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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
143 Results for "
human kidney
" in MedChemExpress (MCE) Product Catalog:
Products (143)
143 Results for "human kidney" in MCE Product Catalog:
29
Category:
Rosaceae Extract Plants Dihydrochalcones Endogenous metabolite Human Gut Microbiota Metabolites Flavonoids Microorganisms Malus pumila Mill. Phenols Polyphenols Disease Research Fields Cancer
Target:
19
19 Cited Publications
Synonyms: Matridin-15-one; Vegard; α-Matrine
4
4 Cited Publications
Cat. No.: HY-B0735A
CAS No.: 67227-57-0
Synonyms: Fenoldopam methanesulfonate; SKF-82526 mesylate
Target:
Research Areas:
Cardiovascular Disease Inflammation/Immunology Endocrinology Cancer
Fenoldopam (SKF-82526) mesylate is a selective dopamine D1 receptor agonist. Fenoldopam mesylate binds to rat D1B dopamine receptors (Kd = 11 nM) and human D1A receptors (Kd = 17 nM) in COS-7 cell membranes expressing the cloned receptors. Fenoldopam mesylate modulates dopamine receptor expression, induces vasorelaxation in vascular tissues, reverses glomerular hyperfiltration in rat models, increases intracellular cAMP levels, promotes DARPP-32 phosphorylation in small cell lung cancer (SCLC) cells, inhibits cytokine secretion, and downregulates T cell activation markers in activated human T cells. Fenoldopam mesylate can be used for research on hypertension, acute kidney injury, psoriasis, and small cell lung cancer .
2
Target:
Research Areas:
2
2 Cited Publications
Cat. No.: HY-P0254
CAS No.: 374675-21-5
Target:
Research Areas:
2
2 Cited Publications
Cat. No.: HY-P0254A
Target:
Research Areas:
2
2 Cited Publications
Target:
Research Areas:
ARC 239 is an α2B/C-adrenergic receptor antagonist with pKi of 7.06 and 6.95 for rat kidney α2B and human α2C, respectively. ARC 239 also inhibits 5-HT1A receptor with a Ki of 63.1 nM .
2
2 Cited Publications
Cat. No.: HY-P7880
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: ALPL; Alkaline Phosphatase, Liver/Bone/kidney; Prev. HOPS; TNS-ALP; TNSALP; Liver/Bone/kidney-Type Alkaline Phosphatase; Alkaline Phosphatase, Tissue-Nonspecific Isozyme; Tissue-Nonspecific ALP; Alkaline Phosphatase Liver/Bone/kidney Isozyme; Alkaline Pho
Species:
Human
Source:
HEK293
2
2 Cited Publications
Cat. No.: HY-P700138AF
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: MDK; Midgestation And kidney Protein; Prev. NEGF2; ARAP; MK; Neurite Outgrowth-Promoting Protein; Neurite Outgrowth-Promoting Factor 2; Retinoic Acid Inducible Factor; Neurite Growth-Promoting Factor 2; Mutant Truncated Midkine B; Amphiregulin-Associated
Species:
Human
Source:
E. coli
2
2 Cited Publications
Cat. No.: HY-N1990
CAS No.: 94987-08-3
1
Target:
Research Areas:
1
1 Cited Publications
Cat. No.: HY-163121
CAS No.: 1096144-06-7
Research Areas:
PST3.1a is an orally active and brain-penetrant N-acetylglucosamine glycosyltransferase (MGAT5) inhibitor with a human IC50 of 2 µM. PST3.1a inhibits TGFβR and FAK signaling pathway activity. PST3.1a alters β1,6-GlcNAc N-glycans and microtubule/microfilament integrity, increases OLIG2 expression, and inhibits proliferation, migration, invasiveness, and clonogenic capacities of glioblastoma initiating cells. PST3.1a reduces invasive and proliferative capacity of glioblastoma initiating cells in orthotopic graft models, increases overall survival of orthotopic graft model mice. PST3.1a blunts MGAT5 overexpression, decreases renal fibrosis via collagen 1, collagen 4, and galectin 3 downregulation in a rat chronic kidney disease model. PST3.1a can be used for the research of glioblastoma multiforme and chronic kidney disease .
1
1 Cited Publications
Cat. No.: HY-P73295
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: MDK; Midgestation And kidney Protein; Prev. NEGF2; ARAP; MK; Neurite Outgrowth-Promoting Protein; Neurite Outgrowth-Promoting Factor 2; Retinoic Acid Inducible Factor; Neurite Growth-Promoting Factor 2; Mutant Truncated Midkine B; Amphiregulin-Associated
Species:
Human
Source:
Sf9 insect cells
1
1 Cited Publications
Cat. No.: HY-P700791
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: MDK; Midgestation And kidney Protein; Prev. NEGF2; ARAP; MK; Neurite Outgrowth-Promoting Protein; Neurite Outgrowth-Promoting Factor 2; Retinoic Acid Inducible Factor; Neurite Growth-Promoting Factor 2; Mutant Truncated Midkine B; Amphiregulin-Associated
Species:
Human
Source:
E. coli
1
1 Cited Publications
Cat. No.: HY-N0805A
CAS No.: 18649-93-9
Category:
Triterpenes Alisma plantago-aquatica Linn. Terpenoids Metabolic Disease Plants Disease Research Fields Alismataceae Extract
Target:
1
1 Cited Publications
Cat. No.: HY-P72683
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CXCL14; Kec; Prev. SCYB14; Small Inducible Cytokine Subfamily B (Cys-X-Cys), Member 14 (BRAK); NJAC; Chemokine (C-X-C Motif) Ligand 14; Small-Inducible Cytokine B14; Breast And kidney; C-X-C Motif Chemokine 14; MIP-2G; Chemokine BRAK; MIP2G; Bolekine; CXC
Species:
Human
Source:
E. coli
1
1 Cited Publications
Cat. No.: HY-P81703
Synonyms: CD366 antibody;
FLJ14428 antibody;
HAVcr-2 antibody;
Havcr2 antibody;
HAVR2_human antibody;
Hepatitis A virus cellular receptor 2 antibody;
kidney injury molecule 3 antibody;
KIM 3 antibody;
KIM3 antibody;
T cell immunoglobulin and mucin domain containing 3 antibody;
T cell immunoglobulin mucin 3 antibody;
T-cell immunoglobulin and mucin domain-containing protein 3 antibody;
T-cell immunoglobulin mucin family member 3 antibody;
T-cell immunoglobulin mucin receptor 3 antibody;
T-cell membrane protein 3 antibody;
Tim 3 antibody;
TIM-3 antibody;
TIM3 antibody;
TIMD-3 antibody;
TIMD3 antibody;
Research Areas:
Rilmenidine, an innovative antihypertensive agent, is an orally active, selective I1 imidazoline receptor agonist. Rilmenidine is an alpha 2-adrenoceptor agonist. Rilmenidine induces autophagy. Rilmenidine acts both centrally by reducing sympathetic overactivity and in the kidney by inhibiting the Na +/H + antiport. Rilmenidine modulates proliferation and stimulates the proapoptotic protein Bax thus inducing the perturbation of the mitochondrial pathway and apoptosis in human leukemic K562 cells .
Cat. No.: HY-P99505
CAS No.: 2226654-05-1
Synonyms: COR-001; MEDI-5117; MEDI-5117; NN-6018; WBP-216
Target:
Research Areas:
Cat. No.: HY-P99152
CAS No.: 140608-64-6
Synonyms: Muromanab-CD3
Target:
Research Areas:
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
