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Arctigenin

(Synonyms: (-)-Arctigenin)
17 Cited Publications
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Based on 17 publication(s) in Google Scholar

Arctigenin ((-)-Arctigenin), a biologically active lignan, can be used as an antitumor agent. Arctigenin exhibits potent antioxidant, anti-inflammatory and antiviral (influenza A virus) activities. Arctigenin can be used for the research of metabolic disorders, and central nervous system dysfunctions.

For research use only. We do not sell to patients.

  • Purity: 99.63%
  • CAS No.: 7770-78-7
  • Formula: C21H24O6
  • Molecular Weight:372.41
  • Storage:
    Powder   -20°C, 3 years ; In solvent   -80°C, 1 year , -20°C, 6 months
  • Arctigenin Chemical Structure
    Arctigenin Chemical Structure
  • Experimental Validation Results for Arctigenin
  • Experimental Validation Results for Arctigenin
  • Experimental Validation Results for Arctigenin
  • Experimental Validation Results for Arctigenin
  • Experimental Validation Results for Arctigenin
CAS No.: 7770-78-7
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Find Your Local Distributor Your local distributor: Hycultec GmbHHycultec
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WBCell Proliferation/Viability AssayCell Migration/Invasion AssayIn Vivo Efficacy StudyRT-PCR
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  • Cell Proliferation/Viability Assay
  • Cell Migration/Invasion Assay
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  • Arctigenin Chemical Structure
    Arctigenin Chemical Structure
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    Arctigenin purchased from MedChemExpress. Usage Cited in: Pharmacol Res. 2020 May;155:104721. [Abstract]

    Customer Validation
     The Western blotting results show that incubating LA795 cells with 100 μM Arctigenin (24 h) led to a decrease in phospho-MEK1/2, phospho-ERK1/2 and cyclin D1 expression (n = 3).

  • 1/16

    Arctigenin purchased from MedChemExpress. Usage Cited in: Pharmacol Res. 2020 May;155:104721. [Abstract]

    Customer Validation
     Arctigenin (10-200 μM; 24 h) inhibited LA795 cell proliferation by inhibiting TMEM16A. (A), (B), (C) Inhibitory effect of arctigenin to the proliferation of LA795, HeLa and HEK293 cells with different concentrations (n = 8; ** means the P value was less than 0.01 compared with 0 μM group). (D) Inhibitory effect of NC shRNA, TMEM16A shRNA and shRNA added with 200 μM arctigenin to the proliferation of LA795 cells (n = 8; ** means the P value was less than 0.01 compared with control group).

  • 1/16

    Arctigenin purchased from MedChemExpress. Usage Cited in: Pharmacol Res. 2020 May;155:104721. [Abstract]

    Customer Validation
     Migration of LA795 cells in the presence of 0, 10, 20, 50, 100, and 200 μM Arctigenin assessed by wound healing assay.

  • 1/16

    Arctigenin purchased from MedChemExpress. Usage Cited in: Pharmacol Res. 2020 May;155:104721. [Abstract]

    Customer Validation
     The tumor volume growth curve in different groups (n = 6). Arctigenin (14.37 mg/kg; s.c.; once every two days for a total of 9 doses) inhibited the growth of lung adenocarcinomas in xenograft model mice.

  • 1/16

    Arctigenin purchased from MedChemExpress. Usage Cited in: Life Sci. 2020 Sep 1;256:117983. [Abstract]

    Customer Validation
     The indicated cell lines are treated with 5 μM Arc (Arctigenin) for 10 h and then harvested for extraction of total cellular RNA and subsequent qRT-PCR.

  • Arctigenin