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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
95 Results for "
FOS
" in MedChemExpress (MCE) Product Catalog:
Products (95)
95 Results for "FOS" in MCE Product Catalog:
109
109 Publications Verification
Research Areas:
T-5224 is a transcription factor c-Fos/activator protein (AP)-1 inhibitor with anti-inflammatory effects, which specifically inhibits the DNA binding activity of c-Fos/c-Jun without affecting other transcription factors. T-5224 inhibits the IL-1β-induced up-regulation of Mmp-3, Mmp-13 and Adamts-5 transcription .
4
Category:
Flavonoids Ginkgoaceae Phenols Polyphenols Plants Disease Research Fields Inflammation/Immunology Ginkgo biloba Biflavones
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2
2
1
1 Cited Publications
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Latanoprost acid, an analog of prostaglandin (PG) F2α, is an selective prostanoid receptor (FP) agonist that specifically activates the FP-PG receptor . Latanoprost acid inhibits RANKL-induced osteoclastgenesis and function by inhibiting ERK, AKT, JNK, and p38 cascade, following by the c-fos/NFATc1 pathway. Latanoprost acid is a medication which works to lower pressure inside the eyes .
1
1 Cited Publications
Cat. No.: HY-N0805A
CAS No.: 18649-93-9
Category:
Triterpenes Alisma plantago-aquatica Linn. Terpenoids Metabolic Disease Plants Alismataceae Disease Research Fields
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Cat. No.: HY-P10408
CAS No.: 1906866-53-2
Research Areas:
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Schizophyllan (SPG) is an orally active extracellular β-glucan produced by the fungus Schizophyllum commune. Schizophyllan improves mitochondrial function and protects against metabolic liver injury by activating the SIRT3 pathway. Schizophyllan inhibits osteoclastogenesis and promotes osteoblast differentiation by suppressing the phosphorylation of JNK/p38, as well as downregulating PGC1β/PPARγ, c-Fos and NFATc1. Recognized via Dectin-1, schizophyllan enables precise delivery of oligonucleotide drugs and antigens to antigen-presenting cells, thus holding great potential in the treatment of inflammatory diseases and vaccine development .
Cat. No.: HY-N5048
CAS No.: 122965-41-7
Synonyms: 6'-O-Galloyl paeoniflorin
Cat. No.: HY-P10927A
Synonyms: BRINP2-related peptide TFA
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Cat. No.: HY-B1052
CAS No.: 21498-08-8
Synonyms: Baq-168; MDL-14042
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Lofexidine hydrochloride (Baq-168) is an orally active agonist of the imidazoline I1 receptor (imidazoline I1 receptor) (Ki: 1.9 nM) and α2-adrenergic receptor (α2-adrenergic receptor). Lofexidine hydrochloride binds to the α2A-adrenergic receptor, reduces sympathetic outflow, lowers blood pressure, and exhibits vasoconstrictive effects. Lofexidine hydrochloride regulates the expression of c-fos and alleviates opioid withdrawal symptoms. Lofexidine hydrochloride is applicable to research on opioid addiction and withdrawal .
Cat. No.: HY-P10927
Synonyms: BRINP2-related peptide
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Cat. No.: HY-N6836
CAS No.: 62512-21-4
Category:
Polysaccharides Gramineae Other Diseases Plants Disease Research Fields Saccharum officinarum Saccharides
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Cat. No.: HY-106584
CAS No.: 89419-40-9
Synonyms: Clospipramine
Research Areas:
Mosapramine (Clospipramine) is an orally active antipsychotic agent and one of the metabolites of Clocapramine (HY-B2073) after oral absorption. Mosapramine exerts its effects by specifically binding to striatal dopamine D2 receptors and frontal lobe 5-HT2 receptors, with a D2/5-HT2 receptor occupancy ratio of 7.4. Mosapramine induces typical neuropharmacological responses in rat brain regions, including extrapyramidal symptoms, hyperprolactinemia, increased salivation, constipation, and upregulated Fos protein expression. Mosapramine also features a reduced incidence of weight loss. Mosapramine is applicable to research related to schizophrenia .
Cat. No.: HY-N6835
CAS No.: 143625-74-5
Category:
Polysaccharides Gramineae Other Diseases Plants Disease Research Fields Saccharum officinarum Saccharides
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Cat. No.: HY-B1052A
CAS No.: 31036-80-3
Synonyms: Baq-168 free base; MDL-14042 free base
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Lofexidine (Baq-168 free base) is an orally active agonist of the imidazoline I1 receptor (imidazoline I1 receptor) (Ki: 1.9 nM) and α2-adrenergic receptor (α2-adrenergic receptor). Lofexidine binds to the α2A-adrenergic receptor, reduces sympathetic outflow, lowers blood pressure, and exhibits vasoconstrictive effects. Lofexidine regulates the expression of c-fos and alleviates opioid withdrawal symptoms. Lofexidine is applicable to research on opioid addiction and withdrawal .
Cat. No.: HY-N6837
CAS No.: 62512-20-3
Category:
Polysaccharides Gramineae Other Diseases Plants Disease Research Fields Saccharum officinarum Saccharides
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Cat. No.: HY-A0116A
CAS No.: 951393-55-8
Synonyms: Trandolaprilat hydrate; RU 44403 hydrate
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
