2. Search Result
Search Result
Results for "

sensor

" in MedChemExpress (MCE) Product Catalog:

97

Inhibitors & Agonists

1

Screening Libraries

30

Fluorescent Dye

9

Biochemical Assay Reagents

6

Peptides

7

Natural
Products

13

Isotope-Labeled Compounds

1

Antibodies

2

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-N0667
    L-Asparagine
    5 Publications Verification

    (-)-Asparagine; Asn; Asparamide

    		 Endogenous Metabolite Apoptosis DNA/RNA Synthesis Inflammation/Immunology
    L-Asparagine is an essential amino acid for leukemic cells and a substrate for L-Asparaginase. L-Asparaginase is a potent anti-leukemic enzyme that promotes asparagine (Asn) and glutamine (Gln) depletion and inhibits protein biosynthesis in lymphoblasts. Removal of L-asparagine from plasma by L-Asparaginase results in inhibition of RNA and DNA synthesis and subsequent apoptosis. L-Asparaginase has cell-killing ability in vitro and in vivo, and selectively inhibits the growth of cancer cells with low asparagine synthetase (AASNS) expression. L-Asparagine can be used as a biomarker and sensor for the study of childhood acute lymphoblastic leukemia .
    L-Asparagine
  • HY-W105135
    2,6-Dichloroquinone-4-chloroimide

    		Biochemical Assay Reagents Others
    2,6-Dichloroquinone-4-chloroimide is a spray reagent for organic compounds. 2,6-Dichloroquinone-4-chloroimide can be used in thin-layer chromatograms and detecting phenol and its derivatives. 2,6-Dichloroquinone-4-chloroimide can be used as an optical sensor for rapid detection of permethrin in treated wood .
    2,6-Dichloroquinone-4-chloroimide
  • HY-D1563
    pH Receptor Probe
    1 Publications Verification

    		 Fluorescent Dye Others
    pH Receptor Probe is a pH-sensitive cyanine derivative and a environmental sensitive fluorophore. pH Receptor Probe has a pH-sensitive maximal absorption at 644 nm and emission at 664 nm. pH Receptor Probe has been used as a pH sensor of lysosomal compartments .
    pH Receptor Probe
  • HY-W074143
    Tris(4,7-diphenyl-1,10-phenanthroline)ruthenium(II) dichloride
    Maximum Cited Publications
    10 Publications Verification

    		 Fluorescent Dye Others
    Tris(4,7-diphenyl-1,10-phenanthroline)ruthenium(II) dichloride ([Ru(dpp)3] 2+) is an electrochemiluminescent (ECL) probe and oxygen-sensitive sensor. Tris(4,7-diphenyl-1,10-phenanthroline)ruthenium(II) dichloride can be used to modify electrode surfaces for the detection of sulfates (S2O8 2-) and oxalates, based on electrochemical reactions that generate excited-state species, releasing photons through irreversible redox reactions. Tris(4,7-diphenyl-1,10-phenanthroline)ruthenium(II) dichloride utilizes the oxygen quenching of fluorescence mechanism, where fluorescence intensity reflects the metabolic rate of living microorganisms or oxygen levels within cells/tumors, allowing for real-time detection. Tris(4,7-diphenyl-1,10-phenanthroline)ruthenium(II) dichloride's main applications include microbial detection, antibacterial activity studies, and tumor microenvironment research .
    Tris(4,7-diphenyl-1,10-phenanthroline)ruthenium(II) dichloride
  • HY-B1571
    Bromophenol blue

    		Environmental Pollutants Fluorescent Dye Others
    Bromophenol blue is an acid phthalein dye, and it is used as a tracking dye for electrophoresis. Bromophenol blue is also used as a pH indicator, with a transition range of pH 3 to 4.6. Bromophenol blue is used as a sensor for the determination of several compounds including ammonia, drugs, proteins and amino acids. The binding of Bromophenol blue to proteins is accompanied by the appearance of a strong absorbance at 610 nm .
    Bromophenol blue
  • HY-101900
    Nile Blue A sulfate

    Nile blue sulfate

    		 Fluorescent Dye Others
    Nile Blue A (Nile blue sulfate) is used to differentiate melanins and lipofuscins. It is also useful for staining fats and preparation of an amperometric glucose sensor .
    Nile Blue A sulfate
  • HY-B1306
    4-Aminohippuric acid
    4 Publications Verification

    p-Aminohippuric acid

    		 Others Neurological Disease Metabolic Disease
    4-Aminohippuric acid (p-Aminohippuric acid) is a coordination ligand for metal ions (such as Cu 2+, Fe 3+, Hg 2+) and a functionalization reagent for nanomaterials. 4-Aminohippuric acid can coordinate with metal ions or modify the surface of materials such as carbon nanotubes and gold nanoparticles through amino and carboxyl groups. 4-Aminohippuric acid can form stable complexes with metal ions or participate in the synthesis of nanomaterials as a reducing agent/stabilizer, enriching metal ions or giving nanoparticles peroxidase-mimicking activity. 4-Aminohippuric acid can be used to construct highly sensitive electrochemical sensors or colorimetric sensors to detect and quantitatively analyze heavy metal ions such as copper, iron, and mercury in environmental water samples and biological samples. 4-Aminohippuric acid may also be a biomarker for attention-deficit/hyperactivity disorder (ADHD) .
    4-Aminohippuric acid
  • HY-W017289
    4,4′-Dipyridyl

    		Drug Intermediate Others
    4,4′-Dipyridyl is a heterocyclic compound. 4,4′-Dipyridyl is utilized as an electronic and photosensitive building block and bidentate ligand in supramolecular chemistry. 4,4′-Dipyridyl can also be used as a drug intermediate in the synthesis of paraquat, a widely used herbicide .
    4,4′-Dipyridyl
  • HY-Y1134
    D-Tartaric acid

    D-(-)-Tartaric acid

    		 Biochemical Assay Reagents Bacterial Infection
    D-Tartaric acid (D-(-)-Tartaric acid) serves as an additive in beverages and other food products. When combined with pyrrole, D-Tartaric acid is used to construct a D-TA/polypyrrole-based bacterial imprinted polymer sensor for the detection of Vibrio parahaemolyticus. D-Tartaric acid enhances the sensitivity of polypyrrole-based bacterial imprinted polymer sensors for detecting Vibrio parahaemolyticus. D-Tartaric acid is applicable to research on Vibrio parahaemolyticus infection .
    D-Tartaric acid
  • HY-N0667S2
    L-Asparagine-15N2 monohydrate
    1 Publications Verification

    (-)-Asparagine-15N2 monohydrate; Asn-15N2 monohydrate; Asparamide-15N2 monohydrate

    		 Isotope-Labeled Compounds Endogenous Metabolite Apoptosis DNA/RNA Synthesis Inflammation/Immunology
    L-Asparagine- 15N2 monohydrate is the 15N-labeled L-Asparagine monohydrate (HY-W017443). L-Asparagine monohydrate is an essential amino acid for leukemic cells and a substrate for L-Asparaginase. L-Asparaginase is a potent anti-leukemic enzyme that promotes asparagine (Asn) and glutamine (Gln) depletion and inhibits protein biosynthesis in lymphoblasts. Removal of L-asparagine from plasma by L-Asparaginase results in inhibition of RNA and DNA synthesis and subsequent apoptosis. L-Asparaginase has cell-killing ability in vitro and in vivo, and selectively inhibits the growth of cancer cells with low asparagine synthetase (AASNS) expression. L-Asparagine monohydrate can be used as a biomarker and sensor for the study of childhood acute lymphoblastic leukemia .
    L-Asparagine-15N2 monohydrate
  • HY-154954
    Ogremorphin
    2 Publications Verification

    OGM; GPR68-IN-1; OGM-8345

    		 GPR68 Ferroptosis Inflammation/Immunology Cancer
    Ogremorphin (OGM) is a G protein coupled sensor GPR68 inhibitor with anti-inflammatory and anti-tumor activities. Ogremorphin can inhibit the migration of human melanoma cells and induce ferroptosis in glioblastoma cells .
    Ogremorphin
  • HY-W017443
    L-Asparagine monohydrate
    5 Publications Verification

    		 Endogenous Metabolite Apoptosis DNA/RNA Synthesis Neurological Disease Metabolic Disease Inflammation/Immunology Cancer
    L-Asparagine monohydrate is an essential amino acid for leukemic cells and a substrate for L-Asparaginase. L-Asparaginase is a potent anti-leukemic enzyme that promotes asparagine (Asn) and glutamine (Gln) depletion and inhibits protein biosynthesis in lymphoblasts. Removal of L-asparagine from plasma by L-Asparaginase results in inhibition of RNA and DNA synthesis and subsequent apoptosis. L-Asparaginase has cell-killing ability in vitro and in vivo, and selectively inhibits the growth of cancer cells with low asparagine synthetase (AASNS) expression. L-Asparagine monohydrate can be used as a biomarker and sensor for the study of childhood acute lymphoblastic leukemia .
    L-Asparagine monohydrate
  • HY-118952A
    PF-06456384 trihydrochloride

    		Sodium Channel Neurological Disease
    PF-06456384 trihydrochloride is an extremely potent and selective Nav1.7 sodium channel blocker (IC50: 0.01 nM for hNaV1.7; 75 nM for rNaV1.7; <0.1 nM for mNaV1.7). PF-06456384 trihydrochloride shows no significant analgesic efficacy in the mouse Formalin pain model .
    PF-06456384 trihydrochloride
  • HY-172445
    Deoxyribonucleic acid sodium salt from salmon testes

    SS-DNA

    		 Biochemical Assay Reagents Others
    Deoxyribonucleic acid sodium salt from salmon testes (ssstDNA) can be used to make anti-adhesion layers (AALs) for passivating gold plasmonic sensor surfaces .
    Deoxyribonucleic acid sodium salt from salmon testes
  • HY-W020249
    Sodium ionophore X

    		Biochemical Assay Reagents Others
    Sodium ionophore X is a neutral ionophore that binds highly selectively to sodium ions (Na +) to form stable complexes. Sodium ionophore X can be used to construct ion-selective chemical sensors (including optical sensors and electrochemical sensors) .
    Sodium ionophore X
  • HY-126774
    DAF-FM
    1 Publications Verification

    		 Fluorescent Dye Others
    DAF-FM is a cell-impermeant diaminofluorescein, which can be used as fluorescent indicator for nitric oxide (NO) with good pH tolerance .
    DAF-FM
  • HY-W089777
    3-Glycidyloxypropyltrimethoxysilane

    GPTMS

    		 Biochemical Assay Reagents Others
    3-Glycidyloxypropyltrimethoxysilane (GPTMS) is a silicon source for the preparation of inorganic-organic hybrid polymers. 3-Glycidyloxypropyltrimethoxysilane can be used to prepare hard coatings of organic polymers, such as contact lens materials in the optical industry, as well as related materials in the fields of electronics, thin films, sensors, nanoimprinting, waveguides, and biology .
    3-Glycidyloxypropyltrimethoxysilane
  • HY-P2726
    Aldolase, Rabbit muscle

    Fructose-diphosphate aldolase

    		 Fructose-1,6-bisphosphate aldolase Endogenous Metabolite Metabolic Disease
    Aldolase, Rabbit muscle (Fructose-diphosphate aldolase) is a glycolytic enzyme and glucose availability sensor. Aldolase, Rabbit muscle catalyzes the reversible carbon-carbon cleavage of fructose-1,6-bisphosphate to produce dihydroxyacetone phosphate and glyceraldehyde 3-phosphate. Aldolase, Rabbit muscle is an essential component for v-ATPase activity. Aldolase, Rabbit muscle participates in processes such as gluconeogenesis, the Calvin cycle and glycolysis .
    Aldolase, Rabbit muscle
  • HY-120972
    Pentafluorobenzenesulfonyl fluorescein

    		Fluorescent Dye Others
    Pentafluorobenzenesulfonyl fluorescein is a H2O2-selective sensor that can be used to detect H2O2 levels in cells. Pentafluorobenzenesulfonyl fluorescein is generally non-fluorescent, but emits fluorescence when its sulfonyl bond undergoes perhydrolysis by H2O2 . Pentafluorobenzenesulfonyl fluorescein undergoes slight cleavage of its sulfonate ester bond by [Cu (phen)2] 2+, and can detect hydrogen peroxide around the ablation sites of fin tissues and keratinocytes in zebrafish larvae .
    Pentafluorobenzenesulfonyl fluorescein
  • HY-D0219
    Thymol blue

    Thymolsulphonephthalein

    		 Fluorescent Dye Others
    Thymol blue is a reversible pH indicator that responds to the pH of the solution through structural changes of protonation and deprotonation. Thymol blue is red (HI - form) under acidic conditions and blue (I 2- form) under alkaline conditions. Quantitative detection is achieved through the absorption peak shift (435 nm/596 nm) of the UV-visible spectrum. Thymol blue selectively responds to pH changes, changing from red to yellow at pH 1.2-2.8 and from yellow to blue at pH 8.0-9.6. Thymol blue can be fixed in a silica gel matrix through sol-gel technology to form a solid-state sensor for in-situ pH measurement in the marine environment and acid-base monitoring in the biomedical field[1][2].
    Thymol blue
  • HY-P10817
    Corza6

    		Proton Pump Reactive Oxygen Species (ROS) Metabolic Disease
    Corza6 is a potent and selective human voltage-gated proton channel (hHv1) peptide inhibitor. Corza6 binds to the external voltage sensor domain (VSD) loop in hHv1 with a Kd of ~1 nM at the natural, hyperpolarized resting membrane potential (RMP) of mammalian cells. Corza6 allows capacitation in sperm and permits sustained reactive oxygen species (ROS) production in white blood cells (WBCs) .
    Corza6
  • HY-121310
    Phthalocyanine

    		MOFs Bacterial Infection Cancer
    Phthalocyanine is a photosensitizer. Phthalocyanine has a light-killing effect on bacterial biofilms, effectively inactivating bacteria. Phthalocyanine can be linked to anticancer drugs to target cancer. Phthalocyanine can also be used to develop chemical sensors for studying microbial infections and tumors .
    Phthalocyanine
  • HY-D1599
    Rhodamine 6G hydrazide

    R6GH

    		 Fluorescent Dye Others
    Rhodamine 6G hydrazide (R6GH) is a fluorescent dye. Rhodamine 6G hydrazide can be used in selective colorimetric and fluorescent sensing .
    Rhodamine 6G hydrazide
  • HY-D2264
    Caffeine orange

    		Fluorescent Dye Others
    Caffeine orange (Compound 1) is an aqueous-phase fluorescence turn-on sensor for caffeine that is highly selective to caffeine. Caffeine orange makes caffeinated coffee appear orange when exposed to 532 nM of green excitation light. Caffeine orange has excellent photophysical properties such as high extinction coefficient, high light stability and narrow emission bandwidth, which can be used in the research of caffeine detection devices .
    Caffeine orange
  • HY-D0156
    ZnAF-1

    		Fluorescent Dye Others
    ZnAF-1, a fluorescein-based zinc sensor containing the N,N-bis(2-pyridylmethyl)ethylenediamine chelating unit, can be used for Zn2+ detection . ZnAF-1 can bind Zn(II) with a 1 : 1 stoichiometry .
    ZnAF-1
  • HY-P10817A
    Corza6 TFA

    		Proton Pump Reactive Oxygen Species (ROS) Metabolic Disease
    Corza6 TFA is a potent and selective human voltage-gated proton channel (hHv1) peptide inhibitor. Corza6 TFA binds to the external voltage sensor domain (VSD) loop in hHv1 with a Kd of ~1 nM at the natural, hyperpolarized resting membrane potential (RMP) of mammalian cells. Corza6 TFA allows capacitation in sperm and permits sustained reactive oxygen species (ROS) production in white blood cells (WBCs) .
    Corza6 TFA
  • HY-D0982
    Zinquin

    		Fluorescent Dye Others
    Zinquin is a cell-impermeant fluorescent sensor and used to observe reactive Zn 2+. λex/λem=368/490 nm.
    Zinquin
  • HY-D2335
    SERTlight

    		Fluorescent Dye Neurological Disease
    SERTlight is a fluorescent agent that can specifically label serotonergic neuronal cell bodies, dendrites, and axonal projections as fluorescent substrates of the serotonin transporter (SERT). SERTlight is orthogonal to various genetically encoded sensors in terms of optics, pharmacology, and operation, enabling multiple imaging. SERTlight allows the use of GRAB5HT sensors to label distal 5HT axonal projections and simultaneously image the release of endogenous 5HT, providing a new multifunctional molecular tool for studying serotonergic systems .
    SERTlight
  • HY-D2775
    Cobalt(II) ions probe 1

    		Fluorescent Dye Others
    Cobalt(II) ions probe 1 (Compound L) is a fluorescent sensor for Co 2+ detecting in biological environments. Cobalt(II) ions probe 1 can selectively bind with Co 2+ in the presence of other metal ions (Ex: 380 nm) .
    Cobalt(II) ions probe 1
  • HY-D1703
    Oxazine 170 perchlorate

    		Fluorescent Dye Others
    Oxazine 170 perchlorate is a laser dye with a wide excitation spectrum range (300−550 nm), which strongly absorbs light with a wavelength greater than 550 nm, and it emits fluorescence with a wavelength of about 645 nm .
    Oxazine 170 perchlorate
  • HY-N0667S5
    L-Asparagine-d3 hydrate
    1 Publications Verification

    		 Isotope-Labeled Compounds Endogenous Metabolite Apoptosis DNA/RNA Synthesis Inflammation/Immunology
    L-Asparagine-d3 hydrate is the deuterium labeled L-Asparagine (HY-N0667). L-Asparagine is an essential amino acid for leukemic cells and a substrate for L-Asparaginase. L-Asparaginase is a potent anti-leukemic enzyme that promotes asparagine (Asn) and glutamine (Gln) depletion and inhibits protein biosynthesis in lymphoblasts. Removal of L-asparagine from plasma by L-Asparaginase results in inhibition of RNA and DNA synthesis and subsequent apoptosis. L-Asparaginase has cell-killing ability in vitro and in vivo, and selectively inhibits the growth of cancer cells with low asparagine synthetase (AASNS) expression. L-Asparagine can be used as a biomarker and sensor for the study of childhood acute lymphoblastic leukemia .
    L-Asparagine-d3 hydrate
  • HY-D1677
    5(6)-Carboxynaphthofluorescein

    		Fluorescent Dye Others
    5(6)-Carboxynaphthofluorescein is a pH-dependent fluorophore. 5(6)-Carboxynaphthofluorescein shows good sensitivity in an alkaline pH range and it can be exploited in the construction of fiber-optic pH sensors. 5(6)-Carboxynaphthofluorescein can be used as a fluorescent pH indicator (Ex/Em=593/668 nm) .
    5(6)-Carboxynaphthofluorescein
  • HY-DY1071
    pH Receptor Probe (solution)

    		Fluorescent Dye Others
    pH Receptor Probe (solution) is a pH-sensitive cyanine derivative and a environmental sensitive fluorophore. pH Receptor Probe has a pH-sensitive maximal absorption at 644 nm and emission at 664 nm. pH Receptor Probe has been used as a pH sensor of lysosomal compartments .
    Solvent and concentration: DMSO: 10 mM
    pH Receptor Probe (solution)
  • HY-155254
    Sodium ionophore VI

    		Biochemical Assay Reagents Others
    Sodium ionophore VI is a sodium ionophore that has been employed for developing cation optical sensors .
    Sodium ionophore VI
  • HY-75200
    N-(Benzyloxycarbonyloxy)succinimide

    		Biochemical Assay Reagents Others
    N-(Benzyloxycarbonyloxy)succinimide is an efficient amino-protecting reagent in organic synthesis, playing an important role in the field of organic synthesis. N-(Benzyloxycarbonyloxy)succinimide is also a neutral ionophore, which significantly improves the performance of erbium ion (Er 3+) sensors and provides a practical tool for the rapid detection of erbium ions in the environment and water quality .
    N-(Benzyloxycarbonyloxy)succinimide
  • HY-138646
    Poly(deoxyadenylic-thymidylic) acid sodium
    4 Publications Verification

    Poly(dA:dT) sodium

    		 Cyclic GMP-AMP Synthase STING Inflammation/Immunology
    Poly(deoxyadenylic-thymidylic) acid (Poly(dA:dT)) sodium is a double-stranded DNA stimulant. Poly(deoxyadenylic-thymidylic) acid sodium is recognized by the intracellular DNA sensor DDX41 and activates the innate immune pathway via the adaptor protein STING, inducing the production of cytokines such as type I interferons. Poly(deoxyadenylic-thymidylic) acid sodium also serves as an in vitro transcription template for free RNA polymerase .
    Poly(deoxyadenylic-thymidylic) acid sodium
  • HY-N0667R
    L-Asparagine (Standard)

    (-)-Asparagine (Standard); Asn (Standard); Asparamide (Standard)

    		 Reference Standards Endogenous Metabolite Apoptosis DNA/RNA Synthesis Inflammation/Immunology
    L-Asparagine (Standard) is the analytical standard of L-Asparagine (HY-N0667). This product is intended for research and analytical applications. L-Asparagine is an essential amino acid for leukemic cells and a substrate for L-Asparaginase. L-Asparaginase is a potent anti-leukemic enzyme that promotes asparagine (Asn) and glutamine (Gln) depletion and inhibits protein biosynthesis in lymphoblasts. Removal of L-asparagine from plasma by L-Asparaginase results in inhibition of RNA and DNA synthesis and subsequent apoptosis. L-Asparaginase has cell-killing ability in vitro and in vivo, and selectively inhibits the growth of cancer cells with low asparagine synthetase (AASNS) expression. L-Asparagine can be used as a biomarker and sensor for the study of childhood acute lymphoblastic leukemia .
    L-Asparagine (Standard)
  • HY-W017443S
    L-Asparagine-13C4,15N2 monohydrate

    		Isotope-Labeled Compounds Endogenous Metabolite Apoptosis DNA/RNA Synthesis Neurological Disease Metabolic Disease Inflammation/Immunology Cancer
    L-Asparagine- 13C4, 15N2 monohydrateis the 13C-labeled and 15N-labeled L-Asparagine monohydrate (HY-W017443). L-Asparagine monohydrate is an essential amino acid for leukemic cells and a substrate for L-Asparaginase. L-Asparaginase is a potent anti-leukemic enzyme that promotes asparagine (Asn) and glutamine (Gln) depletion and inhibits protein biosynthesis in lymphoblasts. Removal of L-asparagine from plasma by L-Asparaginase results in inhibition of RNA and DNA synthesis and subsequent apoptosis. L-Asparaginase has cell-killing ability in vitro and in vivo, and selectively inhibits the growth of cancer cells with low asparagine synthetase (AASNS) expression. L-Asparagine monohydrate can be used as a biomarker and sensor for the study of childhood acute lymphoblastic leukemia .
    L-Asparagine-13C4,15N2 monohydrate
  • HY-P1073
    ProTx-I

    		Calcium Channel Potassium Channel Sodium Channel TRP Channel Neurological Disease Cancer
    ProTx-I is a toxin derived from Thrixopelma pruriens and a peptide inhibitor targeting TTX-resistant sodium channels. ProTx-I interacts with voltage sensors of multiple domains such as NaV1.7, reduces neuronal excitability through allosteric modulation of channel gating and alteration of voltage dependence. The IC50 values of ProTx-I against human NaV1.7, NaV1.2, NaV1.6, and NaV1.5 are 95 nM, 104 nM, 21 nM, and 358 nM, respectively; ProTx-I also potently inhibits Ba 2+ currents of hCav3.1, while its inhibitory potency against hCav3.2 is approximately 160-fold lower. ProTx-I is applicable to the research of chronic pain .
    ProTx-I
  • HY-115658
    VU0420373

    		Bacterial Infection Metabolic Disease
    VU0420373 is a potent heme sensor system (HssRS) activator with an EC50 of 10.7 μM and a pEC50 of 4.97. VU0420373 induces heme biosynthesis, and is toxic to fermenting S. aureus .
    VU0420373
  • HY-117005
    C450-0730

    		Bacterial Infection
    C450-0730 is an antagonist targeting the AHL membrane-bound sensor kinase and is an antagonist of the nine-transmembrane protein LuxN of Vibrio harveyi . C450-0730 competitively binds to the LuxN AI-1 binding site and specifically antagonizes the LuxN/AI-1 quorum sensing signal in Vibrio harveyi. The inhibitory activity of C450-0730 against LuxN I209F was not significant .
    C450-0730
  • HY-160052
    IL-6 aptamer sodium

    		Interleukin Related Inflammation/Immunology Cancer
    IL-6 aptamer sodium is an aptamer that specifically binds to IL-6, and can serve as a biological recognition receptor for high-sensitivity detection. IL-6 aptamer sodium enables label-free specific detection through changes in electrical signals of carbon nanotube microarrays or alterations in capacitive impedance on the surface of gold sensors. IL-6 aptamer sodium still maintains high selectivity even below the gray zone threshold for cancer diagnosis, and shows no significant non-specific binding to bovine serum albumin. IL-6 aptamer sodium can form an ordered self-assembled monolayer with 6-mercapto-1-hexanol on gold surfaces, making it suitable for reagent-free capacitive impedance biosensing platforms. IL-6 aptamer sodium is widely used in research related to fields such as cancer, inflammatory diseases, myeloma, liver cancer and glioma .
    IL-6 aptamer sodium
  • HY-123414
    GX-936

    PF-05196233

    		 Sodium Channel Neurological Disease
    GX-936 (PF-05196233), a potent and Nav1.7-subtype selective inhibitor, binds to the activated state of voltage-sensor domain IV (VSD4) .
    GX-936
  • HY-131007
    FFN270 hydrochloride

    		Adrenergic Receptor Metabolic Disease
    FFN270 hydrochloride, a fluorescent tracer of norepinephrine, is a fluorescent substrate of the norepinephrine and vesicular monoamine transporters. FFN270 hydrochloride exhibits two resolved absorption/excitation maxima depending on solvent pH (FFN270 ex: 320 nm or 365 nm, em: 475 nm) and can function as ratiometric fluorescent pH-sensors .
    FFN270 hydrochloride
  • HY-B1306R
    4-Aminohippuric acid (Standard)

    p-Aminohippuric acid (Standard)

    		 Reference Standards Biochemical Assay Reagents Neurological Disease Metabolic Disease
    4-Aminohippuric acid (p-Aminohippuric acid) (Standard) is the analytical standard of 4-Aminohippuric acid (HY-B1306). This product is intended for research and analytical applications. 4-Aminohippuric acid (p-Aminohippuric acid) is a coordination ligand for metal ions (such as Cu 2+, Fe 3+, Hg 2+) and a functionalization reagent for nanomaterials. 4-Aminohippuric acid can coordinate with metal ions or modify the surface of materials such as carbon nanotubes and gold nanoparticles through amino and carboxyl groups. 4-Aminohippuric acid can form stable complexes with metal ions or participate in the synthesis of nanomaterials as a reducing agent/stabilizer, enriching metal ions or giving nanoparticles peroxidase-mimicking activity. 4-Aminohippuric acid can be used to construct highly sensitive electrochemical sensors or colorimetric sensors to detect and quantitatively analyze heavy metal ions such as copper, iron, and mercury in environmental water samples and biological samples. 4-Aminohippuric acid may also be a biomarker for attention-deficit/hyperactivity disorder (ADHD) .
    4-Aminohippuric acid (Standard)
  • HY-D0219A
    Thymol Blue sodium

    		Fluorescent Dye Others
    Thymol Blue sodium is an acid-base indicator used to indicate changes in pH. Thymol Blue sodium fades from red to yellow at pH 1.2 to 2.8 and from yellow to blue at pH 8.0 to 9.6. Quantitative detection is achieved through the absorption peak shift (435 nm/596 nm) of the UV-visible spectrum. Thymol blue sodium can be fixed in a silica gel matrix through sol-gel technology to form a solid-state sensor for in-situ pH measurement in the marine environment and acid-base monitoring in the biomedical field .
    Thymol Blue sodium
  • HY-W116336B
    Zinc oxide, 99.99% metals basis

    		Biochemical Assay Reagents Fungal Bacterial Infection Cancer
    Zinc oxide, 99.99% metals basis is a versatile wide-bandgap semiconductor with superior comprehensive properties. Zinc oxide, 99.99% metals basis serves as raw material for Schottky diodes, functional nanostructures, sensors, energy harvesters and photocatalysts for hydrogen production. Zinc oxide, 99.99% metals basis acts as a non-toxic antibacterial agent and selective cytotoxin against multiple bacteria, fungi and spores. Zinc oxide, 99.99% metals basis induces cancer cell death. Zinc oxide, 99.99% metals basis is applicable to drug delivery, biosensing, bioimaging and researches on cancer, microbial infections and skin diseases .
    Zinc oxide, 99.99% metals basis
  • HY-N0667S3
    L-Asparagine-13C4 monohydrate

    (-)-Asparagine-13C4 monohydrate; Asn-13C4 monohydrate; Asparamide-13C4 monohydrate

    		 Isotope-Labeled Compounds Endogenous Metabolite Apoptosis DNA/RNA Synthesis Inflammation/Immunology
    L-Asparagine- 13C4 monohydrate is the 13C-labeled L-Asparagine monohydrate (HY-W017443). L-Asparagine monohydrate is an essential amino acid for leukemic cells and a substrate for L-Asparaginase. L-Asparaginase is a potent anti-leukemic enzyme that promotes asparagine (Asn) and glutamine (Gln) depletion and inhibits protein biosynthesis in lymphoblasts. Removal of L-asparagine from plasma by L-Asparaginase results in inhibition of RNA and DNA synthesis and subsequent apoptosis. L-Asparaginase has cell-killing ability in vitro and in vivo, and selectively inhibits the growth of cancer cells with low asparagine synthetase (AASNS) expression. L-Asparagine monohydrate can be used as a biomarker and sensor for the study of childhood acute lymphoblastic leukemia .
    L-Asparagine-13C4 monohydrate
  • HY-P5183
    Hm1a

    		Sodium Channel Neurological Disease
    Hm1a is a venom peptide and a selective hNaV1.1 activator with an EC50 of 7.5 nM. Hm1a enhances hNaV1.1 and hNaV1.3 channel currents via delayed inactivation. Hm1a restores action potential firing in Dravet syndrome GABAergic inhibitory interneurons, reduces interictal epileptiform discharges and whole-brain hyperexcitability, lowers seizure frequency, and rescues premature death in Dravet syndrome mice. Hm1a can be used for the research of neurological disease, such as Dravet syndrome .
    Hm1a
  • HY-W110905
    Naphthol green B

    		Environmental Pollutants Fluorescent Dye Others
    Naphthol green B is an iron-complex dye. Naphthol green B can be used in wool dyeing, silk dyeing and polyamide dyeing. Naphthol green B can be used to fabricate electrochemical sensor for the detection of H2O2 .
    Naphthol green B

Inquiry Online

Your information is safe with us. * Required Fields.

Salutation

  

Country or Region *

Applicant Name *

 

Organization Name *

Department *

     

Email Address *

 

Product Name *

Cat. No.

  

Requested quantity *

Phone Number *

     

Remarks

Inquiry Online

Inquiry Information

Product Name:
Cat. No.:
Quantity:
MCE Japan Authorized Agent: