418 Results for "

bioactive compound

" in MedChemExpress (MCE) Product Catalog:
Products (418)

418 Results for "bioactive compound" in MCE Product Catalog:

10
10 Publications Verification
Art. -Nr.: HY-N0234
CAS. Nr.: 19879-30-2
Synonyms: 7-O-Methylbavachin; Bavachinin A
Bavachinin is agonist of pan-peroxisome proliferator-activated receptor (PPAR), with the IC50 value of 21.043 μM, 12.819 μM, and 0.622 μM to PPAR-α, RRAR-β/δ, and PPAR-γ, respectively. Bavachinin is an inhibitor of HIF-1α. Bavachinin exhibits antitumor activity against non-small cell lung cancer by targeting RRAR-γ. Bavachinin is a natural compound with anti-inflammatory and anti-angiogenic activities. Bavachinin has orally bioactivity. .
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5
5 Cited Publications
Art. -Nr.: HY-N4314
CAS. Nr.: 1168-42-9
Synonyms: 4',5,6,7-Tetramethoxyflavone
Scutellarein tetramethyl ether (4',5,6,7-Tetramethoxyflavone) is a bioactive compound extracted from Eupatorium odoratum. Scutellarein tetramethyl ether exhibits anti-inflammatory, antibacterial, pro-coagulant, and anti-tumor activities. Scutellarein tetramethyl ether exerts its anti-inflammatory effects by modulating the NF-κB pathway and regulates bacterial resistance through the inhibition of efflux pumps. Additionally, Scutellarein tetramethyl ether accelerates coagulation time via the endogenous coagulation pathway. Studies have shown that Scutellarein tetramethyl ether can effectively inhibit the growth of the liver cancer cell line HepG2 (IC50= 20.08 μg/mL) .
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4
4 Cited Publications
Art. -Nr.: HY-N0327
CAS. Nr.: 129277-38-9
Lobetyolin, a bioactive compound, is derived from Codonopsis pilosula. Lobetyolin has anti-inflammatory, anti-oxidative and xanthine oxidase inhibiting activities. Lobetyolin also induces the apoptosis via the inhibition of ASCT2-mediated glutamine metabolism . Lobetyolin is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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3
3 Cited Publications
Art. -Nr.: HY-N0609
CAS. Nr.: 104-55-2
Cinnamaldehyde is a major and a bioactive compound isolated from the leaves of Cinnamomum osmophloeum kaneh. Cinnamaldehyde is a cytokine production inhibitor. Cinnamaldehyde has anti-bacteria, anti-oxidation, and anti-inflammatory properties .
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3
3 Cited Publications
Art. -Nr.: HY-N6064
CAS. Nr.: 66663-91-0
Polygalacin D (PGD) is a bioactive compound isolated from Platycodon grandiflorum with anticancer and anti-proliferative properties. PGD suppresses the expression of the IAP family of proteins including survivin, cIAP-1 and cIAP-2 and blocks the PI3K/Akt pathway by inhibiting the phosphorylation of GSK3β, Akt and the expression of PI3K. Polygalacin D induces apoptosis
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2
2 Cited Publications
Art. -Nr.: HY-N9388
CAS. Nr.: 82209-74-3
Andrograpanin, a bioactive compound from Andrographis paniculata, exhibits anti-inflammatory and anti-infectious properties .
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2
2 Cited Publications
Art. -Nr.: HY-N1990
CAS. Nr.: 94987-08-3
Gypenoside XLIX is a multifunctional bioactive compound that can be isolated from Gynostemma pentaphyllum, with a Ka value of 1.58 μM for its binding to SIRT1. Gypenoside XLIX acts as a PPAR-α agonist. It inhibits the activation of TLR4-mediated NF-κB signaling pathway by activating the Sirt1/Nrf2 signaling pathway, reduces ROS accumulation, and alleviates hepatic inflammatory injury in mice with sepsis-induced liver disease. Gypenoside XLIX targets SIRT1 to block YAP-NLRP3 activation and improve sepsis-induced cardiomyopathy. Gypenoside XLIX inhibits apoptosis (Apoptosis), pyroptosis (Pyroptosis), autophagy (Autophagy), lipid peroxidation, pro-inflammatory cytokines and anti-inflammatory cytokines. Gypenoside XLIX alleviates sepsis-induced splenic injury by inhibiting inflammation and oxidative stress, and mitigates sepsis-associated encephalopathy by targeting PPAR-α. Gypenoside XLIX prevents acute kidney injury by inhibiting IGFBP7/IGF1R-mediated programmed cell death and inflammation. Gypenoside XLIX inhibits the expression and activity of vascular cell adhesion molecule-1 in cytokine-induced human endothelial cells. Gypenoside XLIX is applicable to research related to acute liver injury, lung injury, cardiomyopathy, acute splenic injury, sepsis-associated encephalopathy, acute kidney injury, atherosclerosis and chronic inflammation .
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1
1 Cited Publications
Art. -Nr.: HY-129328
CAS. Nr.: 14783-68-7
Reinheit:  ≥98.0%
Synonyms: Magnesium bisglycinate; Magnesium diglycinate
Forschungsgebiete:  

Cancer

Magnesium glycinate (Magnesium bisglycinate), the magnesium salt of glycine, is a nutrient supplement. Magnesium glycinate has satisfactory physico-chemical properties and bioactivities. Metal glycinate chelates are formed by glycine and metal compounds through chemical reactions. Magnesium is an essential mineral that plays a critical role in the human body. Magnesium takes part in the process of energy metabolism and assists the maintenance of normal muscle function .
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1
1 Cited Publications
Art. -Nr.: HY-139066
CAS. Nr.: 544-72-9
Reinheit:  ≥98.0%
Synonyms: Trichosanic acid
Punicic acid is a bioactive compound of pomegranate seed oil. Punicic acid is an isomer of conjugated α-linolenic acid and ω-5 polyunsaturated fatty acids. Punicic acid has anti-inflammatory and antioxidant activities and can inhibit the expression of inflammatory mediators such as tumor necrosis factor α (TNF-α). Punicic acid can also reduce the formation of β-amyloid deposits and hyperphosphorylation of tau by increasing the expression of GLUT4 protein and inhibiting the overactivation of calpain, and is used to prevent and treat neurodegenerative diseases. In addition, punicic acid also has breast cancer inhibitor properties that depend on lipid peroxidation and PKC pathways .
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Art. -Nr.: HY-W054292
CAS. Nr.: 1025796-31-9
Synonyms: (OtBu)KuE(OtBu)2
Tert-Butyl-DCL is a PSMA inhibitor. Tert-Butyl-DCL Tert-Butyl-DCL can be used in the research of prostate cancer .
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Art. -Nr.: HY-N2896
CAS. Nr.: 465-00-9
Arjunolic acid is an orally active, multifunctional bioactive compound. Arjunolic acid exhibits free radical scavenging activity, as well as fungal and bacterial activities. Arjunolic acid induces apoptosis (Apoptosis) in various cancer cells. Arjunolic acid protects hepatocytes against induced oxidative stress and apoptosis by reducing reactive oxygen species and inhibiting NF-κB activation. Arjunolic acid regulates pancreatic dysfunction in type 2 diabetic rats by blocking the activation of the TLR-4/MyD88 and canonical Wnt pathways. Arjunolic acid inhibits neuroinflammation and ameliorates depressive behaviors via the SIRT1/AMPK/Notch1 signaling pathway in microglia. Arjunolic acid improves Crohn's disease-like colitis by restoring gut microbiota composition and inhibiting TLR4 signaling. Arjunolic acid suppresses osteosarcoma progression by inhibiting Wnt3a-mediated M2 polarization of macrophages. Arjunolic acid ameliorates diabetic retinopathy via the autophagy pathway regulated by AMPK/mTOR/HO-1. Arjunolic acid is applicable to research related to type 2 diabetes, organ toxicity, depression, Crohn's disease, osteosarcoma, diabetic retinopathy, and testicular dysfunction .
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Art. -Nr.: HY-W019358
CAS. Nr.: 612-20-4
2-Hydroxymethyl benzoic acid serves as an effective water substitute in the Passerini reaction. 2-Hydroxymethyl benzoic acid can be used for the synthesis of α-hydroxyamides, which are molecular building blocks for the synthesis of bioactive compounds .
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Art. -Nr.: HY-N7195
CAS. Nr.: 60124-17-6
12-Deoxywithastramonolide is a principle bioactive compound found in ashwagandha (W. somnifera). 12-Deoxywithastramonolide possesses antioxidant and enzyme inhibitory effects .
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Art. -Nr.: HY-N0357
CAS. Nr.: 873001-54-8
3,29-Dibenzoyl rarounitriol is one major bioactive compound of multiflorane triterpene esters Trichosanthes kirilowii, can be chosen as the marker for quantitation of Trichosanthes kirilowii .
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Art. -Nr.: HY-W004801
CAS. Nr.: 4687-25-6
Target:  

Drug Intermediate

Forschungsgebiete:  

Others

Benzofuran-3-carbaldehyde is a bioactive chemical, and can be used for the synthesis of active compound .
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Art. -Nr.: HY-W094994
CAS. Nr.: 244-76-8
Synonyms: alpha-Carboline
Target:  

Drug Intermediate

Forschungsgebiete:  

Others

α-carboline (alpha-Carboline) is a promising scaffold compound for medicinal chemistry. α-carboline natural products and their derivatives possess diverse bioactivities .
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Art. -Nr.: HY-122496
CAS. Nr.: 643-84-5
Reinheit:  98.48%
Synonyms: Syringidin
Malvidin (chloride) is a bioactive compound isolated from grape. Malvidin shows cytotoxicity through the arrest of the G2/M phase of cell cycle and induction of apoptosis. Malvidin can be used for the research of cancer .
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Art. -Nr.: HY-W002168
CAS. Nr.: 694-48-4
1,3-Dimethylpyrazole is a bioactive compound isolated from Moso Bamboo Root .
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Art. -Nr.: HY-101580
CAS. Nr.: 188396-77-2
Reinheit:  96.26%
Synonyms: SR 57667
Target:  

Drug Derivative

Forschungsgebiete:  

Neurological Disease

Paliroden is an orally bioactive neurotrophic, non-peptidic compound that activates synthesis of endogenous neurotrophines, used for treatment of Alzheimer's Disease and Parkinson's.
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Art. -Nr.: HY-W011048
CAS. Nr.: 24038-68-4
Synonyms: BisOPP-A
Target:  

Drug Intermediate

Forschungsgebiete:  

Others

2,2-Bis(3-phenyl-4-hydroxyphenyl)propane (BisOPP-A) is a bioactive chemical, and can be used for the synthesis of active compound .
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