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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
156 Results for "
hypoglycemic
" in MedChemExpress (MCE) Product Catalog:
Products (156)
156 Results for "hypoglycemic" in MCE Product Catalog:
46
Target:
Exendin (9-39) amide (Avexitide) is a competitive GLP-1R antagonist. Exendin (9-39) amide blocks the Semaglutide (HY-114118)-induced increase in insulin secretion and also attenuates the hypoglycemic effect of Semaglutide. Exendin (9-39) amide abolishes the islet-protective effect of Liraglutide. Exendin (9-39) amide can be used in research on type 2 diabetes and type 1 diabetes .
46
Target:
Research Areas:
Exendin (9-39) amide acetate (Avexitide acetate) is a competitive GLP-1R antagonist. Exendin (9-39) amide acetate blocks the Semaglutide (HY-114118)-induced increase in insulin secretion and also attenuates the hypoglycemic effect of Semaglutide. Exendin (9-39) amide acetate abolishes the islet-protective effect of Liraglutide. Exendin (9-39) amide acetate can be used in research on type 2 diabetes and type 1 diabetes .
15
Category:
Polysaccharides Microorganisms Anti-aging Metabolic Disease Disease Research Fields Saccharides
Target:
14
Category:
Neurological Disease Anti-aging Plants Rehmannia glutinosa (Gaert.) Libosch. ex Fisch. et Mey Infection Iridoids Terpenoids Scrophulariaceae Extract Disease Research Fields Inflammation/Immunology Cancer
Target:
13
13
11
11 Cited Publications
Synonyms: Phenethylbiguanide hydrochloride
Research Areas:
Phenformin (Phenethylbiguanide) hydrochloride is an orally active biguanide hypoglycemic agent. Phenformin hydrochloride inhibits mitochondrial respiratory chain complex I, leading to an increased AMP/ATP ratio, activation of AMPK, and subsequent inhibition of the mTOR pathway, thereby suppressing cell proliferation, inducing apoptosis and autophagy. Phenformin hydrochloride inhibits cancer stem cells (CSCs) and possesses potent antitumor potential .
11
Research Areas:
Phenformin (Phenethylbiguanide) is an orally active biguanide hypoglycemic agent. Phenformin inhibits mitochondrial respiratory chain complex I, leading to an increased AMP/ATP ratio, activation of AMPK, and subsequent inhibition of the mTOR pathway, thereby suppressing cell proliferation, inducing apoptosis and autophagy. Phenformin inhibits cancer stem cells (CSCs) and possesses potent antitumor potential .
10
10 Cited Publications
Synonyms: 3-Mercaptopicolinic acid hydrochloride; 3-MPA hydrochloride
Target:
Research Areas:
SKF-34288 (3-Mercaptopicolinic acid) hydrochloride is an orally active phosphoenolpyruvate carboxykinase (PEPCK) inhibitor (Ki: 2-9 μM). SKF-34288 hydrochloride is a potent hypoglycemic agent by inhibiting glucose synthesis. SKF-34288 hydrochloride also inhibits Asn metabolism and increases amino acids and amides .
9
9 Cited Publications
Cat. No.: HY-N6653
CAS No.: 37339-90-5
Category:
Polysaccharides Agaricaceae Extract Lentinus edodes (Berk. ) Sing Plants Disease Research Fields Saccharides Cancer
Target:
4
Target:
Research Areas:
Chlorpropamide is an oral hypoglycemic agent that can influence acetaldehyde metabolism in mice and has a potentiating effect on antidiuretic hormone .
3
Category:
Cardiovascular Disease Ketones, Aldehydes, Acids Plants Liliaceae Extract Disease Research Fields A．Sativam L. var．Viviparum Regel
Target:
3
3 Cited Publications
Synonyms: 3-Hydroxy-4-methoxycinnamic acid
3
3 Cited Publications
Cat. No.: HY-N5083
CAS No.: 20310-89-8
2
2 Cited Publications
Cat. No.: HY-N4195
CAS No.: 38963-95-0
Synonyms: Resveratrol glycoside; trans-Resveratrol 4'-O-β-D-glucopyranoside
Category:
Cardiovascular Disease Stilbenes Reynoutria japonica Houtt. Phenols Polyphenols Plants Disease Research Fields Polygonaceae Extract
Target:
2
2 Cited Publications
Synonyms: Columbamin; Dehydroisocorypalmine
Target:
2
2 Cited Publications
Synonyms: Columbamin chloride; Dehydroisocorypalmine chloride
Target:
1
Category:
Human Gut Microbiota Metabolites Polysaccharides Metabolic Disease Plants Endogenous metabolite Disease Research Fields Albizia glaberrima (Schumach. & Thonn.) Benth. Saccharides Labiatae Extract
Target:
1
1 Cited Publications
Cat. No.: HY-P4860
CAS No.: 1802086-30-1
Research Areas:
1
Category:
Cardiovascular Disease Natural Products Glycine max (L.) merr Leguminosae Extract Plants Disease Research Fields Inflammation/Immunology
Target:
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
