31 Results for "

RACK

" in MedChemExpress (MCE) Product Catalog:
Products (31)

31 Results for "RACK" in MCE Product Catalog:

5
5 Cited Publications
Referencia número: HY-P0154
No. CAS: 182683-50-7
Synonyms: ε-V1-2; EAVSLKPT
Target:  

PKC

Áreas de investigación:  

Inflammation/Immunology

Epsilon-V1-2 (ε-V1-2), a PKCε-derived peptide, is a selective PKCε inhibitor. Epsilon-V1-2 inhibits the translocationof PKCε, but not α-, β-, and δPKC .
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2
2 Cited Publications
Referencia número: HY-N10335
No. CAS: 64761-48-4
Harringtonolide is a potent RACK1 inhibitor (IC50=39.66 μM in A375 cells). Harringtonolide inhibits the epithelial-mesenchymal transition (EMT) process and cell proliferation by affecting the interaction between FAK and RACK1. Harringtonolide has plant growth inhibitory, antiviral, anti-inflammatory, and antiproliferation activities .
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Referencia número: HY-141891
No. CAS: 1359431-16-5
Pureza:  98.28%
M435-1279 is a UBE2T inhibitor. M435-1279 inhibits the Wnt/β-catenin signaling pathway hyperactivation through blocking UBE2T-mediated degradation of RACK1 .
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Referencia número: HY-RS11595
Áreas de investigación:  

Others

RACK1 Human Pre-designed siRNA Set A contains three designed siRNAs for RACK1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Referencia número: HY-162254
No. CAS: 3032642-29-5
Target:  

EGFR Ack1

Áreas de investigación:  

Cancer

EGFR T790M/L858R/ACK1-IN-1 is a dual inhibitor of EGFR T790M/L858R and ACK1. IC50 values are 23 and 263 nM, respectively. EGFR T790M/L858R/ACK1-IN-1 can inhibit cell proliferation and has antitumor activity .
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Referencia número: HY-174975
Áreas de investigación:  

Cancer

JY-21 is a BRD4 PROTAC degrader active against both long and short BRD4 isoforms. JY-21 binds to TRIM28, RACK1, LMO7 and FUS to induce proteasomal degradation of BRD4 isoforms (DC50: 5.944 μM for long BRD4 isoform; 3.797 μM for short BRD4 isoform). JY-21 is applicable to research related to triple-negative breast cancer .
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Referencia número: HY-P1371
Synonyms: KKWKMRRNQFWIKIQRC CSVEIWD*
Target:  

PKC

Áreas de investigación:  

Others

Pseudo RACK1, a peptide, is a PKC agonist with homologous sequences of PKC. Pseudo RACK1 interacts selectively with β-PKC at an autoregulatory site (RACK-binding site) and activates it in the absence of PKC activators, following inducing PKC-mediated histone phosphorylation .
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Referencia número: HY-RS23221
Áreas de investigación:  

Others

Rack1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Rack1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Referencia número: HY-P3879
No. CAS: 149839-94-1
Synonyms: PKC βII (660-673)
Target:  

PKC

Áreas de investigación:  

Others

Protein Kinase C (660-673) (PKC βII (660-673)) is the PKC βII V5 peptide with RACK1-binding affinity .
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Referencia número: HY-115907A
No. CAS: 2915618-92-5
Target:  

Drug Isomer

Áreas de investigación:  

Cancer

(rac)-K20 is the racemate of K20, a KRas G12C inhibitor with an IC50 of 1.16 μM. K20 has antitumor activity .
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Referencia número: HY-169578
No. CAS: 904458-98-6
Target:  

PKC

Áreas de investigación:  

Cancer

PKC-IN-5 (Compound PKCe2054) is a PKC inhibitor. PKC-IN-5 prevents the interaction between PKCe and its adaptor protein RACK2 .
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Referencia número: HY-E0225
compounds
0.5 mL 96-Well Tube Rack, compliant with the industry-standard SBS (Society for Biomolecular Screening) specifications. This product features a sliding lock mechanism on the lid to prevent tube dislodgement. The side of the rack is equipped with an identifiable barcode for easy compound storage and retrieval. The matching tube (HY-E0224) is made from the same material as this tube, effectively preventing uneven expansion issues during freeze-thaw cycles.
Referencia número: HY-P0221B
Target:  

PACAP Receptor

Áreas de investigación:  

Endocrinology

PACAP (1-38) free acid TFA is an endogenous neuropeptide. PACAP (1-38) free acid TFA potently stimulates antral motility and somatostatin secretion, inhibits the secretion of gastrin and stimulates the release of vasoactive intestinal polypeptide, gastrin releasing peptide and substance P. PACAP (1-38) free acid TFA also enhances N-methyl-D-aspartate receptor function and expression of brain-derived neurotrophic factor through RACK1 .
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Referencia número: HY-RS16781
Áreas de investigación:  

Others

Rack1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Rack1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Referencia número: HY-P11803
No. CAS: 1041004-14-1
Target:  

PKC

Áreas de investigación:  

Neurological Disease

KAI-1678 is a selective protein kinase Cε (PKCε) inhibitor that competitively blocks the binding of PKCε to its anchoring protein RACK. KAI-1678 attenuates the responses of nociceptive neurons in rodent neuropathic pain models. KAI-1678 can be used in research related to moderate to severe postoperative pain, neuropathic pain, and postherpetic neuralgia .
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Referencia número: HY-P82059
Synonyms: H12.3; HLC-7; PIG21; RACK1; Gnb2-rs1

Host:  

Rabbit

Application:  

WB, IHC-P

Reactivity:  

Human, Mouse, Rat

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Referencia número: HY-P82059A
Synonyms: H12.3; HLC-7; PIG21; RACK1; Gnb2-rs1

Host:  

Rabbit

Application:  

WB, IHC-P

Reactivity:  

Human, Mouse, Rat

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Referencia número: HY-E0001

MCE® Cooling Rack can be used to prevent enzymes from becoming inactive as well as for PCR sample preparation, sample transport, and to slow thawing of frozen samples throughout your entire lab workflow.

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Referencia número: HY-181165
No. CAS: 3111225-79-4
Target:  

PKC SARS-CoV IFNAR

Áreas de investigación:  

Infection

SB2960 is a receptor for activated protein C kinase 1 (RACK1) binder with a human KD of 5.65 μM. SB2960 can promote stress granule (SG) formation and exhibit potent antiviral activity across diverse viral species. SB2960 suppresses viral replication with minimal cytotoxicity by modulating host antiviral immune responses. SB2960 increases the thermal stability of RACK1 and reduces SARS-CoV-2 N protein levels. SB2960 enhances type I interferon (IFN-β) expression and inhibits RIG-I, ISG56, and RANTES expression. SB2960 can be used for the research of virus infection .
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Referencia número: HY-E0224
compounds
0.5 mL Storage Tube, Three-Code Tube, External Thread with Screw Cap, Compatible with SBS- 96-Well Racks. This product is made from high-quality PP material, suitable for ultra-low temperature storage, with excellent weather resistance. Free from DNase and RNase, and can be sterilized by irradiation. The bottom of the tube features a unique QR code, while the side wall has a 1D linear barcode and directly readable numeric code, all three codes are identical and unique. The codes are laser-etched, scratch-resistant, not easy to fall off, and have high contrast for easy reading. The accompanying tube rack (HY-E0225) is made of the same material as the tube, effectively preventing uneven expansion issues during freeze-thaw cycles.