotides.
|
- HY-138605
-
- HY-164249
-
|
|
|
Phosphoramidites
Guanine
|
|
DMT-rG(Ac)Is with DMTProtecting Group (Protect 5'end), acetylated guanosine ribonucleotide.
|
- HY-W793155
-
|
|
|
Phosphoramidites
Adenine
|
|
N6-Benzoyl-2'-deoxy-3'-O-DMT-adenosine is a nucleoside analog that is structurally related to the natural nucleotide adenosine. N6-Benzoyl-2'-deoxy-3'-O-DMT-adenosine is an activator of ribonucleotide reductase, which converts ribonucleosides to deoxyribonucleosides.
|
- HY-138600
-
- HY-W008848A
-
|
|
|
Phosphoramidites
Guanine
|
|
DMT-L-dG(ib) Phosphoramidite (Compound 20D) is a nucleoside phosphoramidite that can be used for nucleotide assembly on solid supports .
|
- HY-138604
-
- HY-W048494
-
|
N4-Benzoyl-5-methyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-methoxyethyl-cytidine
|
|
Phosphoramidites
Cytosine
|
|
N4-Bz-5-Me-DMT-2'-O-MOE-Cr (N4-Benzoyl-5-methyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-methoxyethyl-cytidine) is a nucleoside analog containing a dimethoxytrityl (DMT) group, commonly used in the synthesis of nucleic acids.
|
- HY-138614
-
- HY-138611
-
- HY-138612
-
- HY-171114
-
|
|
|
Cationic Lipids
|
|
DMT7 is an ionizable cationic lipid (pKa = 6.5) that can be used to generate lipid nanoparticles (LNPs) for delivery of mRNA and anticancer drugs in the body .
|
- HY-138598
-
|
|
|
Nucleoside Analogs
Guanosine
|
|
5'-O-TBDMS-dG is a modified nucleoside. 5'-O-DMT-2'-O-TBDMS-rI can be used in the synthesis of deoxyribonucleic acid or nucleic acid.
|
- HY-W425093
-
|
|
|
Phosphoramidites
Thymine
|
|
(S)-DMT-glycidol-T is a Glycidol-Thymine complex with a dimethoxytrityl (DMT) protecting group.
|
- HY-W1121791
-
|
|
|
Phosphoramidites
Uracil
|
|
DMT-2'O-TC-rU Phosphoramidite is a phosphoramidite that can be used in the synthesis of oligonucleotides.
|
- HY-43049
-
|
Bz-rA Phosphoramidite enantiomer
|
|
Phosphoramidites
Adenine
|
|
DMT-2'O-TBDMS-rA(bz) Phosphoramidite enantiomer is a phosphoramidite that can be used in the synthesis of oligonucleotides.
|
- HY-177478
-
|
|
|
Phosphoramidites
Adenine
|
|
DMT-2′OTBS-adenosine(OTBS, TOMSE)-phosphoramidite is a phosphoramidite that can be used in the synthesis of oligonucleotides.
|
- HY-W1121775
-
|
|
|
Phosphoramidites
Cytosine
|
|
DMT-2'O-TC-rC(ac) Phosphoramidite is a phosphoramidite that can be used in the synthesis of oligonucleotides.
|
- HY-W1121763
-
|
|
|
Phosphoramidites
Adenine
|
|
DMT-2'O-TC-rA(bz) Phosphoramidite is a phosphoramidite that can be used in the synthesis of oligonucleotides.
|
- HY-W1121774
-
|
|
|
Phosphoramidites
Guanine
|
|
Dmt-2'o-tc-rg(ib) phosphoramidite is a phosphoramidite that can be used in the synthesis of oligonucleotides.
|
- HY-W1130289
-
- HY-182217
-
|
|
|
Phosphoramidites
Cytosine
|
|
DMT-TBDMS-rC Benzoxazine phosphoramidite is a phosphoramidite and can be used for the synthesis of oligonucleotides.
|
- HY-D1884
-
- HY-W1130272
-
|
|
|
Phosphoramidites
Guanine
|
|
DMT-dG(dmf)-CE-Phosphoramidite is a phosphoramidite that can be used in the synthesis of oligonucleotides.
|
- HY-W1130268
-
|
|
|
Phosphoramidites
Adenine
|
|
DMT-dA(dma)-CE-Phosphoramidite is a phosphoramidite that can be used in the synthesis of oligonucleotides.
|
- HY-W1121767
-
- HY-W460666
-
|
|
|
Phosphoramidites
Guanine
|
|
5'-O-DMT-N2-Ibu-2'-OMe-G is a crucial intermediate for the synthesis of antisense oligonucleotides. 5'-O-DMT-N2-Ibu-2'-OMe-G is involved in constructing antisense oligonucleotides with specific sequences, which can bind complementarily to the targeted mRNA. 5'-O-DMT-N2-Ibu-2'-OMe-G blocks the translation process of mRNA, thereby inhibiting the expression of specific proteins and playing a role in regulating gene expression. 5'-O-DMT-N2-Ibu-2'-OMe-G is promising for research of genetic diseases and tumors .
|
- HY-177293
-
|
|
|
Phosphoramidites
Guanine
|
|
DMT-G-3'-Ome-(dmf) Phosphoramidite is a phosphoramidite that can be used in the synthesis of oligonucleotides.
|
- HY-177294
-
|
|
|
Phosphoramidites
Guanine
|
|
DMT-G-3'-F-(dmf) Phosphoramidite is a phosphoramidite that can be used in the synthesis of oligonucleotides.
|
- HY-177245
-
- HY-177336
-
|
|
|
Phosphoramidites
Uracil
|
|
2'-Deoxy-5'-O-DMT-isouridine-CE Phosphoramidite is a phosphoramidite that can be used in the synthesis of oligonucleotides.
|
- HY-171704
-
|
|
|
Phosphoramidites
Guanine
|
|
3'-O-DMT-α-L-threofuranosyl-G(iBu)-2'-CE-phosphoramidite is a phosphoramidite that can be used in the synthesis of oligonucleotides.
|
- HY-202974
-
|
|
|
Phosphoramidites
Cytosine
|
|
5-Me-DMT-2'-O-MOE-C(Ac)-CE-phosphoramidite is a phosphoramidite that can be used in the synthesis of oligonucleotides.
|
- HY-177333
-
|
|
|
Phosphoramidites
Cytosine
|
|
2'-Deoxy-5'-O-DMT-5-methylcytidine(NBz)-CE Phosphoramidite is a phosphoramidite that can be used in the synthesis of oligonucleotides.
|
- HY-173175
-
|
|
|
Phosphoramidites
Uracil
|
|
5'-O-DMT-2'-O-TBDMS-2-Thiouridine 3'-CE phosphoramidite is a building block of nucleic acid .
|
- HY-20140
-
|
5'-O-(4,4'-Dimethoxytrityl)thymidine
|
|
Phosphoramidites
Thymine
|
|
5'-O-DMT-dT (5'-O-(4,4'-Dimethoxytrityl)thymidine) is a nucleoside derivative which can be used in the preparation of oligonucleotides .
|
- HY-48873
-
|
|
|
Phosphoramidites
Uracil
|
|
5'-O-DMT-5-Ethynyl-2'-deoxyuridine 3'-CE phosphoramidite is a phosphorite monomer that can be used in the synthesis of oligonucleotides.
|
- HY-46369
-
|
|
|
Phosphoramidites
Uracil
|
|
1-p-Chlorobenzyl-1,2,3-triazole-5′-O-DMT-dU Phosphoramidite is a phosphorite monomer that can be used in the synthesis of oligonucleotides.
|
- HY-W782181
-
|
|
|
Phosphoramidites
Cytosine
|
|
2'-Deoxy-N4-DMF-5'-O-DMT-pseudoisocytidine 3'-CE Phosphoramidite is a phosphoramidite that can be used in the synthesis of oligonucleotides.
|
- HY-W087199
-
|
|
|
Phosphoramidites
Adenine
|
|
N6-Benzoyl-2'-deoxy-5'-O-DMT-a-adenosine 3'-CE phosphoramidite is a phosphorite monomer that can be used in the synthesis of oligonucleotides.
|
- HY-154955
-
|
|
|
Phosphoramidites
Cytosine
|
|
N4-Acetyl-2'-deoxy-3'-O-DMT-cytidine-5'-CE phosphoramidite is a phosphoramidite that can be used in the synthesis of oligonucleotides.
|
- HY-171938
-
|
|
|
Phosphoramidites
Cytosine
|
|
5-Aza-N6-benzoyl-5'-O-DMT-2'-deoxycytidine 3'-CE phosphoramidite is a phosphoramidite that can be used in the synthesis of oligonucleotides.
|
- HY-W114328
-
|
N-Acetyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-methylcytidine
|
|
Phosphoramidites
Cytosine
|
|
DMT-OMe-rC(Ac) (N-Acetyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-methylcytidine) is a nucleotide derivative that can be used to synthesize oligoribonucleotides .
|
- HY-182990
-
|
|
|
Phosphoramidites
Cytosine
|
|
N3-Methylcytidine phosphoramidite [5′-O-DMT2′-O-TBDMS-m3 CAc] is a phosphoramidite monomer. Phosphoramidites can be used in the synthesis of oligonucleotides .
|
- HY-152970
-
|
|
|
Phosphoramidites
Uracil
|
|
7'-O-DMT-morpholino uracil is a uridine analog. Uridine has potential antiepileptic effects, and its analogs can be used to study anticonvulsant and anxiolytic activities, as well as to develop new antihypertensive agents .
|
- HY-W008662
-
|
|
|
Phosphoramidites
Uracil
|
|
2'-Deoxy-5'-O-DMT-2'-fluorouridine, a nucleoside analogue, is a 5’-O-DMTr-5-FUDR derivative with potent anti-yellow fever (YFV) activity .
|
- HY-W1121766
-
|
|
|
Phosphoramidites
Uracil
|
|
5'-O-DMT-2'-O-[2-(Methylamino)-2-oxoethyl]-5-Me-uridine 3'-CE phosphoramidite is a phosphoramidite that can be used in the synthesis of oligonucleotides.
|
- HY-W726201
-
|
|
|
Phosphoramidites
Uracil
|
|
2'-Deoxy-5'-O-DMT-5-fluorouridine 3'-CE phosphoramidite is a nucleoside phosphoramidite analogue employed in oligonucleotide synthesis. This compound contributes to crafting therapeutic oligonucleotides for drugs targeting cancers.
|
- HY-104039
-
|
|
|
Phosphoramidites
Cytosine
|
|
2'-Deoxy-5'-O-DMT-5-methylcytidine is a cytidine analog. Cytidine analogs have a mechanism of inhibiting DNA methyltransferases (such as Zebularine, HY-13420), and have potential anti-metabolic and anti-tumor activities .
|
- HY-154019
-
|
|
|
Phosphoramidites
Cytosine
|
|
N4-Benzoyl-5'-O-DMT-5-methylcytidine is a cytidine analog. Cytidine analogs have a mechanism of inhibiting DNA methyltransferases (such as Zebularine, HY-13420), and have potential anti-metabolic and anti-tumor activities .
|
- HY-154410
-
|
|
|
Phosphoramidites
Uracil
|
|
5’-O-DMT-2’-deoxy-2’-fluoro-β-D-arabinouridine is a uridine analog. Uridine has potential antiepileptic effects, and its analogs can be used to study anticonvulsant and anxiolytic activities, as well as to develop new antihypertensive agents .
|
- HY-152978
-
|
|
|
Phosphoramidites
Cytosine
|
|
2'-Deoxy-5'-O-DMT-N4-Fmoc-5-methylcytidine is a cytidine analog. Cytidine analogs have a mechanism of inhibiting DNA methyltransferases (such as Zebularine, HY-13420), and have potential anti-metabolic and anti-tumor activities .
|
- HY-154309
-
|
|
|
Phosphoramidites
Adenine
|
|
3'-O-tert-Butyldimethylsilyl-5'-O-DMT-2'-deoxyadenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
- HY-154604
-
|
|
|
Phosphoramidites
Thymine
|
|
1-(2'-Deoxy-5'-O-DMT-2'-fluoro-b-D-arabinofuranosyl)thymine 3'-CE phosphoramidite is a thymidine analog. Analogs of this series have insertional activity towards replicated DNA. They can be used to label cells and track DNA synthesis .
|
- HY-154363
-
|
|
|
Phosphoramidites
|
|
3-Cyanovinyl-9-(5’-O-DMT-2’-deoxyribofuranosyl)carbazole is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
- HY-154267
-
|
|
|
Phosphoramidites
Uracil
|
|
5'-O-DMT-2-thio-2'-dU-3'-phosphoramidite is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
- HY-154450
-
|
|
|
Phosphoramidites
Cytosine
|
|
N4-Benzoyl-5’-O-DMT-3’-O-(2-methoxyethyl)-5-methylcytidine is a cytidine analog. Cytidine analogs have a mechanism of inhibiting DNA methyltransferases (such as Zebularine, HY-13420), and have potential anti-metabolic and anti-tumor activities .
|
- HY-154229
-
|
|
|
Phosphoramidites
Guanine
|
|
3’-O-DMT-N2-isobutyryl-2’-O-(2-methoxyethyl)guanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
- HY-154030
-
|
|
|
Phosphoramidites
Adenine
|
|
N6-Benzoyl-3'-deoxy-5'-O-DMT-3'-fluoroadenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
- HY-152979
-
|
|
|
Phosphoramidites
Cytosine
|
|
2'-Deoxy-5'-O-DMT-N4-Fmoc-5-methylcytidine 3'-CE-phosphoramidite is a cytidine analog. Cytidine analogs have a mechanism of inhibiting DNA methyltransferases (such as Zebularine, HY-13420), and have potential anti-metabolic and anti-tumor activities .
|
- HY-154441
-
|
|
|
Phosphoramidites
Cytosine
|
|
N4-Benzoyl-3'-O-DMT-2'-O-(2-methoxyethyl)-5-methylcytidine is a cytidine analog. Cytidine analogs have a mechanism of inhibiting DNA methyltransferases (such as Zebularine, HY-13420), and have potential anti-metabolic and anti-tumor activities .
|
- HY-154221
-
|
|
|
Phosphoramidites
Cytosine
|
|
N4-Benzoyl-2'-deoxy-5'-O-DMT-2',2'-difluorocytidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
- HY-154260
-
|
|
|
Phosphoramidites
Adenine
|
|
N6-Benzoyl-3'-O-DMT-2'-O-(2-methoxyethyl) adenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
- HY-154207
-
|
|
|
Phosphoramidites
Cytosine
|
|
2’-O-Acetyl-N4-benzoyl-5’-O-DMT arabinocytidine 3’-O-phosphoramidite is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
- HY-152988
-
|
|
|
Phosphoramidites
Guanine
|
|
N2-iso-Butyroyl-7'-O-DMT-morpholinoguanine is a guanosine analog. Some guanosine analogs have immunostimulatory activity. In some animal models, they also induce type I interferons, producing antiviral effects. Studies have shown that the functional activity of guanosine analogs is dependent on the activation of Toll-like receptor 7 (TLR7) .
|
- HY-152973
-
|
|
|
Phosphoramidites
Thymine
|
|
7'-O-DMT-morpholino thymine is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277) .
|
- HY-154350
-
|
|
|
Phosphoramidites
Guanine
|
|
5'-O-DMT-N2-isobutyryl-2'-O-propargylguanosine is a guanosine analog. Some guanosine analogs have immunostimulatory activity. In some animal models, they also induce type I interferons, producing antiviral effects. Studies have shown that the functional activity of guanosine analogs is dependent on the activation of Toll-like receptor 7 (TLR7) .
|
- HY-138589
-
|
|
|
Nucleoside Analogs
Guanosine
|
|
5'-O-TBDMS-dG is a modified nucleoside. 5'-O-DMT-2'-O-TBDMS-rI can be used in the synthesis of deoxyribonucleic acid or nucleic acid. 7-TFA-ap-7-Deaza-dG is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
- HY-154548
-
|
|
|
Phosphoramidites
Guanine
|
|
N2-iso-Butyroyl-5’-O-DMT-3’-O-(methoxyethyl)guanosine is a guanosine analog. Some guanosine analogs have immunostimulatory activity. In some animal models, they also induce type I interferons, producing antiviral effects. Studies have shown that the functional activity of guanosine analogs is dependent on the activation of Toll-like receptor 7 (TLR7) .
|
- HY-152984
-
|
|
|
Phosphoramidites
Adenine
|
|
N6-Benzoyl-7'-O-DMT-morpholino adenine is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277) .
|
- HY-W097792
-
|
5'-O-DMT-dU
|
|
Nucleoside Analogs
Uridine
|
|
5'-O-(4,4'-Dimethoxytrityl)-2'-deoxyuridine (5'-O-DMT-dU) is a competitive inhibitor of E. coli dUTP nucleotidohydrolase (dUTPase), with the Ki higher than 1000 μM. 5'-O-(4,4'-Dimethoxytrityl)-2'-deoxyuridine can be used in machine-assisted DNA synthesis by synthesizing nucleosidic phosphoramidite blocks .
|
- HY-W010702
-
|
N2-Isobutyryl-5′-O-(4,4′-dimethoxytrityl)-2′-deoxyguanosine
|
|
Phosphoramidites
Guanine
|
|
5'-O-DMT-N2-ibu-dG (N2-Isobutyryl-5′-O-(4,4′-dimethoxytrityl)-2′-deoxyguanosine) is a protected 2'-deoxyguanosine derivative with 5'-O-(4,4'-dimethoxytriphenylmethyl) and N2-isobutyryl protecting groups, and serves as a building block in oligonucleotide synthesis .
|
- HY-154464
-
|
|
|
Phosphoramidites
Guanine
|
|
N2-iso-Butyroyl-5'-O-DMT-3'-deoxy-3'-fluoroguanosine is a guanosine analog. Some guanosine analogs have immunostimulatory activity. In some animal models, they also induce type I interferons, producing antiviral effects. Studies have shown that the functional activity of guanosine analogs is dependent on the activation of Toll-like receptor 7 (TLR7) .
|
- HY-45281
-
|
|
|
Phosphoramidites
Adenine
|
|
N6-Benzoyl-5'-O-DMT-3'-O-methyladenosine 3'CE-phosphoramidite is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277) .
|
- HY-152983
-
|
|
|
Phosphoramidites
Adenine
|
|
2'-Deoxy-5'-O-DMT-N6-Fmoc-adenosine 3'CE-phosphoramidite is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277) .
|
- HY-154419
-
|
|
|
Phosphoramidites
Adenine
|
|
N6-Benzoyl-2'-O-tert-butyldimethylsilyl-3'-O-DMT-adenosine is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277) .
|
- HY-154339
-
|
|
|
Phosphoramidites
Adenine
|
|
N4-Benzoyl-5'-O-DMT-2'-O-propargyl adenosine is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277) .
|
- HY-W141392
-
|
|
|
Phosphoramidites
Hypoxanthine
|
|
2'-Fluoro-5'-O-DMT-2'-deoxyinosine-3'-CE-phosphoramidite is a hypoxanthine analog. Hypoxanthine is a kind of purine base mainly present in muscle tissue. And it is a metabolite produced by purine oxidase acting on xanthine. Hypoxanthine has typical anti-inflammatory effects and is a potential endogenous poly(ADP-ribose) polymerase (PARP) inhibitor. It is cytoprotective by inhibiting PAPR activity, inhibiting peroxynitrite-induced mitochondrial depolarization and secondary superoxide production. Hypoxanthine can also be used as an indicator of hypoxia .
|
- HY-W392836
-
|
|
|
Phosphoramidites
Hypoxanthine
|
|
2'-O-Methyl-5'-O-dmt-inosine-3'-CE-phosphoramidite is a hypoxanthine analog. Hypoxanthine is a kind of purine base mainly present in muscle tissue. And it is a metabolite produced by purine oxidase acting on xanthine. Hypoxanthine has typical anti-inflammatory effects and is a potential endogenous poly(ADP-ribose) polymerase (PARP) inhibitor. It is cytoprotective by inhibiting PAPR activity, inhibiting peroxynitrite-induced mitochondrial depolarization and secondary superoxide production. Hypoxanthine can also be used as an indicator of hypoxia .
|
- HY-W010706
-
|
5'-O-DMT-N4-Bz-dC
|
|
Nucleoside Analogs
Cytidine
|
|
N4-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxycytidine (5'-O-DMT-N4-Bz-dC) can be used for synthesis oligodeoxynucleotides containing a 3'-S-phosphorothiolate (3'-PS) linkage. N4-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxycytidine is an useful tool for probing enzyme-catalyzed cleavage processes in DNA .
|
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