383 Results for "

Indoles

" in MedChemExpress (MCE) Product Catalog:
Products (383)

383 Results for "Indoles" in MCE Product Catalog:

24
24 Publications Verification
Cat. No.: HY-18569A
CAS No.: 6505-45-9
Synonyms: Indole-3-acetic acid sodium; 3-IAA sodium
3-Indoleacetic acid (Indole-3-acetic acid) sodium is an IAA hormone and growth regulator that can promote plant nutritional growth through processes such as cell expansion, differentiation, morphogenesis, and organogenesis .
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18
18 Cited Publications
Cat. No.: HY-N0170
CAS No.: 700-06-1
Synonyms: Indole-3-methanol
Indole-3-carbinol (I3C) inhibits NF-κB activity and also is an Aryl hydrocarbon receptor (AhR) agonist, and an inhibitor of WWP1 (WW domain-containing ubiquitin E3 ligase 1).
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16
16 Cited Publications
Cat. No.: HY-113099
CAS No.: 1821-52-9
Purity:  99.99%
Synonyms: Indole-3-lactic acid
Indolelactic acid (Indole-3-lactic acid) is a tryptophan (Trp) catabolite in Azotobacter vinelandii cultures. Indolelactic acid has anti-inflammation and potential anti-viral activity .
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14
14 Cited Publications
Cat. No.: HY-N0117
CAS No.: 479-41-4
Synonyms: Couroupitine B; Indigo red; Indigopurpurin
Indirubin (Couroupitine B) is a bis-indole alkaloid and has emarkable anticancer activity against chronic myelocytic leukemia .
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11
11 Cited Publications
Cat. No.: HY-N6778
CAS No.: 57186-25-1
Paxilline is an indole alkaloid mycotoxin derived from Penicillium paxilli, which effectively inhibits the BK channel through a channel-blocking mechanism. Paxilline also inhibits sarco/endoplasmic reticulum Ca 2+-stimulated ATPase (SERCA), with IC50 values ranging from 5 μM to 50 μM for different SERCA isoforms. Paxilline exhibits significant anticonvulsant and neuroprotective effects, as well as certain antioxidant activity .
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8
8 Cited Publications
Cat. No.: HY-N6607
CAS No.: 13220-57-0
Tryptanthrin is an indole quinazoline that could be an alkaloid from indigo-bearing plants. Tryptanthrin is a potent and orally active cellular Leukotriene (LT) biosynthesis inhibitor. Tryptanthrin has anticancer activity. Tryptanthrin suppresses the expression levels of NOS1, COX-2, and NF-κB and regulates the expression levels of IL-2, IL-10, and TNF-α .
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7
7 Cited Publications
Cat. No.: HY-147216
CAS No.: 3103525-82-9
Purity:  99.77%
Target:  

Lactate Dehydrogenase

Research Areas:  

Cancer

AXKO-0046, indole derivative, is an uncompetitive Lactate dehydrogenase B (LDHB) selective inhibitor.AXKO-0046 has LDHB inhibitory activity with an EC50 value of 42 nM.AXKO-0046 can be used for the research of cancer metabolism .
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7
7 Cited Publications
Cat. No.: HY-147216A
Purity:  99.68%
AXKO-0046 dihydrochloride, indole derivative, is an uncompetitive Lactate dehydrogenase B (LDHB) selective inhibitor. AXKO-0046 dihydrochloride has LDHB inhibitory activity with an EC50 value of 42 nM. AXKO-0046 dihydrochloride can be used for the research of cancer metabolism .
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7
7 Cited Publications
Cat. No.: HY-112730
CAS No.: 6266-66-6
Purity:  99.70%
Synonyms: 2-(1H-Indol-3-yl)-4-oxo-4-phenyl-butyric acid
Target:  

Phytohormone

Research Areas:  

Others

PEO-IAA is an indole-3-acetic acid (IAA) antagonist. PEO-IAA is an auxin antagonist that binds to transport inhibitor response 1/auxin signaling F-box proteins (TIR1/AFBs).
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4
4 Cited Publications
Cat. No.: HY-W007376
CAS No.: 487-89-8
Synonyms: 3-Formylindole
Indole-3-carboxaldehyde (3-Formylindole), a banlangen extract, is the product of the oxidative degradation of indole-3-acetic acid (IAA) by crude enzyme preparations from etiolated pea seedlings. Indole-3-carboxaldehyde is a biochemical used to prepare analogs of the indole phytoalexin cyclobrassinin. Indole-3-carboxaldehyde also enhances the epithelial barrier and anti-inflammatory activity in the intestinal tract .
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4
4 Cited Publications
Cat. No.: HY-116425
CAS No.: 132-66-1
Purity:  99.97%
Synonyms: Alanap 1
Research Areas:  

Others

N-1-Naphthylphthalamic acid (Alanap 1) is a modulator of polar auxin transport that competes with auxin (indole-3-acetic acid, IAA) for membrane binding sites. N-1-Naphthylphthalamic acid also disrupts maize leaf initiation, KNOX protein regulation, and leaf margin formation .
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3
3 Cited Publications
Cat. No.: HY-W028393
CAS No.: 392-12-1
Indole-3-pyruvic acid, a keto analogue of tryptophan, is an orally active AHR agonist. Indole-3-pyruvic acid has antioxidant properties, and can be used in the research of inflammation, anxiety .
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3
3 Cited Publications
Cat. No.: HY-W001132
CAS No.: 120-72-9
Indole is an aromatic, heterocyclic, organic compound which widely distributed in the natural environment and can be produced by a variety of bacteria. Indole regulates various aspects of bacterial physiology, including spore formation, plasmid stability, resistance to drugs, biofilm formation, and virulence as an intercellular signal molecule .
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2
2 Cited Publications
Cat. No.: HY-40161
CAS No.: 771-50-6
Indole-3-carboxylic acid is an orally active urinary indolic tryptophan metabolite. Indole-3-carboxylic acid is a mediator of priming against Plectosphaerella cucumerina. Indole-3-carboxylic acid enhances the anti-colorectal cancer potency of Doxorubicin (HY-15142A) by inducing cell senescence. Indole-3-carboxylic acid can be used in liver disease research .
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2
2 Cited Publications
Cat. No.: HY-W016784
CAS No.: 879-37-8
Indole-3-acetamide is a biosynthesis intermediate of 3-Indoleacetic acid (HY-18569). Indole-3-acetic acid is the most common natural plant growth hormone of the auxin class .
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2
2 Cited Publications
Cat. No.: HY-33893
CAS No.: 22259-53-6
Indole-3-methanamine is an indole derivative, stress-related metabolite, and also a biosynthetic precursor of Gramine (HY-N0166). The accumulation level of Indole-3-methanamine increases in susceptible barley varieties infected with Bipolaris sorokiniana. Indole-3-methanamine can be used in studies related to barley spot blotch .
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2
2 Cited Publications
Cat. No.: HY-136199
CAS No.: 352554-02-0
Purity:  98.15%
Target:  

Sirtuin CMV

Research Areas:  

Infection

SIRT1-IN-1 is a selective SIRT1 inhibitor with an IC50 of 0.205 μM. SIRT1-IN-1 inhibits SIRT2 with an IC50 of 11.5 μM . SIRT1-IN-1, a indole, is a cytomegalovirus (CMV) inhibitors and has antiviral activity .
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2
2 Cited Publications
Cat. No.: HY-N2197
CAS No.: 35467-43-7
Hirsuteine is an indole alkaloid extracted from Uncaria rhynchophylla. Hirsuteine non-competitively antagonizes nicotine-mediated dopamine release by blocking ion permeation through nicotinic receptor channel complexes .
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2
2 Cited Publications
Cat. No.: HY-N2179
CAS No.: 487-58-1
Hypaphorine is an indole found in Caragana korshinskii. Hypaphorine has neurological and glucose-lowering effects. Hypaphorine prevents Lipopolysaccharides (LPS) (HY-D1056)-mediated acute lung injury (ALI) and proinflammatory response via inactivating the p38/JNK signaling pathway by upregulating DUSP1 .
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2
2 Cited Publications
Cat. No.: HY-W014971
CAS No.: 343-94-2
Tryptamine hydrochloride belongs to the class of indole alkaloids and is a derivative of the amino acid tryptophan. Tryptamine hydrochloride is psychoactive and acts as a neurotransmitter in the body, affecting mood, perception and cognition. In its hydrochloride form, Tryptamine hydrochloride hydrochloride, it is commonly used as a research chemical and as a starting material for the synthesis of other organic compounds. It can also occur naturally in certain plants and animals, including fungi and mammals. Due to the psychoactive properties of Tryptamine hydrochloride and its derivatives, its use and possession are controlled substances in many countries.
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