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XJTU-L453

XJTU-L453 is a PI3Kα inhibitor with an IC50 value of 0.4 nM. XJTU-L453 can inhibit the proliferation of breast cancer cell lines T47D and MCF7, with IC50 values of 0.2 μM and 0.5 μM, respectively. XJTU-L453 can inhibit the PI3K pathway, induce cell cycle arrest, and trigger cell apoptosis (apoptosis). XJTU-L453 also has antitumor activity in MCF7 xenograft mice.

For research use only. We do not sell to patients.

  • CAS No.: 3008290-92-1
  • Formula: C22H22N4O3
  • Molecular Weight:390.44
  • Storage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • XJTU-L453 Chemical Structure
    XJTU-L453 Chemical Structure
CAS No.: 3008290-92-1
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To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
Find Your Local Distributor Your local distributor: Hycultec GmbHHycultec
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All PI3K Isoforms

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  • XJTU-L453 Chemical Structure
    XJTU-L453 Chemical Structure
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  • XJTU-L453