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Results for "

aryl

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Aryl Hydrocarbon Receptor (139) 5-HT Receptor (1) ADC Linker (5) Adenosine Receptor (3) Akt (3) Amino Acid Derivatives (1) Androgen Receptor (7) Angiotensin Receptor (1) Apoptosis (22) Autophagy (4) Bacterial (8) Bcl-2 Family (1) Bcr-Abl (1) Biochemical Assay Reagents (20) Carbonic Anhydrase (1) Caspase (2) CDK (2) Checkpoint Kinase (Chk) (1) Collagen (3) Cytochrome P450 (34) DNA/RNA Synthesis (6) Drug Derivative (4) Drug Intermediate (11) Drug Metabolite (7) E1/E2/E3 Enzyme (2) EGFR (1) Endogenous Metabolite (25) Environmental Pollutants (12) Epigenetic Reader Domain (1) ERK (5) Estrogen Receptor/ERR (5) FAAH (2) Ferroptosis (2) FGFR (1) Fluorescent Dye (2) Fungal (11) G protein-coupled Bile Acid Receptor 1 (1) GLP Receptor (2) GLUT (2) Glycosidase (2) GSK-3 (2) HBV (1) Herbicide (1) HIF/HIF Prolyl-Hydroxylase (1) HIV (1) Indoleamine 2,3-Dioxygenase (IDO) (2) Influenza Virus (1) Integrin (3) Interleukin Related (7) IRE1 (1) Isotope-Labeled Compounds (18) JAK (1) JNK (3) LIM Kinase (LIMK) (1) LPL Receptor (2) LXR (1) MCHR1 (GPR24) (1) MDM-2/p53 (5) MEK (2) Microtubule/Tubulin (1) Mitophagy (2) MOFs (1) Monoamine Oxidase (2) mTOR (1) Na+/K+ ATPase (1) NF-κB (5) Notch (1) p38 MAPK (7) PARP (2) PDI (1) PDK-1 (1) PERK (4) Phosphatase (1) PI3K (3) PKD (1) PPAR (3) Prostaglandin Receptor (1) PROTACs (1) Pyroptosis (2) Reactive Oxygen Species (ROS) (6) Reference Standards (35) Ser/Thr Protease (1) STAT (1) TGF-beta/Smad (1) UGT (3) Vasopressin Receptor (1) VD/VDR (2) VEGFR (1) β-glucuronidase (1)
By Research Areas:	Cancer (102) Cardiovascular Disease (12) Endocrinology (12) Infection (19) Inflammation/Immunology (54) Metabolic Disease (28) Neurological Disease (28)
Click Chemistry:	Labeling and Fluorescence Imaging (1) Azide (5) Alkynes (3)

241

Inhibitors & Agonists

Fluorescent Dye

Biochemical Assay Reagents

Peptides

Natural
Products

Recombinant Proteins

Isotope-Labeled Compounds

Antibodies

Click Chemistry

GMP Molecules

L-Kynurenine Maximum Cited Publications 25 Publications Verification	Aryl Hydrocarbon Receptor Endogenous Metabolite	Cardiovascular Disease Neurological Disease Inflammation/Immunology Cancer
L-Kynurenine is a metabolite of the amino acid L-tryptophan. L-Kynurenine is an aryl hydrocarbon receptor agonist.

Stemregenin 1 15+ Cited Publications SR1	Aryl Hydrocarbon Receptor	Cancer
Stemregenin 1 is a potent aryl hydrocarbon receptor (AhR) antagonist with IC₅₀ of 127 nM.

Tapinarof 10+ Cited Publications WBI-1001; Benvitimod; GSK2894512	Aryl Hydrocarbon Receptor	Inflammation/Immunology
Tapinarof (WBI-1001) is a natural aryl hydrocarbon receptor (AhR) agonist with an EC₅₀ of 13 nM. Tapinarof resolves skin inflammation in mice .

Pifithrin-α hydrobromide 95+ Cited Publications Pifithrin hydrobromide; PFTα hydrobromide	MDM-2/p53 Aryl Hydrocarbon Receptor Ferroptosis Apoptosis	Cancer
Pifithrin-α hydrobromide is a p53 inhibitor which blocks its transcriptional activity and prevents cells from apoptosis. Pifithrin-α hydrobromide is also an aryl hydrocarbon receptor (AhR) agonist.

Diosmin 15+ Cited Publications	Aryl Hydrocarbon Receptor	Cardiovascular Disease Cancer
Diosmin is a flavonoid found in a variety of citrus fruits and also an agonist of the aryl hydrocarbon receptor (AhR).

Tyloxapol 5 Publications Verification	Biochemical Assay Reagents	Metabolic Disease
Tyloxapol is a nonionic liquid polymer of the alkyl aryl polyether alcohol type, used as a surface active stabilizer. Tyloxapol is used to induce hyperlipidemia in animals .

FICZ 25+ Cited Publications 6-Formylindolo[3,2-b]carbazole	Aryl Hydrocarbon Receptor	Others
FICZ is a potent aryl hydrocarbon receptor (AhR) agonist with a K_d of 70 pM.

Carbidopa 2 Publications Verification (S)-(-)-Carbidopa	Aryl Hydrocarbon Receptor	Neurological Disease Cancer
Carbidopa ((S)-(-)-Carbidopa), a peripheral decarboxylase inhibitor, can be used for the research of Parkinson's disease. Carbidopa is a selective aryl hydrocarbon receptor (AhR) modulator. Carbidopa inhibits pancreatic cancer cell and tumor growth .

XPhos 2-(Dicyclohexylphosphino)-2',4',6'-triisopropylbiphenyl	Biochemical Assay Reagents	Others
XPhos is a dual aryl monophosphine ligand. XPhos is an efficient and stable palladium catalytic ligand. XPhos can be used for amination of aryl sulfonate esters .

Indole-3-carbinol 15+ Cited Publications Indole-3-methanol	NF-κB Aryl Hydrocarbon Receptor E1/E2/E3 Enzyme Endogenous Metabolite	Cancer
Indole-3-carbinol (I3C) inhibits NF-κB activity and also is an Aryl hydrocarbon receptor (AhR) agonist, and an inhibitor of WWP1 (WW domain-containing ubiquitin E3 ligase 1).

L-Kynurenine (Standard) Maximum Cited Publications 25 Publications Verification	Reference Standards Aryl Hydrocarbon Receptor Endogenous Metabolite	Cardiovascular Disease Neurological Disease Inflammation/Immunology Cancer
L-Kynurenine (Standard) is the analytical standard of L-Kynurenine. This product is intended for research and analytical applications. L-Kynurenine is a metabolite of the amino acid L-tryptophan. L-Kynurenine is an aryl hydrocarbon receptor agonist.

GNF351 5+ Cited Publications	Aryl Hydrocarbon Receptor	Others
GNF351 is a full aryl hydrocarbon receptor (AHR) antagonist. GNF351 competes with a photoaffinity AHR ligand for binding to the AHR with an IC₅₀ of 62 nM. GNF351 is minimal toxicity in mouse or human keratinocytes .

Skatole 5+ Cited Publications 3-Methylindole; 3-Methyl-1H-indole	Environmental Pollutants Apoptosis Endogenous Metabolite p38 MAPK Aryl Hydrocarbon Receptor	Others
Skatole (3-methylindole) is a heterocyclic compound naturally found in the feces of vertebrates and can be found in certain plants. Skatole can be produced by intestinal bacteria, inducing apoptosis of intestinal epithelial cells through activating aryl hydrocarbon receptors (AhR) and p38. Skatole has been used in specific products of the perfume industry or as a flavor additive in ice cream .

Prochloraz 1 Publications Verification BTS 40542	Environmental Pollutants Estrogen Receptor/ERR Aryl Hydrocarbon Receptor Fungal Androgen Receptor	Infection Endocrinology
Prochloraz is an imidazole antifungal. Prochloraz is as an estrogen receptor (ER) and androgen receptor (AR) antagonist and an aromatase inhibitor with IC₅₀ values of 25 μM, 4 μM and 0.3 μM, respectively. Prochloraz is able to activate the aryl hydrocarbon receptor (AhR) having an EC₅₀ of 1 μM .

ITE 5+ Cited Publications	Aryl Hydrocarbon Receptor	Inflammation/Immunology Cancer
ITE is a potent endogenous agonist of aryl hydrocarbon receptor (AhR), binding directly to AHR, with a K_i of 3 nM. ITE also has immunosuppressive activity.

YL-109 2 Publications Verification	Aryl Hydrocarbon Receptor	Cancer
YL-109 is an antitumor agent that can induce carboxyl terminus of Hsp70-interacting protein (CHIP) expression through aryl hydrocarbon receptor (AhR) signaling. YL-109 has ability to inhibit breast cancer cell growth and invasiveness .

BAY-218 2 Publications Verification AHR antagonist 1	Aryl Hydrocarbon Receptor	Inflammation/Immunology Cancer
BAY-218 (AHR antagonist 1) is an aryl hydrocarbon receptor (AHR) antagonist. BAY-218 has AHR inhibitory activity with an IC₅₀ of 39.9 nM in in U87 glioblastoma cells. BAY-218 can be used for the research of cancer or conditions with dysregulated immune responses .

Mono(2-ethyl-5-hydroxyhexyl) phthalate MEHHP	Drug Metabolite Apoptosis Aryl Hydrocarbon Receptor	Cancer
Mono (2-ethyl-5-hydroxyhexyl) phthalate (MEHHP) is a biomarker for human exposure to DEHP (HY-B1945). By activating the tryptophan-kynurenine-aryl hydrocarbon receptor (AhR) pathway, mono (2-ethyl-5-hydroxyhexyl) phthalate significantly increases the viability of primary uterine leiomyoma cells and reduces cell apoptosis. Mono (2-ethyl-5-hydroxyhexyl) phthalate correlates with decreased sperm DNA damage. Mono (2-ethyl-5-hydroxyhexyl) phthalate can be used in studies related to uterine leiomyoma .

Carbidopa monohydrate 2 Publications Verification (S)-(-)-Carbidopa monohydrate	Aryl Hydrocarbon Receptor	Neurological Disease Cancer
Carbidopa ((S)-(-)-Carbidopa) monohydrate, a peripheral decarboxylase inhibitor, can be used for the research of Parkinson's disease. Carbidopa monohydrate is a selective aryl hydrocarbon receptor (AhR) modulator. Carbidopa monohydrate inhibits pancreatic cancer cell and tumor growth .

Norisoboldine (+)-Laurelliptine	Adenosine Receptor	Inflammation/Immunology
Norisoboldine is an orally active natural aryl hydrocarbon receptor (AhR) agonist. Norisoboldine, as a major isoquinoline alkaloid present in Radix Linderae, can be used for the research of Rheumatoid arthritis and Ulcerative colitis .

MeBIO	Aryl Hydrocarbon Receptor GSK-3 CDK	Others
MeBIO is a potent AhR (aryl hydrocarbon receptor) agonist, with IC₅₀ of 44 μM (GSK-3) and 55 μM (CDK1/cyclin B), respectively .

PDM2 3 Publications Verification	Aryl Hydrocarbon Receptor	Inflammation/Immunology
PDM2 is a selective, high-affinity aryl hydrocarbon receptor (AhR) antagonist with an K_i of 1.2±0.4 nM.

MKC9989 1 Publications Verification	IRE1	Cancer
MKC9989 is a *Hydroxy aryl* aldehydes (HAA) inhibitor and also inhibits IRE1α with an IC₅₀** of 0.23 to 44 μM.

Diosmin (Standard)	Reference Standards Aryl Hydrocarbon Receptor	Cardiovascular Disease Cancer
Diosmin (Standard) is the analytical standard of Diosmin. This product is intended for research and analytical applications. Diosmin is a flavonoid found in a variety of citrus fruits and also an agonist of the aryl hydrocarbon receptor (AhR).

N-Boc-O-tosyl hydroxylamine	Amino Acid Derivatives	Others
N-Boc-O-tosyl hydroxylamine is a safe and efficient nitrogen source for N-amination of aryl and alkyl amines. N-Boc-O-tosyl hydroxylamine promotes electrophilic N-amination of aryl amines and alkyl amines to generate β-Boc-protected aryl hydrazines and alkyl hydrazines .

1,4-Chrysenequinone Chrysene-1,4-dione	Aryl Hydrocarbon Receptor	Cancer
1,4-Chrysenequinone, a polycyclic aromatic quinone, acts as an activator of aryl hydrocarbon receptor (AhR).

6,2',4'-Trimethoxyflavone 1 Publications Verification	Aryl Hydrocarbon Receptor	Neurological Disease Cancer
6,2',4'-Trimethoxyflavone is a potent aryl hydrocarbon receptor (AHR) antagonist. 6,2',4'-Trimethoxyflavone represses AHR-mediated gene induction .

Norisoboldine hydrochloride (+)-Laurelliptine hydrochloride	Adenosine Receptor	Inflammation/Immunology
Norisoboldine hydrochloride is an orally active natural aryl hydrocarbon receptor (AhR) agonist. Norisoboldine hydrochloride, as a major isoquinoline alkaloid present in Radix Linderae, can be used for the research of Rheumatoid arthritis and Ulcerative colitis .

DiMNF 3',4'-Dimethoxy-αNF	Aryl Hydrocarbon Receptor	Inflammation/Immunology
DiMNF (3',4'-Dimethoxy-αNF) is a selective aryl hydrocarbon receptor (AHR) modulator. DiMNF is a competitive AHR ligand (IC₅₀ = 21 nM) with apparent antagonistic activity. DiMNF can be used as an anti-inflammatory agent .

DEPMPO	Biochemical Assay Reagents	Cancer
cDEPMPO is a potent anticancer proagent. High concentrations of DEPMPO spin-trap the ·OH radical together with aryl radicals arising from one-electron reduced BTO (benzotriazine 1,4-di-N-oxide) compounds .

Skatole (Standard) 3-Methylindole (Standard); 3-Methyl-1H-indole (Standard)	Reference Standards Aryl Hydrocarbon Receptor p38 MAPK Endogenous Metabolite Apoptosis	Others
Skatole (Standard) is the analytical standard of Skatole. This product is intended for research and analytical applications. Skatole (3-methylindole) is a heterocyclic compound naturally found in the feces of vertebrates and can be found in certain plants. Skatole can be produced by intestinal bacteria, inducing apoptosis of intestinal epithelial cells through activating aryl hydrocarbon receptors (AhR) and p38. Skatole has been used in specific products of the perfume industry or as a flavor additive in ice cream .

BFMO N,N'-Difurfuryloxamide; N1,N2-Bis(furan-2-ylmethyl)oxalamide	Biochemical Assay Reagents	Others
BFMO (N,N'-Difurfuryloxamide) is an oxamide derivative and a bidentate ligand. BFMO exhibits plant growth regulatory activity and root growth inhibitory activity. BFMO can promote the copper-catalyzed N-arylation reaction between aniline compounds and cyclic secondary amines, realizing the coupling of (hetero) aryl bromides with (hetero) aryl amines and cyclic secondary amines .

CAY10464 AHR antagonist 7	Aryl Hydrocarbon Receptor	Cancer
CAY10464 (AHR antagonist 7; compound 4j) is a selective and high-affinity aryl hydrocarbon receptor (AhR) antagonist with a K_i of 1.4 nM .

Dimethyl Citric acid 1 Publications Verification	Others	Others
Dimethylurea/citric acid is a highly efficient deep eutectic solvent (DES). Dimethylurea/citric acid can be used as a catalyst and a green reaction medium for the synthesis of bis(indolyl)methanes, quinolines and aryl-4, 5-diphenyl-1H-imidazoles.

Glucoerucin potassium	Aryl Hydrocarbon Receptor	Others
Glucoerucin potassium is an aryl hydrocarbon receptor antagonist and is the 4-methylthio-butyl glucosinolate found in the seeds of Eruca sativa Mill .

Glucoerucin	Endogenous Metabolite Aryl Hydrocarbon Receptor	Others
Glucoerucin is an aryl hydrocarbon receptor antagonist and is the 4-methylthio-butyl glucosinolate found in the seeds of Eruca sativa Mill .

α-Peltatin	Fungal	Others
α-Peltatin is an aryl lignan. α-Peltatin has anticancer and antifungal activity. α-Peltatin inhibits DNA topoisomerase and tubulin polymerization .

STAT3-IN-7	STAT	Cancer
STAT3-IN-7, an aryl sulfonamido azetidine compound, is an orally active STAT3 inhibitor. STAT3-IN-7 has anticancer activities (WO2021016333A1, H182) .

L-Kynurenine sulfate	Endogenous Metabolite Aryl Hydrocarbon Receptor	Inflammation/Immunology
L-Kynurenine sulfate, an aryl hydrocarbon receptor (AHR) agonist that activates AHR-directed, naive T cell polarization to the anti-inflammatory Treg phenotype .

Benz[a]anthracene Tetraphene	Environmental Pollutants Aryl Hydrocarbon Receptor	Others
Benz[a]anthracene (Tetraphene) (Compound 92) is a ligand for the aryl hydrocarbon receptor (AhR) with a pIC₅₀ of 7.319. Benz[a]anthracene is a polycyclic aromatic hydrocarbon (PAH) that can be detected in spruce needles near aluminum smelters .

Cat. No.	Product Name	Type

HY-D0932

Sudan IV

Solvent Red 24; C.I. 26105

Fluorescent Dye

Sudan IV is an agonist of the aryl hydrocarbon receptor (AhR) that activates downstream signaling pathways and induces CYP1A1 expression. Sudan IV promotes CYP1A1 gene transcription by activating AhR-ARNT heterodimers and binding to exogenous response elements (XREs) on DNA, thereby enhancing drug metabolizing enzyme activity. Sudan IV can be used to study the toxicity mechanisms of industrial dyes and the effects of interactions with serum proteins (such as bovine serum albumin (BSA)) on their distribution in vivo. Sudan IV is a fat-soluble diazo dye that can be used to stain lipids, triglycerides, and lipoproteins on frozen sections .

HY-15001G

Stemregenin 1

SR1

Fluorescent Dye

Stemregenin 1 (SR1) (GMP) is a GMP-grade Stemregenin 1 (HY-15001). GMP-grade small molecules can be used as adjuvants in cell therapy. Stemregenin 1 is a potent aryl hydrocarbon receptor (AhR) antagonist with an IC₅₀ of 127 nM. Stemregenin 1 (GMP) can competitively bind to AhR and inhibit its nuclear translocation, inhibiting osteoclastogenesis and promoting hematopoietic progenitor cell expansion by blocking the AhR-c-src-NF-κB/p-ERK MAPK-NFATc1 signaling pathway. Stemregenin 1 (GMP) can be used for the study of osteoporosis, in vitro expansion of hematopoietic stem cells, and the study of the mechanism of bone metabolic diseases .

HY-151662

4-Azido-2,3,5,6-tetrafluorobenzoic Acid

N3-TFBA

Fluorescent Dye

4-Azido-2,3,5,6-tetrafluorobenzoic Acid (N3-TFBA) is a click chemistry reagent containing an azide group. 4-Azido-2,3,5,6-tetrafluorobenzoic Acid is a complex with FAM-labeled DNA probe. 4-Azido-2,3,5,6-tetrafluorobenzoic Acid can be used as versatile photoaffinity labeling agents to probe biological receptors. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

HY-D1213

4-Nitrocatechol sulfate dipotassium salt Dipotassium nitrocatechol sulfate	Fluorescent Dye
4-Nitrocatechol sulfate potassium salt (Dipotassium nitrocatechol sulfate) is an aromatic sulfate that can serve as a chromogenic substrate for sulfatase. 4-Nitrocatechol sulfate potassium salt can be used to determine the activities of glycosaminoglycan (GAG) degrading enzymes aryl sulfatase B and exonucleosidase .

HY-D0932R

Sudan IV (Standard)

Solvent Red 24 (Standard); C.I. 26105 (Standard)

Fluorescent Dye

Sudan IV (Standard) (Solvent Red 24 (Standard)) is the analytical standard of Sudan IV (HY-D0932). This product is intended for research and analytical applications. Sudan IV is an agonist of the aryl hydrocarbon receptor (AhR) that activates downstream signaling pathways and induces CYP1A1 expression. Sudan IV promotes CYP1A1 gene transcription by activating AhR-ARNT heterodimers and binding to exogenous response elements (XREs) on DNA, thereby enhancing drug metabolizing enzyme activity. Sudan IV can be used to study the toxicity mechanisms of industrial dyes and the effects of interactions with serum proteins (such as bovine serum albumin (BSA)) on their distribution in vivo. Sudan IV is a fat-soluble diazo dye that can be used to stain lipids, triglycerides, and lipoproteins on frozen sections.

Cat. No.	Product Name	Type

HY-Y0006

XPhos 2-(Dicyclohexylphosphino)-2',4',6'-triisopropylbiphenyl	Biochemical Assay Reagents
XPhos is a dual aryl monophosphine ligand. XPhos is an efficient and stable palladium catalytic ligand. XPhos can be used for amination of aryl sulfonate esters .

HY-15001G

Stemregenin 1

SR1

Biochemical Assay Reagents

HY-W014018

2,5-Diphenyloxazole PPO; DPO; POP	Biochemical Assay Reagents
2,5-Diphenyloxazole (PPO; DPO; POP) is a fluorescent dye, as well as a substrate and metabolite precursor of cytochrome P-450 (cytochrome P-448/P₁-450). 2,5-Diphenyloxazole serves as a scintillator .

HY-W002849

Cyjohnphos 2-(Dicyclohexylphosphino)biphenyl	Biochemical Assay Reagents
Cyjohnphos is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Cyjohnphos can be used in combination with a nickel catalyst for the Suzuki-Miyaura arylation of tertiary benzylic acetates with aryl boroxines to produce diaryl and triaryl quaternary stereocenters .

HY-W054259

BFMO N,N'-Difurfuryloxamide; N1,N2-Bis(furan-2-ylmethyl)oxalamide	Biochemical Assay Reagents
BFMO (N,N'-Difurfuryloxamide) is an oxamide derivative and a bidentate ligand. BFMO exhibits plant growth regulatory activity and root growth inhibitory activity. BFMO can promote the copper-catalyzed N-arylation reaction between aniline compounds and cyclic secondary amines, realizing the coupling of (hetero) aryl bromides with (hetero) aryl amines and cyclic secondary amines .

HY-W002805

2-Bromoisonicotinic acid 1 Publications Verification	Biochemical Assay Reagents
2-Bromoisonicotinic acid is a (hetero)aryl bromide building block and DNA-conjugated headpiece for photochemical C-H heteroarylation in DNA-encoded library synthesis. 2-Bromoisonicotinic acid generates a nucleophilic pyridyl radical intermediate. 2-Bromoisonicotinic acid, when conjugated to DNA, leaves electrophilic handles intact for subsequent library diversification .

HY-42045

Pyrimidine-5-boronic acid pinacol ester

Biochemical Assay Reagents

Pyrimidine-5-boronic acid pinacol ester is a derivative of Boronic acid. Boronic acid is an intermediate commonly used in organic synthesis reactions and can be used as a key reagent in the Suzuki-Miyaura reaction. It generates organic free radicals through oxygen-mediated oxidation and exhibits potential mutagenic activity. Boronic acid is mainly used in research in the fields of drug synthesis and catalytic reactions. Pyrimidine-5-boronic acid pinacol ester serves as a building block in DNA-compatible one-pot click chemistry for synthesis of DNA-encoded libraries .

HY-34619

[Hydroxy(tosyloxy)iodo]benzene 1 Publications Verification	Biochemical Assay Reagents
[Hydroxy(tosyloxy)iodo]benzene is a versatile reagent for the mild oxidation of aryl iodides at the iodine atom by ligand transfer. [Hydroxy(tosyloxy)iodo]benzene is an effective reagent for the one-step conversion of ketones to the corresponding α-tosyloxy ketones. [Hydroxy(tosyloxy)iodo]benzene is also a Bronsted acid and is expected to catalyze the enolization of ketones .

HY-W097697

Trifluoro(3-methoxyphenyl)borate Potassium	Biochemical Assay Reagents
Trifluoro(3-methoxyphenyl)borate Potassium is an aryl trifluoroborate compound.

HY-W011086R

Tri-O-tolyl phosphate (Standard)

Tri-O-cresyl phosphate (Standard); TOTP (Standard)

Biochemical Assay Reagents

Tri-O-tolyl phosphate (Tri-O-cresyl phosphate; TOTP) (Standard) is an analytical standard of Tri-O-tolyl phosphate (HY-W011086). This product is intended for research and analytical applications. Tri-O-tolyl phosphate is an aryl phosphate compounds commonly utilized as flame retardants and lubricant additives across various industrie. Tri-O-tolyl phosphate has neurotoxicity and reproductive toxicity, decreasing cell viability, inhibiting cell proliferation, triggering cell cycle arrest, induceing apoptosis, causing mitochondrial dysfunction, disrupts calcium homeostasis .

Cat. No.	Product Name	Target	Research Area

HY-P4582

Suc-Phe-Ala-Ala-Phe-pNA Suc-FAAF-pNA	Ser/Thr Protease	Others
Suc-Phe-Ala-Ala-Phe-pNA (Suc-FAAF-pNA) is a chromogenic polypeptide substrate that can be used for the quantitative activity assay of intracellular subtilisin (ISP) and neutral metalloprotease (NPS) derived from Saccharomonospora canescens. Suc-Phe-Ala-Ala-Phe-pNA is hydrolyzed by the catalytic triad of mature proteases to release the chromophore pNA. Suc-Phe-Ala-Ala-Phe-pNA is applicable to enzymological studies .

HY-W104304

2-(3-Trifluoromethylphenyl)glycine hydrochloride	Vasopressin Receptor	Cardiovascular Disease
2-(3-Trifluoromethylphenyl)glycine hydrochloride is a precursor of substituted 2-acetamido-5-aryl-l, 2,4-triazolones. Substituted 2-acetamido-5-aryl-l, 2,4-triazolones are dual V1a/V2 receptor antagonists and can be used in cardiovascular disease research .

Species:	Human (7)
Tag:	His (6) Strep (1) Tag Free (1)
Source:	Sf9 insect cells (2) E. coli (5)

Cat. No.	Compare	Product Name	Species	Source	Image

HY-P704187

	AHR Protein, Human (His) aryl hydrocarbon receptor; Ah receptor; lass E basic helix-loop-helix protein 76 (bHLHe76); AHR; BHLHE76	Human	E. coli
	AHR Protein, Human (His) is the recombinant human-derived AHR protein, expressed by E. coli, with N-10*His tag.

HY-P701572

	IVNS1ABP Protein, Human (sf9) IVNS1ABP; Influenza virus NS1A-binding protein; NS1-BP; NS1-binding protein; aryl hydrocarbon receptor-associated protein 3; Kelch-like protein 39	Human	Sf9 insect cells
	The IVNS1ABP protein is intricately involved in multiple cellular functions, including pre-mRNA splicing, aryl hydrocarbon receptor (AHR) pathway, F-actin organization, and protein ubiquitination. It binds to F-actin through Kelch repeats, thereby stabilizing actin filaments and thereby protecting cells from actin instability-induced cell death. IVNS1ABP Protein, Human (sf9) is the recombinant human-derived IVNS1ABP protein, expressed by sf9 insect cells , with tag free.

HY-P701573

	IVNS1ABP Protein, Human (sf9, His, StrepⅡ) IVNS1ABP; Influenza virus NS1A-binding protein; NS1-BP; NS1-binding protein; aryl hydrocarbon receptor-associated protein 3; Kelch-like protein 39	Human	Sf9 insect cells
	The IVNS1ABP protein is intricately involved in multiple cellular functions, including pre-mRNA splicing, aryl hydrocarbon receptor (AHR) pathway, F-actin organization, and protein ubiquitination. It binds to F-actin through Kelch repeats, thereby stabilizing actin filaments and thereby protecting cells from actin instability-induced cell death. IVNS1ABP Protein, Human (sf9, His, Strep) is the recombinant human-derived IVNS1ABP protein, expressed by sf9 insect cells , with N-Strep, N-8*His labeled tag.

HY-P71001

	SULT1A2 Protein, Human (His) Sulfotransferase 1A2; ST1A2; aryl Sulfotransferase 2; Phenol Sulfotransferase 2; Phenol-Sulfating Phenol Sulfotransferase 2; P-PST 2; SULT1A2; STP2	Human	E. coli
	Sulfotransferase 1A2 (SULT1A2) is a phenol sulfotransferase with thermostable enzyme activity. SULT1A2 utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of catecholamines, phenolic drugs and neurotransmitters. SULT1A2 is also responsible for the sulfonation and activation of minoxidil. SULT1A2 induces the mutagenicity and carcinogenicity of certain substrates by influencing DNA adduct formation. SULT1A2 Protein, Human (His) is the recombinant human-derived SULT1A2 protein, expressed by E. coli , with N-6*His labeled tag.

HY-P71341

	SULT1A3 Protein, Human (His, solution) Sulfotransferase 1A3/1A4; ST1A3/ST1A4; aryl Sulfotransferase 1A3/1A4; Catecholamine-Sulfating Phenol Sulfotransferase; HAST3; M-PST; Monoamine-Sulfating Phenol Sulfotransferase; Placental Estrogen Sulfotransferase; Sulfotransferase Monoamine-Preferring; Thermolabi	Human	E. coli
	SULT1A3 protein, a sulfotransferase utilizing PAPS, catalyzes the sulfate conjugation of phenolic monoamines, including neurotransmitters (dopamine, norepinephrine, serotonin) and drugs. This activity contributes significantly to inactivation and elimination, emphasizing SULT1A3's crucial role in regulating neurotransmitter and drug levels, maintaining homeostasis, and ensuring proper biological system functioning. SULT1A3 Protein, Human (His, solution) is the recombinant human-derived SULT1A3 protein, expressed by E. coli , with N-6*His labeled tag.

HY-P71341A

	SULT1A3 Protein, Human (N-His) Sulfotransferase 1A3/1A4; ST1A3/ST1A4; aryl Sulfotransferase 1A3/1A4; Catecholamine-Sulfating Phenol Sulfotransferase; HAST3; M-PST; Monoamine-Sulfating Phenol Sulfotransferase; Placental Estrogen Sulfotransferase; Sulfotransferase Monoamine-Preferring; Thermolabi	Human	E. coli
	SULT1A3 protein, a sulfotransferase utilizing PAPS, catalyzes the sulfate conjugation of phenolic monoamines, including neurotransmitters (dopamine, norepinephrine, serotonin) and drugs. This activity contributes significantly to inactivation and elimination, emphasizing SULT1A3's crucial role in regulating neurotransmitter and drug levels, maintaining homeostasis, and ensuring proper biological system functioning. SULT1A3 Protein, Human (N-His) is the recombinant human-derived SULT1A3, expressed by E. coli, with N-6*His labeled tag.

HY-P70969

	SULT1A1 Protein, Human (His) Sulfotransferase 1A1; ST1A1; aryl sulfotransferase 1; HAST1/HAST2; Phenol Sulfotransferase 1; Phenol-Sulfating Phenol Sulfotransferase 1; P-PST 1; ST1A3; Thermostable Phenol Sulfotransferase; Ts-PST; SULT1A1; STP; STP1; OK/SW-cl.88	Human	E. coli
	SULT1A1 Protein, Human (His) is the recombinant human-derived SULT1A1 protein, expressed by E. coli, with N-6*His labeled tag.

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Cat. No.	Product Name	Chemical Structure

HY-104026S

L-Kynurenine-d4 1 Publications Verification
L-Kynurenine-d₄ is the deuterium labeled L-Kynurenine. L-Kynurenine is a metabolite of the amino acid L-tryptophan. L-Kynurenine is an aryl hydrocarbon receptor agonist[1][2].

HY-W011338S

Benzyl butyl phthalate-d4

Benzyl butyl phthalate-d₄ is the deuterium labeled Benzyl butyl phthalate . Benzyl butyl phthalate, a member of phthalic acid esters (PAEs), can trigger the migration and invasion of hemangioma (HA) cells via upregulation of Zeb1. Benzyl butyl phthalate activates aryl hydrocarbon receptor (AhR) in breast cancer cells to stimulate SPHK1/S1P/S1PR3 signaling and enhances formation of metastasis-initiating breast cancer stem cells (BCSCs) .

HY-132429S

Potassium 1H-indol-3-yl sulfate-d5

Potassium 1H-indol-3-yl sulfate-d₅ is the deuterium labeled 3-Indoxyl Sulfate potassium. Potassium 1H-indol-3-yl sulfate is a metabolite of tryptophan, produced by intestinal microorganisms and combined with sulfate in the liver before entering the circulatory system. Potassium 1H-indol-3-yl sulfate is a potent endogenous agonist of the aryl hydrocarbon receptor (AhR) and a urinary toxin. Potassium 1H-indol-3-yl sulfate can be used for research on kidney diseases.

HY-W007355S

Skatole-d3
Skatole-d₃ is the deuterium labeled Skatole. Skatole is produced by intestinal bacteria, regulates intestinal epithelial cellular functions through activating aryl hydrocarbon receptors and p38 .

HY-W014075S

1-Hydroxypyrene-d9
1-Hydroxypyrene-d₉ is the deuterium labeled 1-Hydroxypyrene (HY-W014075). 1-Hydroxypyrene, a biomarker of exposure to polycyclic aromatic hydrocarbons (PAHs), is analyzed in urine samples. 1-Hydroxypyrene is the major biomarker of exposure to pyrenes. 1-Hydroxypyrene is the orally active agonist for aryl hydrocarbon receptor (AhR) and can lead to renal fibrosis .

HY-W011910S

Potassium 1H-indol-3-yl sulfate-d4

Potassium 1H-indol-3-yl sulfate-d₄ potassium is the deuterium labeled Potassium 1H-indol-3-yl sulfate. Potassium 1H-indol-3-yl sulfate is a metabolite of tryptophan, produced by intestinal microorganisms and combined with sulfate in the liver before entering the circulatory system. Potassium 1H-indol-3-yl sulfate is a potent endogenous agonist of the aryl hydrocarbon receptor (AhR) and a urinary toxin. Potassium 1H-indol-3-yl sulfate can be used for research on kidney diseases.

HY-104026S5

L-Kynurenine-13C10 sulfate hydrate
L-Kynurenine-13C10 sulfate hydrate is the C13 labeled L-Kynurenine sulfate hydrate. L-Kynurenine is an aryl hydrocarbon receptor agonist .

HY-104026S1

L-Kynurenine-d4-1
L-Kynurenine-d₄-1 is deuterium labeled L-Kynurenine. L-Kynurenine is a metabolite of the amino acid L-tryptophan. L-Kynurenine is an aryl hydrocarbon receptor agonist.

HY-W007355S1

Skatole-d8
Skatole-d₈ is the deuterium labeled Skatole. Skatole is produced by intestinal bacteria, regulates intestinal epithelial cellular functions through activating aryl hydrocarbon receptors and p38 .

HY-104026S2

L-Kynurenine-d4-1 hydrochloride
L-Kynurenine-d₄-1 hydrochloride is the deuterium labeled L-Kynurenine (HY-104026). L-Kynurenine is a metabolite of the amino acid L-tryptophan. L-Kynurenine is an aryl hydrocarbon receptor agonist .

HY-B0311AS

Carbidopa-d3 monohydrate
Carbidopa-d₃ (monohydrate) is the deuterium labeled Carbidopa monohydrate. Carbidopa ((S)-(-)-Carbidopa) monohydrate, a peripheral decarboxylase inhibitor, can be used for the research of Parkinson's disease. Carbidopa monohydrate is a selective aryl hydrocarbon receptor (AhR) modulator. Carbidopa monohydrate inhibits pancreatic cancer cell and tumor growth .

HY-Y1322S

Triphenyl phosphate-d15

Triphenyl phosphate-d₁₅ is the deuterium labeled Triphenyl phosphate. Triphenyl phosphate is an orally active, blood-brain barrier-permeable aryl organophosphate flame retardant and endocrine disruptor. Triphenyl phosphate disrupts mitochondrial dynamic balance through oxidative stress, induces excessive mitophagy and apoptosis, and ultimately leads to myocardial fibrosis. In the brain, Triphenyl phosphate activates the NF-κB inflammatory pathway by disrupting the gut microbiota, alters tryptophan metabolism and elevates neurotoxins, thereby inducing anxiety- and depression-like behaviors. In the skeletal and reproductive systems, Triphenyl phosphate inhibits osteoblast differentiation and induces germ cell apoptosis by suppressing the MAPK/ERK pathway and activating the JNK signal, respectively. In adipose and placental tissues, Triphenyl phosphate promotes lipid accumulation by activating the PI3K/AKT-PPARγ axis, and disrupts placental metabolism via the MAOA/ROS/NF-κB cascade, impairing neurodevelopment of offspring.

HY-104026CS

L-Kynurenine-13C10 sulfate hemihydrate
L-Kynurenine- ¹³C10 (sulfate hemihydrate) is the ¹³C labeled L-Kynurenine sulfate. L-Kynurenine sulfate hemihydrate, an aryl hydrocarbon receptor (AHR) agonist that activates AHR-directed, naive T cell polarization to the anti-inflammatory Treg phenotype .

HY-104026BS

L-Kynurenine-13C10 sulfate
L-Kynurenine-13C10 (sulfate) is the 13C labeled L-Kynurenine sulfate. L-Kynurenine sulfate, an aryl hydrocarbon receptor (AHR) agonist that activates AHR-directed, naive T cell polarization to the anti-inflammatory Treg phenotype .

HY-104026S3

L-Kynurenine-13C4,15N-1
L-Kynurenine- ¹³C₄, ¹⁵N-1 is the ¹³C and ¹⁵N labled L-Kynurenine (HY-104026) . L-Kynurenine is a metabolite of the amino acid L-tryptophan. L-Kynurenine is an aryl hydrocarbon receptor agonist.

HY-133677S

Mono(2-ethyl-5-hydroxyhexyl) phthalate-d4

Mono(2-ethyl-5-hydroxyhexyl) phthalate-d₄ (MEHHP-d₄) is a deuterium labeled Mono(2-ethyl-5-hydroxyhexyl) phthalate (HY-133677). Mono (2-ethyl-5-hydroxyhexyl) phthalate is a biomarker for human exposure to DEHP (HY-B1945). By activating the tryptophan-kynurenine-aryl hydrocarbon receptor (AhR) pathway, mono (2-ethyl-5-hydroxyhexyl) phthalate significantly increases the viability of primary uterine leiomyoma cells and reduces cell apoptosis. Mono (2-ethyl-5-hydroxyhexyl) phthalate correlates with decreased sperm DNA damage. Mono (2-ethyl-5-hydroxyhexyl) phthalate can be used in studies related to uterine leiomyoma.

HY-W754764S

11-(4-Nitrosopiperazin-1-yl)dibenzo[b,f][1,4]thiazepine-d8
11-(4-Nitrosopiperazin-1-yl)dibenzo[b,f][1,4]thiazepine-d₈ (Nitroso aryl piperazine-d₈) is deuterium labeled Nitroso aryl piperazine .

HY-109044S

Tapinarof-d5
Tapinarof-d₅ (WBI-1001-d₅) is deuterium labeled Tapinarof. Tapinarof (WBI-1001) is a natural aryl hydrocarbon receptor (AhR) agonist with an EC₅₀ of 13 nM. Tapinarof resolves skin inflammation in mice .

HY-B0311S1

Carbidopa-d3-1
Carbidopa-d3-1 is the deuterium labeled Carbidopa (HY-B0311). Carbidopa, a peripheral decarboxylase inhibitor, can be used for the research of Parkinson's disease. Carbidopa is a selective aryl hydrocarbon receptor (AhR) modulator. Carbidopa inhibits pancreatic cancer cell and tumor growth .

HY-116214S

Cyprodinil-d5

Cyprodinil-d₅(CGA-219417-d₅) is the deuterium labeled Cyprodinil (HY-116214). Cyprodinil (CGA-219417) is a broad-spectrum anilinopyrimidine fungicide and an activator of the aryl hydrocarbon receptor. Cyprodinil also has anti-androgenic and androgenic activities. Cyprodinil can inhibit the biosynthesis of methionine in plant-pathogenic fungi and protect fruits and vegetables from a variety of pathogens .

HY-W716464

Prochloraz-d7
Prochloraz-d₇ (BTS 40542-d₇) is the deuterium labeled Prochloraz (HY-B0845). Prochloraz is an imidazole antifungal. Prochloraz is as an estrogen receptor (ER) and androgen receptor (AR) antagonist and an aromatase inhibitor with IC₅₀ values of 25 μM, 4 μM and 0.3 μM, respectively. Prochloraz is able to activate the aryl hydrocarbon receptor (AhR) having an EC₅₀ of 1 μM .

HY-116214S1

Cyprodinil-13C6

Cyprodinil- ¹³C₆ (CGA-219417- ¹³C₆) is the ¹³C₆ labeled Cyprodinil (HY-116214). Cyprodinil (CGA-219417) is a broad-spectrum anilinopyrimidine fungicide and an activator of the aryl hydrocarbon receptor. Cyprodinil also has anti-androgenic and androgenic activities. Cyprodinil can inhibit the biosynthesis of methionine in plant-pathogenic fungi and protect fruits and vegetables from a variety of pathogens .

HY-D0932S

Sudan IV-d6

Sudan IV-d₆ (Solvent Red 24-d₆) is the deuterium labeled Sudan IV(HY-D0932). Sudan IV is an agonist of the aryl hydrocarbon receptor (AhR) that activates downstream signaling pathways and induces CYP1A1 expression. Sudan IV promotes CYP1A1 gene transcription by activating AhR-ARNT heterodimers and binding to exogenous response elements (XREs) on DNA, thereby enhancing drug metabolizing enzyme activity. Sudan IV can be used to study the toxicity mechanisms of industrial dyes and the effects of interactions with serum proteins (such as bovine serum albumin (BSA)) on their distribution in vivo. Sudan IV is a fat-soluble diazo dye that can be used to stain lipids, triglycerides, and lipoproteins on frozen sections .

HY-G0007S

Omeprazole sulfone-d3

Omeprazole sulfone-d₃ is the deuterium labeled Omeprazole sulfone. Omeprazole sulfone (Omeprazole sulphone) is one of the major circulating metabolites of Omeprazole (HY-B0113) in vivo, and belongs to class 4 non-mutagenic impurities. Omeprazole sulfone does not bind to the aryl hydrocarbon receptor (AhR), nor does it induce the expression of CYP1A1 or CYP1A2. However, Omeprazole sulfone promotes the migration of gastric epithelial cells under basal conditions and reverses the inhibitory effect of Indomethacin (HY-14397) on cell migration. Omeprazole sulfone does not promote cell proliferation, nor does it upregulate COX-2 expression or activate signaling pathways such as ERK, P38 MAPK and PI3K. Omeprazole sulfone maintains basal ulcer healing under non-acid-dependent conditions and can be used in studies related to gastric ulcer repair .

HY-G0007S1

Omeprazole sulfone-13C,d3

Omeprazole sulfone- ¹³C,d₃ is the deuterium and ¹³C labeled Omeprazole sulfone. Omeprazole sulfone (Omeprazole sulphone) is one of the major circulating metabolites of Omeprazole (HY-B0113) in vivo, and belongs to class 4 non-mutagenic impurities. Omeprazole sulfone does not bind to the aryl hydrocarbon receptor (AhR), nor does it induce the expression of CYP1A1 or CYP1A2. However, Omeprazole sulfone promotes the migration of gastric epithelial cells under basal conditions and reverses the inhibitory effect of Indomethacin (HY-14397) on cell migration. Omeprazole sulfone does not promote cell proliferation, nor does it upregulate COX-2 expression or activate signaling pathways such as ERK, P38 MAPK and PI3K. Omeprazole sulfone maintains basal ulcer healing under non-acid-dependent conditions and can be used in studies related to gastric ulcer repair .

HY-W007355S2

Skatole-13C6

Skatole- ¹³C₆ is the ¹³C-labeled Skatole (HY-W007355). Skatole (3-methylindole) is a heterocyclic compound naturally found in the feces of vertebrates and can be found in certain plants. Skatole can be produced by intestinal bacteria, inducing apoptosis of intestinal epithelial cells through activating aryl hydrocarbon receptors (AhR) and p38. Skatole has been used in specific products of the perfume industry or as a flavor additive in ice cream.

Host:	Mouse (2) Rabbit (8)
Reactivity:	Human (10) Rat (5) Mouse (5) Hamster (2)
Application:	IHC-P (5) ICC/IF (5) IP (1) WB (10) FC (1) ELISA (2)
Isotype:	IgG (7) IgG/Kappa (1)
Conjugation:	Non-conjugated (10)
Clonality:	Monoclonal (8) Recombinant (5)
Modification:	Unmodified (8)

Cat. No.	Compare	Product Name	Application	Reactivity	Image

HY-P80378

	Aryl Hydrocarbon Receptor Antibody (YA610) 1 Publications Verification Ah receptor; Aromatic hydrocarbon receptor; aryl hydrocarbon receptor; aryl hydrocarbon receptor precursor; BHLHE76; Class E basic helix loop helix protein 76; HGNC:348; AHR_HUMAN.	WB, ICC/IF	Human
	Aryl Hydrocarbon Receptor Antibody (YA610) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Aryl Hydrocarbon Receptor.

HY-P87356

	AIP Antibody (YA7039) AH receptor interacting protein antibody; AH receptor-interacting protein antibody; AIP antibody; AIP_HUMAN antibody; ARA 9 antibody; ARA9 antibody; aryl hydrocarbon receptor interacting protein antibody; aryl-hydrocarbon receptor-interacting protein antibody; fa03h10 antibody; FKBP 16 antibody	WB	Human, Mouse, Rat
	AIP Antibody (YA7039) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to AIP.

HY-P82417

	Aryl Hydrocarbon Receptor Antibody (YA2162) Ah receptor; AhR; Class E basic helix-loop-helix protein 76; bHLHe76; AHR	WB	Human
	Aryl Hydrocarbon Receptor Antibody (YA2162) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Aryl Hydrocarbon Receptor.

HY-P82417A

	Aryl Hydrocarbon Receptor Antibody (YA2162)(PBS only) Ah receptor; AhR; Class E basic helix-loop-helix protein 76; bHLHe76; AHR	WB	Human
	Aryl Hydrocarbon Receptor Antibody (YA2162) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Aryl Hydrocarbon Receptor.

HY-P80705

	HIF1 beta Antibody (YA385) ARNT; BHLHE2; aryl hydrocarbon receptor nuclear translocator; ARNT protein; Class E basic helix-loop-helix protein 2; bHLHe2; Dioxin receptor; nuclear translocator; Hypoxia-inducible factor 1-beta; HIF-1-beta; HIF1-beta	WB, IHC-P	Human, Mouse, Rat, Hamster
	HIF1 beta Antibody (YA385) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to HIF1 beta.

HY-P85750

	HIF1 beta Antibody (YA5442) ARNT; BHLHE2; aryl hydrocarbon receptor nuclear translocator; ARNT protein; Class E basic helix-loop-helix protein 2; bHLHe2; Dioxin receptor, nuclear translocator; Hypoxia-inducible factor 1-beta; HIF-1-beta; HIF1-beta	WB, IHC-P, ICC/IF	Human, Mouse, Rat
	HIF1 beta Antibody (YA5442) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to HIF1 beta.

HY-P80705A

	HIF1 beta Antibody (YA385)(PBS only) ARNT; BHLHE2; aryl hydrocarbon receptor nuclear translocator; ARNT protein; Class E basic helix-loop-helix protein 2; bHLHe2; Dioxin receptor; nuclear translocator; Hypoxia-inducible factor 1-beta; HIF-1-beta; HIF1-beta	WB, IHC-P	Human, Mouse, Rat, Hamster
	HIF1 beta Antibody (YA385) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to HIF1 beta.

HY-P85059

	BMAL1 Antibody (YA4751) ARNTL; BHLHE5; BMAL1; MOP3; PASD3; aryl hydrocarbon receptor nuclear translocator-like protein 1; Basic-helix-loop-helix-PAS protein MOP3; Brain and muscle ARNT-like 1; Class E basic helix-loop-helix protein 5; bHLHe5; Member of PAS protein	WB, IHC-P, ICC/IF, ELISA	Human
	BMAL1 Antibody (YA4751) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to BMAL1.

HY-P86191

	BMAL1 Antibody (YA5883) ARNTL; BHLHE5; BMAL1; MOP3; PASD3; aryl hydrocarbon receptor nuclear translocator-like protein 1; Basic-helix-loop-helix-PAS protein MOP3; Brain and muscle ARNT-like 1Class E basic helix-loop-helix protein 5; bHLHe5; Member of PAS protein 3; PAS domain-containing protein 3; bHLH-PAS protein JAP3	WB, IHC-P, ICC/IF, IP, ELISA	Human, Mouse, Rat
	BMAL1 Antibody (YA5883) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to BMAL1.

HY-P81245

	Cytochrome P450 1A2 Antibody (YA3505) Cytochrome P450 1A2; cytochrome P450, family 1, subfamily a, polypeptide 2; Cytochrome P450 family 1 polypeptide 2; Cytochrome P450 subfamily I aromatic compound inducible polypeptide 2; Cyp1a2; CYPD45; P-450d; RATCYPD45; CP12; CP 12; P3-450; aryl hydrocarbon hydroxylase; Dioxin inducable P3 45; Flavoprotein linked monooxygenase; Microsomal monooxygenase; P450 4; P450 form 4; P450 P3; P450(PA); Xenobiotic monooxygenase; P450 1A2.	WB, ICC/IF, FC	Human
	Cytochrome P450 1A2 Antibody (YA3505) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Cytochrome P450 1A2.

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Cat. No.	Product Name		Classification

HY-151662

4-Azido-2,3,5,6-tetrafluorobenzoic Acid N3-TFBA		Azide
4-Azido-2,3,5,6-tetrafluorobenzoic Acid (N3-TFBA) is a click chemistry reagent containing an azide group. 4-Azido-2,3,5,6-tetrafluorobenzoic Acid is a complex with FAM-labeled DNA probe. 4-Azido-2,3,5,6-tetrafluorobenzoic Acid can be used as versatile photoaffinity labeling agents to probe biological receptors. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

HY-120832

Azt-pmap		Azide
Azt-pmap, a nucleoside analogue, is an aryl phosphate derivative of AZT. Azt-pmap shows anti-HIV activity . AZT is a nucleoside reverse transcriptase inhibitor (NRTI) for HIV infection . Azt-pmap is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-131452

1-Ethynylpyrene		Alkynes
1-Ethynylpyrene is an aryl acetylenic inhibitor of cytochromes P450 1A1, 1A2, and 2B1 with IC₅₀s of 0.18, 0.32, and 0.04 μM, respectively . 1-Ethynylpyrene is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-151749

N3-D-Lys(Fmoc)-OH		Azide
N3-D-Lys(Fmoc)-OH is a click chemistry reagent containing an azide group. Click chemistry is a powerful chemical reaction with excellent bioorthogonality features: biocompatible, rapid and highly specific in biological environments . N3-D-Lys(Fmoc)-OH is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-151736

N3-L-Dap(Boc)-OH		Azide
N3-L-Dap(Boc)-OH is a click chemistry reagent containing an azide group. Click chemistry is a powerful chemical reaction with excellent bioorthogonality features: biocompatible, rapid and highly specific in biological environments . N3-L-Dap(Boc)-OH is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-151744

N3-TFBA-O2Oc		Azide Labeling and Fluorescence Imaging
N3-TFBA-O2Oc is a click chemistry reagent containing an azide group and an aryl group. Aryl azides are well-known precursors of nitrenes and have been introduced by Fleet et al. as versatile photoaffinity labeling agents to probe biological receptors. This type of compounds has been used as photo-cross linker (λ_max=258 nm) in estrogen receptor studies and for direct surface coating of carbon and organic based polymers . N3-TFBA-O2Oc is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-155505

AHR agonist 4		Alkynes
AHR agonist 4 (compound 24e) is an agonist of Aryl hydrocarbon receptor (AHR), assocaited with the immune balance of Th17/22 and Treg cells. AHR agonist 4 serves as a lead compound for anti-psoriasis drug, alleviates imiquimod (IMQ)-induced psoriasis-like skin lesion . AHR agonist 4 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-175421

ArMan		Alkynes
ArMan is an aryl mannoside ligand that can be chemically functionalized onto the surface of virus-like particles (VLPs) through click chemistry. VLPs can be used to target DC-SIGN dendritic cells, promote the selective co-binding of DC-SIGN and TLR7, and lead to a Th1-type immune response. VLP-ArMan-OvaI/II can significantly inhibit tumor growth in the mouse melanoma model .

Targets Recommended: Aryl Hydrocarbon Receptor

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-15001G

Stemregenin 1 SR1	Aryl Hydrocarbon Receptor	Cancer
Stemregenin 1 (SR1) (GMP) is a GMP-grade Stemregenin 1 (HY-15001). GMP-grade small molecules can be used as adjuvants in cell therapy. Stemregenin 1 is a potent aryl hydrocarbon receptor (AhR) antagonist with an IC₅₀ of 127 nM. Stemregenin 1 (GMP) can competitively bind to AhR and inhibit its nuclear translocation, inhibiting osteoclastogenesis and promoting hematopoietic progenitor cell expansion by blocking the AhR-c-src-NF-κB/p-ERK MAPK-NFATc1 signaling pathway. Stemregenin 1 (GMP) can be used for the study of osteoporosis, in vitro expansion of hematopoietic stem cells, and the study of the mechanism of bone metabolic diseases .

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