72 Results for "

protect amino acids

" in MedChemExpress (MCE) Product Catalog:
Products (72)

72 Results for "protect amino acids" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-W009749
CAS No.: 56-88-2
L-Cystathionine is a nonprotein thioether and is a key amino acid associated with the metabolic state of sulfur-containing amino acids. L-Cystathionine protects against Homocysteine-induced mitochondria-dependent apoptosis of vascular endothelial cells (HUVECs). L-Cystathionine plays an important role in cardiovascular protection .
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1
1 Cited Publications
Cat. No.: HY-41121
CAS No.: 15761-38-3
Synonyms: Boc-Ala-OH
Research Areas:  

Cancer

Boc-L-Ala-OH (Boc-Ala-OH) is a single N-protected amino acid ligand and a protected L-alanine derivative. Boc-L-Ala-OH promotes Pd (II)-catalyzed enantioselective C-H alkenylation and kinetic resolution. Boc-L-Ala-OH serves as a coupling reagent for the synthesis of liver-targeted glycogen phosphorylase inhibitors and P6A metabolites, and also acts as a negative control in synthesis studies of betulinic acid amino acid esters. Boc-L-Ala-OH is applicable to research on epidermoid squamous cell carcinoma .
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1
1 Cited Publications
Cat. No.: HY-W009749C
CAS No.: 61125-50-6
L-Cystathionine (dihydrochloride) is a nonprotein thioether and is a key amino acid associated with the metabolic state of sulfur-containing amino acids. L-Cystathionine (dihydrochloride) protects against Homocysteine-induced mitochondria-dependent apoptosis of vascular endothelial cells (HUVECs). L-Cystathionine (dihydrochloride) plays an important role in cardiovascular protection .
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Cat. No.: HY-79647
CAS No.: 82911-69-1
Synonyms: N-(Fmoc-oxy)succinimide
Fmoc-OSu (N-(Fmoc-oxy)succinimide) is an acylating agent that targets amino groups (-NH2). It can selectively protect the amino groups of amino acids by covalently binding with primary or secondary amines through nucleophilic substitution reactions. Fmoc-OSu forms a stable amide bond with the amino group to avoid side reactions of the amino group in peptide synthesis. It can also be used as a fluorescent labeling reagent to react with glycosylamines for efficient labeling of N-sugar chains. Fmoc-OSu can be used as an Fmoc protection strategy in peptide synthesis, and as a fluorescent labeling and analysis method for N-sugar chains .
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Cat. No.: HY-W007655
CAS No.: 92122-45-7
Fmoc-D-Lys (Boc)-OH is an Fmoc- and Boc-protected D-lysine derivative. Fmoc-D-Lys (Boc)-OH ensures the precise incorporation of D-lysine into peptide chains, maintaining the specific conformation and biological activity of peptides. Fmoc-D-Lys (Boc)-OH can be used in research on the synthesis of peptides containing unnatural amino acids .
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Cat. No.: HY-78933
CAS No.: 474645-26-6
Research Areas:  

Cancer

Fmoc-MMAE is a protective group-conjugated monomethyl auristatin E (MMAE), which is a potent tubulin inhibitor. Fmoc-MMAE can be used in the synthesis of ADC .
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Cat. No.: HY-W615153
CAS No.: 1662688-20-1
Research Areas:  

Others

Fmoc-L-Lys[Oct-(OtBu)-Glu-(OtBu)-AEEA-AEEA]-OH is an L-Lys (an amino acid) derivative. Fmoc protects amino acids, ensuring their accurate peptide synthesis .
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Cat. No.: HY-W008876
CAS No.: 201531-88-6
Research Areas:  

Others

Fmoc-Pen(Trt)-OH is an amino acid derivative with an Fmoc protecting group that can be used to synthesize the inhibitory cystine knot (ICK) peptide ProTx-II .
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Cat. No.: HY-66007
CAS No.: 3025-95-4
Ac-β-Ala-OH is an abnormal amino acid metabolite and also serves as a mono-N-protected amino acid (MPAA) ligand. Ac-β-Ala-OH supports the β-C (sp 3)-H arylation of aliphatic carboxylic acids and also serves as a starting building block for the reverse MAP core in the construction of the gonorrhea vaccine candidate TMCP2 .
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Cat. No.: HY-W012001
CAS No.: 60142-89-4
Target:  

PROTAC Linkers

Research Areas:  

Cancer

Boc-7-Aminoheptanoic acid can be used as a PROTAC linker in the synthesis of PROTACs and other conjugation applications. Boc-7-Aminoheptanoic acid is an alkane chain with terminal carboxlic acid and Boc-protected amino groups. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The Boc group can be deprotected under mild acidic conditions to form the free amine.
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Cat. No.: HY-W008064
CAS No.: 133174-15-9
Synonyms: Fmoc-L-Citrulline
Research Areas:  

Cancer

Fmoc-Cit-OH (Fmoc-L-Citrulline) is an amino acid derivative with an Fmoc protecting group, which can be used to synthesize a degradable ADC linker composed of a valine-citrulline (Val-Cit) motif .
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Cat. No.: HY-W009118
CAS No.: 123622-48-0
Research Areas:  

Others

Fmoc-5-Ava-OH is an amino acid derivative with an Fmoc protecting group, which can be used to synthesize fatty acid-based dimeric peptides with PSD-95 inhibitory activity .
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Cat. No.: HY-W047788
CAS No.: 10270-94-7
Research Areas:  

Others

H-Dab(Boc)-OH is an amino acid derivative with a Boc protecting group, which can be used to synthesize methotrexate (MTX) analogs with antitumor and antifolate activities .
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Cat. No.: HY-42773
CAS No.: 88829-82-7
Synonyms: 1-Boc-1,8-diaminooctane
Target:  

PROTAC Linkers

Research Areas:  

Cancer

tert-Butyl (8-aminooctyl)carbamate (1-Boc-1,8-diaminooctane) can be used as a PROTAC linker in the synthesis of PROTACs. tert-butyl (8-aminooctyl)carbamate is an alkane chain with terminal amine and Boc-protected amino groups. Amine group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The Boc group can be deprotected under mild acidic conditions to form the free amine.
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Cat. No.: HY-W048697
CAS No.: 201532-01-6
Research Areas:  

Others

Fmoc-D-Pen(Trt)-OH is an amino acid derivative with an Fmoc protecting group, which can be used to synthesize analogs of cyclic lanthionine enkephalin, a δ-opioid receptor selective ligand .
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Cat. No.: HY-W041856
CAS No.: 30100-16-4
Synonyms: Boc-8-aminooctanoic acid
Target:  

PROTAC Linkers

Research Areas:  

Cancer

N-Boc-8-amino-octanoic acid (Boc-8-aminooctanoic acid) can be used as a PROTAC linker in the synthesis of PROTACs. N-Boc-8-amino-octanoic acid is an alkane chain with terminal carboxlic acid and Boc-protected amino groups. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The Boc group can be deprotected under mild acidic conditions to form the free amine.
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Cat. No.: HY-34611
CAS No.: 25691-37-6
Synonyms: N-Boc-L-2,4-diaminobutyric acid; Boc-Dab-OH
Target:  

Drug Intermediate ASCT

Research Areas:  

Neurological Disease Cancer

Boc-L-2,4-Diaminobutyric acid (N-Boc-L-2,4-diaminobutyric acid; Boc-Dab-OH) is a versatile synthetic starting material with a cleavable protecting group. Boc-L-2,4-Diaminobutyric acid not only reduces the backbone cleavage rate by protecting the side-chain γ-amino group, but also triggers intramolecular cyclization of self-immolative linkers under acidic cleavage conditions, thus constructing stimuli-responsive materials. Boc-L-2,4-Diaminobutyric acid is also an important building block for bioactive molecules. It can be used in the synthesis of ASCT2 (SLC1A5) inhibitors and carboxynorspermine, and can also serve as an internal standard to support the quantitative detection of specific intracellular amino acids by UPLC-QQQ-MS .
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Cat. No.: HY-W047688
CAS No.: 216961-61-4
Synonyms: 1-Boc-1,10-diaminodecane
Target:  

PROTAC Linkers

Research Areas:  

Cancer

tert-Butyl (10-aminodecyl) carbamate (1-Boc-1,10-diaminodecane) is a synthetic intermediate that serves as a PROTAC linker in PROTAC synthesis and other conjugation applications. tert-Butyl (10-aminodecyl) carbamate is an alkane chain with a terminal amine and a Boc-protected amino group. The amine group can react with carboxylic acids, active NHS esters, carbonyl groups (ketones, aldehydes), etc. The Boc group can be deprotected under mild acidic conditions to form a free amine .
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Cat. No.: HY-W012000
CAS No.: 52498-32-5
Synonyms: Boc-N-Me-Ile-OH
Target:  

Drug Intermediate

Research Areas:  

Others

Boc-N-methyl-L-isoleucine (Boc-N-Me-Ile-OH) is a Boc-protected N-methylated derivative of L-isoleucine (HY-N0771), as well as a protected amino acid building block .
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Cat. No.: HY-155887
CAS No.: 474922-26-4
Synonyms: DSPE-PEG-NH2, MW 3400 ammonium
Target:  

Liposome

Research Areas:  

Cancer

DSPE-PEG-Amine (DSPE-PEG-NH2), MW 3400 ammonium is an amino-functionalized PEGylated phospholipid. It serves not only as a key component for preparing σ receptor-targeted liposomes (such as anisamide-modified lipids) but also as a starting material for synthesizing click chemistry- and tumor-targeted lipids including DSPE-PEG-DBCO (HY-155788) and DSPE-PEG2000-TCO (HY-170704). DSPE-PEG-Amine, MW 3400 ammonium effectively modulates the ζ potential of nanoparticles, enables complexation with nucleic acids or proteins to protect DNA from nuclease degradation, and supports ligand conjugation on the nanoparticle surface. It is used in studies related to DU-145 tumors, breast cancer, and other relevant research .
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