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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
24 Results for "
LPS-stimulated macrophages
" in MedChemExpress (MCE) Product Catalog:
Products (24)
24 Results for "LPS-stimulated macrophages" in MCE Product Catalog:
162
162 Publications Verification
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JSH-23 is an NF-κB inhibitor which inhibits NF-κB transcriptional activity with an IC50 of 7.1 μM in lipopolysaccharide (LPS)-stimulated macrophages RAW 264.7. JSH-23 inhibits nuclear translocation of NF-κB p65 without affecting IκBα degradation .
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Category:
Cardiovascular Disease Solanum lycopersicum L. Plants Solanaceae Disease Research Fields Steroids
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2
2 Cited Publications
Cat. No.: HY-N0577
CAS No.: 26544-34-3
Synonyms: Apigenin 7-O-apiosylglucoside; Apigenin 7-(2-O-apiosylglucoside)
Category:
Flavonoids Flavones Phenols Polyphenols Plants Umbelliferae Disease Research Fields Baccharis sarothroides A.Gray Inflammation/Immunology
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1 Cited Publications
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Natural Products Plants Brassicaceae Disease Research Fields Inflammation/Immunology Rorippa indica (L.) Hiern
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Cat. No.: HY-W001174
CAS No.: 490-78-8
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Cat. No.: HY-N4233
CAS No.: 30557-81-4
Category:
Terpenoids Sesquiterpenes Plants Umbelliferae Disease Research Fields Inflammation/Immunology Echinacea angustifolia DC.
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Cat. No.: HY-N1912
CAS No.: 869807-57-8
Category:
Acanthaceae Simsia foetida (Cav.) S.F.Blake Terpenoids Diterpenoids Plants Disease Research Fields Inflammation/Immunology
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Cat. No.: HY-N7422
CAS No.: 16836-31-0
Synonyms: ent-Kauran-16β,17-diol
Category:
Liliaceae Terpenoids Diterpenoids Plants Disease Research Fields Inflammation/Immunology Fritillaria cirrhosa
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Cat. No.: HY-13982R
CAS No.: 749886-87-1
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JSH-23 (Standard) is the analytical standard of JSH-23. This product is intended for research and analytical applications. JSH-23 is an NF-κB inhibitor which inhibits NF-κB transcriptional activity with an IC50 of 7.1 μM in lipopolysaccharide (LPS)-stimulated macrophages RAW 264.7. JSH-23 inhibits nuclear translocation of NF-κB p65 without affecting IκBα degradation .
Cat. No.: HY-W573700
CAS No.: 520-43-4
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Cat. No.: HY-174144
CAS No.: 2851993-73-0
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RJG-2036 is a potent covalent inhibitor of human prostaglandin reductase 2 (PTGR2)(IC50=100 nM). RJG-2036 inhibits NADPH-dependent reduction, significantly reducing secretion of proinflammatory cytokines like TNF-α and multiple eicosanoids in LPS-stimulated THP-1 macrophages. RJG-2036 is promising for research of inflammatory diseases .
Cat. No.: HY-N3385
CAS No.: 129314-37-0
Synonyms: 7-O-Methyllicorisoflavan B
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Cat. No.: HY-N1117
CAS No.: 139101-67-0
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Dieugenol is a neolignan that has been found in N. leucantha and has antioxidative and antiprotozoal activities. It inhibits the formation of thiobarbituric acid reactive substances (TBARS) and scavenges superoxide anions, but not hydroxyl radicals, in cell-free assays. It has anti-trypanosomal activity against T. cruzi amastigotes and trypomastigotes (IC50s=15.1 and 11.5 μM, respectively) but is cytotoxic to NCTC L-929 fibroblasts with a 50% cytotoxic concentration (CC50) value of 58.2 μM.2 Dieugenol (15 μM) disrupts the integrity of the T. cruzi trypomastigote plasma membrane but does not induce the production of reactive oxygen species (ROS) in trypomastigotes or LPS-stimulated and unstimulated isolated mouse peritoneal macrophages.
Cat. No.: HY-163368
CAS No.: 1432508-73-0
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HDAC6-IN-34 (compound 21) is an oral active and selective HDAC6 inhibitor with the IC50 of 18 nM. HDAC6-IN-34 increases the acetylation level of tubulin without affecting histone acetylation in cutaneous T-cell lymphoma cells and inhibits TNF-α secretion in LPS (HY-D1056)-stimulated macrophage cells. HDAC6-IN-34 shows excellent anti-arthritic efficacy in rat .
Cat. No.: HY-N17528
CAS No.: 268541-25-9
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Cat. No.: HY-N13781
CAS No.: 1152441-87-6
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Cat. No.: HY-N1192
CAS No.: 315236-68-1
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
