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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
183 Results for "
L3
" in MedChemExpress (MCE) Product Catalog:
Products (183)
183 Results for "L3" in MCE Product Catalog:
21
21 Publications Verification
Cat. No.: HY-18637
CAS No.: 668467-91-2
Target:
Research Areas:
LDN-57444 is a reversible, competitive and site-directed inhibitor of ubiquitin C-terminal hydrolase L1 (UCH-L1), with an IC50 of 0.88 μM and a Ki of 0.40 μM; LDN-57444 also suppresses UCH-L3 activity, with an IC50 of 25 μM.
12
12 Cited Publications
Cat. No.: HY-17596
CAS No.: 57808-65-8
Closantel is a halogenated salicylanilide with a potent anti-parasitic activity. Closantel is a potent and highly specific Onchocerca volvulus chitinase (OvCHT1) inhibitor with an IC50 of 1.6 μM and a Ki of 468 nM. Closantel inhibits the O. volvulus L3 to L4 molt of developing .
12
12 Cited Publications
Cat. No.: HY-17596A
CAS No.: 61438-64-0
Closantel sodium is a halogenated salicylanilide with a potent anti-parasitic activity. Closantel sodium is a potent and highly specific Onchocerca volvulus chitinase (OvCHT1) inhibitor with an IC50 of 1.6 μM and a Ki of 468 nM. Closantel sodium inhibits the O. volvulus L3 to L4 molt of developing .
7
7 Cited Publications
Cat. No.: HY-18638
CAS No.: 30675-13-9
Synonyms: 4,5,6,7-Tetrachloroindan-1,3-dione
Target:
Research Areas:
TCID (4,5,6,7-Tetrachloroindan-1,3-dione) is a potent and selective neuronal ubiquitin C-terminal hydrolase (UCH-L3) inhibitor with an IC50 of 0.6 μM . TCID diminishes glycine transporter GlyT2 ubiquitination in brainstem and spinal cord primary neurons .
4
4 Cited Publications
Cat. No.: HY-P7845
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Ym1; Chi3L3; ChiL3; Secreted protein Ym1; Eosinophil chemotactic cytokine; ECF-L; Chitinase-3-like protein 3; Beta-N-acetylhexosaminidase Ym1; EC:3.2.1.52; Chitinase-like protein 3; rMuChitinase-like protein 3/YM1, His
Species:
Mouse
Source:
HEK293
2
2 Cited Publications
Cat. No.: HY-W050031
CAS No.: 6168-83-8
Synonyms: (S)-β-Hydroxybutanoic acid; L-(+)-3-Hydroxybutyric acid; L-β-Hydroxybutyric acid
Category:
Microorganisms Ketones, Aldehydes, Acids Other Diseases Endogenous metabolite Disease Research Fields
Target:
2
2 Cited Publications
Cat. No.: HY-P701317
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: TFAM; Alternative Protein TFAM; Prev. TCF6L2; MTDPS15; Prev. TCF6; TCF6L1; Mitochondrial Transcription Factor 1; TCF6L3; Transcription Factor 6; MTTF1; Transcription Factor 6-Like 2 (Mitochondrial Transcription Factor); MTTFA; Mitochondrial Transcription Factor A; TCF-6; Transcription Factor 6-Like 1; MtTF1; Transcription Factor 6-Like 3; MtTFA; Transcription Factor 6-Like 2; Transcription Factor A, Mitochondrial; TFAM Protein
Species:
Human
Source:
E. coli
1
Target:
1
1 Cited Publications
Cat. No.: HY-P71115
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: UCHL3; Ubiquitin C-Terminal Hydrolase L3; Ubiquitin Carboxyl-Terminal Esterase L3 (Ubiquitin Thiolesterase); Ubiquitin Carboxyl-Terminal Hydrolase Isozyme L3; Ubiquitin Thioesterase L3; Ubiquitin Thiolesterase; UCH-L3; Ubiquitin Carboxyl-Terminal Hydrolas
Species:
Human
Source:
E. coli
1
1 Cited Publications
Cat. No.: HY-P79451
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: UBE2L3; Ubiquitin Conjugating Enzyme E2 L3; UBCH7; Ubiquitin-Conjugating Enzyme E2 L3; E2 Ubiquitin-Conjugating Enzyme L3; Ubiquitin-Conjugating Enzyme E2-F1; Ubiquitin Carrier Protein L3; Ubiquitin-Protein Ligase L3; L-UBC; Ubiquitin-Conjugating Enzyme E
Species:
Human
Source:
E. coli
1
1 Cited Publications
Cat. No.: HY-P790035
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: DNASE1L3; Deoxyribonuclease Gamma; Deoxyribonuclease 1L3; Liver And Spleen DNase; DNAS1L3; DNase I-Like 3; LSD; DNaseY; DNase Gamma; DHP2; LS-DNase; Deoxyribonuclease I-Like III; D3; Deoxyribonuclease I Like 3; DNase I Homolog Protein DHP2; DNase I Homolo
Species:
Mouse
Source:
E. coli
1
1 Cited Publications
Cat. No.: HY-P83756
Synonyms: CD 4 antibody;
CD4 (L3T4) antibody;
CD4 antibody;
CD4 antigen (p55) antibody;
CD4_HUMAN antibody;
CD4mut antibody;
L3T4 antibody;
Leu3 antibody;
Ly-4 antibody;
Lymphocyte antigen CD4 antibody;
MGC165891 antibody;
OTTHUMP00000238897 antibody;
p55 antibody;
T cell antigen T4 antibody;
W3/25 antibody
1
1 Cited Publications
Cat. No.: HY-P701316
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: TFAM; Alternative Protein TFAM; Prev. TCF6L2; MTDPS15; Prev. TCF6; TCF6L1; Mitochondrial Transcription Factor 1; TCF6L3; Transcription Factor 6; MTTF1; Transcription Factor 6-Like 2 (Mitochondrial Transcription Factor); MTTFA; Mitochondrial Transcription
Species:
Mouse
Source:
E. coli
1
1 Cited Publications
Cat. No.: HY-P70742
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: SIGLEC15; Sialic Acid-Binding Ig-Like Lectin 15; Prev. CD33L3; SIGLEC-15; CD33 Antigen-Like 3; Sialic Acid Binding Ig-Like Lectin 15; HsT1361; Siglec-15; Sialic Acid Binding Ig Like Lectin 15; CD33 Molecule-Like 3
Species:
Human
Source:
HEK293
Cat. No.: HY-162943
Target:
Research Areas:
P60-L3-VHL is a PROTAC degrader targeting Foxp3. P60-L3-VHL triggers the ubiquitination modification of Foxp3 by conjugating the Foxp3-targeting peptide P60 with the VHL E3 ubiquitin ligase ligand via a long linker, and mediates protein degradation through the proteasome pathway. P60-L3-VHL blocks the nuclear translocation of Foxp3, relieves the transcriptional inhibition of IL2 and IFN-γ, and inhibits the differentiation of iTreg cells. P60-L3-VHL is applicable to cancer-related research .
Cat. No.: HY-N0562
CAS No.: 218916-52-0
Synonyms: Euphorbia factor L3
Category:
Terpenoids Leptochloa chinensis (Linn.) Nees Diterpenoids Plants Gramineae Extract Disease Research Fields Cancer
Target:
Synonyms: R-L3
Target:
Research Areas:
L-364,373 (R-L3) is a voltage-gated Kv7.1 (KCNQ1)/mink channels activator. L-364,373 activates Iks (slow delayed rectifier potassium current) and shortens action potential duration in guinea pig cardiac myocytes, and suppresses early afterdepolarizations in rabbit ventricular myocytes .
Cat. No.: HY-I0393
CAS No.: 22951-96-8
Synonyms: L-3-(2-Thienyl)alanine
Target:
Research Areas:
Synonyms: IONIS ANGPT-L3Rx sodium; ISIS 703802 sodium
Target:
Research Areas:
Vupanorsen (sodium) is an N-acetyl galactosamine-conjugated antisense oligonucleotide that inhibits Angiopoietin-like 3 (ANGPTL3) protein synthesis. Vupanorsen (sodium) lowers triglycerides and atherogenic lipoproteins.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
