160 Results for "

hypoglycemic

" in MedChemExpress (MCE) Product Catalog:
Products (160)

160 Results for "hypoglycemic" in MCE Product Catalog:

13
13 Publications Verification
Cat. No.: HY-N0820
CAS No.: 2415-24-9
Synonyms: Catalpinoside
Catalpol (Catalpinoside), an iridoid glycoside found in Rehmannia glutinosa. Catalpol has neuroprotective, hypoglycemic, anti-inflammatory, anti-cancer, anti-spasmodic, anti-oxidant effects and anti-HBV effects .
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13
13 Publications Verification
Cat. No.: HY-B0089
CAS No.: 56180-94-0
Synonyms: BAY g 5421
Acarbose (BAY g 5421), antihyperglycemic agent, is an orally active alpha-glucosidase inhibitor (IC50=11 nM). Acarbose can potentiate the hypoglycemic effects of sulfonylureas or insulin .
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13
13 Publications Verification
Cat. No.: HY-N0416
CAS No.: 6199-67-3
Cucurbitacin B belongs to a class of highly oxidized tetracyclic triterpenoids and is oral active. Cucurbitacin B inhibits tumor cell growth, migration and invasion and cycle arrest, but induces cell apoptosis. Cucurbitacin B has potent anti-inflammatory, antioxidant, antiviral, hypoglycemic, hepatoprotective, neuroprotective activity .
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12
12 Cited Publications
Cat. No.: HY-Y0337
CAS No.: 52-90-4
Synonyms: Cysteine
L-Cysteine (Cysteine) is an orally active conditionally essential amino acid with hypoglycemic effects, which acts as a precursor for biologically active molecules such as hydrogen sulphide (H2S), glutathione and taurine. L-Cysteine promotes the proliferation and differentiation of neural stem cells via the CBS/H2S pathway. L-Cysteine suppresses ghrelin and reduces appetite in rodents and humans. L-Cysteine can be used as an anorectic agent .
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11
11 Cited Publications
Cat. No.: HY-16397
CAS No.: 114-86-3
Synonyms: Phenethylbiguanide
Phenformin (Phenethylbiguanide) is an orally active biguanide hypoglycemic agent. Phenformin inhibits mitochondrial respiratory chain complex I, leading to an increased AMP/ATP ratio, activation of AMPK, and subsequent inhibition of the mTOR pathway, thereby suppressing cell proliferation, inducing apoptosis and autophagy. Phenformin inhibits cancer stem cells (CSCs) and possesses potent antitumor potential .
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11
11 Cited Publications
Cat. No.: HY-16397A
CAS No.: 834-28-6
Synonyms: Phenethylbiguanide hydrochloride
Phenformin (Phenethylbiguanide) hydrochloride is an orally active biguanide hypoglycemic agent. Phenformin hydrochloride inhibits mitochondrial respiratory chain complex I, leading to an increased AMP/ATP ratio, activation of AMPK, and subsequent inhibition of the mTOR pathway, thereby suppressing cell proliferation, inducing apoptosis and autophagy. Phenformin hydrochloride inhibits cancer stem cells (CSCs) and possesses potent antitumor potential .
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10
10 Cited Publications
Cat. No.: HY-128923
CAS No.: 320386-54-7
Purity:  96.35%
Synonyms: 3-Mercaptopicolinic acid hydrochloride; 3-MPA hydrochloride
Target:  

PEPCK

Research Areas:  

Metabolic Disease

SKF-34288 (3-Mercaptopicolinic acid) hydrochloride is an orally active phosphoenolpyruvate carboxykinase (PEPCK) inhibitor (Ki: 2-9 μM). SKF-34288 hydrochloride is a potent hypoglycemic agent by inhibiting glucose synthesis. SKF-34288 hydrochloride also inhibits Asn metabolism and increases amino acids and amides .
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9
9 Cited Publications
Cat. No.: HY-N6653
CAS No.: 37339-90-5
Lentinan is an orally active biocompatible multifunctional polysaccharide with biological activities such as anti-inflammatory, antioxidant, immune regulation, anti-tumor, hypoglycemic, and lipid-lowering [1][4].
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6
6 Cited Publications
Cat. No.: HY-N0205
CAS No.: 129741-57-7
Synonyms: Anemoside B4
Pulchinenoside C (Anemoside B4) is Pulsatilla koreana Nakai that have many numerous biological effects in vitro, including enhancing hypoglycemic, anti-tumor, neuroprotective and anti-angiogenic activity.
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4
4 Cited Publications
Cat. No.: HY-B1429
CAS No.: 94-20-2
Target:  

Na+/K+ ATPase

Research Areas:  

Metabolic Disease Endocrinology

Chlorpropamide is an oral hypoglycemic agent that can influence acetaldehyde metabolism in mice and has a potentiating effect on antidiuretic hormone .
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3
3 Cited Publications
Cat. No.: HY-N0661
CAS No.: 556-27-4
Alliin, an orally active sulfoxide compound that can be isolated from garlic, exhibits hypoglycemic, antioxidant, anti-inflammatory and antitumor activities .
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3
3 Cited Publications
Cat. No.: HY-N2229
CAS No.: 500-65-2
Rhapontigenin is a natural analog of resveratrol with anticancer, antioxidant, antifungal and antibacterial activities. Rhapontigenin is amechanism-based, potent and selective cytochrome P450 1A1 inactivator (IC50  = 400 nM). Rhapontigenin exhibits 400-fold and 23-fold selectivity for P450 1A1 over P450 1A2 and P450 1B1, respectively .
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3
3 Cited Publications
Cat. No.: HY-N0761
CAS No.: 537-73-5
Synonyms: 3-Hydroxy-4-methoxycinnamic acid
Isoferulic acid (3-Hydroxy-4-methoxycinnamic acid) is an orally active cinnamic acid derivative. Isoferulic acid exhibits hypoglycemic, antiviral, and antioxidant activities. Isoferulic acid can also inhibit fructose- and glucose-mediated protein glycation. Isoferulic acid can be used in the research of diseases such as diabetes .
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2
2 Cited Publications
Cat. No.: HY-N4195
CAS No.: 38963-95-0
Synonyms: Resveratrol glycoside; trans-Resveratrol 4'-O-β-D-glucopyranoside
Resveratroloside (Resveratrol glycoside) is an orally active competitive inhibitor of α-glucosidase. Resveratroloside has hypoglycemic and cardioprotective effects. Resveratroloside can be used for the research of diabetes and heart system diseases .
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2
2 Cited Publications
Cat. No.: HY-N5083
CAS No.: 20310-89-8
Saponarin is an orally active flavonoid compound. Saponarin can be isolated from Gypsophila trichotoma. Saponarin inhibits ERK/p38, NF-κB and MAPK phosphorylation and activates AMPK. Saponarin reduces IL-1β and COX-2. Saponarin has antioxidant, anti-inflammatory, hepatoprotective, hypoglycemic and hypotensive effects. Saponarin improves sleep disorders .
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1
1 Cited Publications
Cat. No.: HY-P4860
CAS No.: 1802086-30-1
Target:  

Akt Gli JNK PKA

Research Areas:  

Metabolic Disease

Adropin (34-76) is a secretory domain of Adropin. Adropin (34-76) can inhibit cAMP level and glucose production in hepatocytes, and has a hypoglycemic effect. Adropin (34-76) plays an antifibrotic role by inhibiting the GLI1 signaling pathway .
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1
1 Cited Publications
Cat. No.: HY-N0926
CAS No.: 3621-36-1
Synonyms: Columbamin; Dehydroisocorypalmine
Columbamine (Columbamin; Dehydroisocorypalmine) is an organic heterotetracyclic alkaloid extracted from plants. Columbamine is a metabolite of Berberine (HY-N0716). Columbamine inhibits the cytochrome P450 (CYP) isoform CYP3A4 (IC50 = 30.6 µM). Columbamine induces apoptosis in cancer cells. Columbamine can be used for antioxidant, anti-inflammatory, antitumor, antifungal, antiparasite, hepatoprotective, neuroprotective, hypolipidemic and hypoglycemic study .
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1
1 Cited Publications
Cat. No.: HY-N0655
CAS No.: 10284-63-6
Synonyms: 3-O-Methyl-D-chiro-inositol
D-pinitol (3-O-Methyl-D-chiro-inositol) is a natural compound presented in several plants, like Pinaceae and Leguminosae plants. D-pinitol exerts hypoglycemic activity and protective effects in the cardiovascular system . D-pinitol has antiviral and larvicidal activities .
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1
1 Cited Publications
Cat. No.: HY-N8264
CAS No.: 73255-40-0
Moringin is a potent and selective TRPA1 ion channel natural agonist with an EC50 of 3.14 μM. Moringin does not activate or activates very weakly the vanilloids somatosensory channels TRPV1, TRPV2, TRPV3 and TRPV4, and the melastatin cooling receptor TRPM8. Moringin has hypoglycemic, antimicrobial, anti-inflammatory, anticancer and neuroprotection activities .
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