λ-Cyhalothrin
Based on 4 publication(s) in Google Scholar
λ-Cyhalothrin is a high efficiency, broad-spectrum type II synthetic pyrethroid insecticide containing α-cyano group. λ-Cyhalothrin is used to control a wide range of pests in a variety of applications. λ-Cyhalothrin is a neurotoxin that targets sodium channels in the membranes of neurons in the central nervous system.
For research use only. We do not sell to patients.
- Purity: 99.86%
- CAS No.: 91465-08-6
- Formula: C23H19ClF3NO3
- Molecular Weight:449.85
-
Storage:
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
-
Solvent & Solubility
- Purity & Documentation
- References
-
Help & FAQs
-
Anti-Infection Compound Library
HY-L002
-
Membrane Transporter/Ion Channel Compound Library
HY-L011
-
Anti-Cancer Compound Library
HY-L025
-
Neuroprotective Compound Library
HY-L070
-
Antiparasitic Compound library
HY-L082
-
Sodium Channel Blocker Library
HY-L118
-
Membrane Protein-targeted Compound Library
HY-L149
-
Membrane Receptor-targeted Compound Library
HY-L150
-
Mitochondrial Toxicity Compound Library
HY-L155
-
Ion Channel Compound Library
HY-L166
-
Multi-Target Compound Library
HY-L176
-
Bioactive Compound Library Max
HY-L181
-
MCE Bioactive Compound Library
HY-L001V
-
Bioactive Compound Library
HY-L001
-
Pesticide Compound Library
HY-L183
-
High-Throughput Bioactive Compound Library
HY-L205
-
Biotoxin Library
HY-L220
-
Environmental Pollutant Compound Library
HY-L247
Publications Citing Use of MedChemExpress (MCE) λ-Cyhalothrin
MoreAll Parasite Isoforms
More
Biological Activity
The mechanism of λ-Cyhalothrin toxicity produces delay in sodium channel inactivation, which leads to persistent depolarization of the nerve membrane. λ-Cyhalothrin produces membrane depolarization, calcium ion infl ux, and neurotransmitter release from rat brain synaptosomes[1].
λ-Cyhalothrin possesses estrogenic properties and has an ability to function as a xenoestrogen promoting human breast carcinoma cell proliferation in vitro[1].
λ-Cyhalothrin has found multiple uses in pest (fleas, cockroaches, flies, and ants) control[1].
λ-Cyhalothrin is highly effective against the malaria transmitting species of Anopheles[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
-
CAS No. 91465-08-6
-
Appearance Solid
-
Molecular Weight 449.85
-
Formula C23H19ClF3NO3
-
Color White to off-white
-
SMILES
O=C([C@@H]1C(C)(C)[C@@H]1/C=C(Cl)/C(F)(F)F)O[C@@H](C#N)C2=CC=CC(OC3=CC=CC=C3)=C2
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Publications (4)
-
Journal Impact Factor
-
Most Recent
-
Environ Pollut
Effects of λ-cyhalothrin on the behavior and physiology of Leschenault's rousette bat (Rousettus leschenaultii). [Abstract]2025 May 9:126417. PMID: 40349820 -
Environ Pollut
Foliar application of lambda-cyhalothrin modulates root exudate profile and the rhizosphere bacteria community of dioecious Populus cathayana. [Abstract]2022 Nov 15:313:120123. PMID: 36087893 -
Chem Biol Interact
New insights into Lambda-cyhalothrin-induced lipid metabolism disorder in liver: Crosstalk between oxidative stress and PPARα signaling pathway. [Abstract]2026 Jan 25:424:111872. PMID: 41386472 -
Solvent & Solubility
DMSO : 33.33 mg/mL (74.09 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Select the appropriate dissolution method based on your experimental animal and administration route.
- For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
- To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for In Vivo experiments, it is recommended to prepare freshly and use it on the same day.
- The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.
Please enter the basic information of animal experiments:
-
-
-
-
Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Please enter your animal formula composition:
-
%DMSO +
Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.
-
%+
-
+%Tween-80 + +
-
%Saline +
The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).
Working solution concentration: 0.22 mg/mL
Method for preparing stock solution: mg drug dissolved in μL DMSO. Stock solution concentration: mg/mL. * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
1. Take μL DMSO stock solution;
2. Add μL .
μL , mix evenly;
3. Then add μL Tween 80, mix evenly;
4. Then add μL
Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.
Purity & Documentation
-
Data Sheet (278 KB)
-
SDS (624 KB)
- English - EN (624 KB)
- Français - FR (624 KB)
- Deutsch - DE (624 KB)
- Norwegian - NO (624 KB)
- Español - ES (624 KB)
- Swedish - SV (624 KB)
- Italian - IT (624 KB)
- Korean - KR (624 KB)
- Portuguese - PT (624 KB)
-
Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.2230 mL | 11.1148 mL | 22.2296 mL | 55.5741 mL |
| 5 mM | 0.4446 mL | 2.2230 mL | 4.4459 mL | 11.1148 mL | |
| 10 mM | 0.2223 mL | 1.1115 mL | 2.2230 mL | 5.5574 mL | |
| 15 mM | 0.1482 mL | 0.7410 mL | 1.4820 mL | 3.7049 mL | |
| 20 mM | 0.1111 mL | 0.5557 mL | 1.1115 mL | 2.7787 mL | |
| 25 mM | 0.0889 mL | 0.4446 mL | 0.8892 mL | 2.2230 mL | |
| 30 mM | 0.0741 mL | 0.3705 mL | 0.7410 mL | 1.8525 mL | |
| 40 mM | 0.0556 mL | 0.2779 mL | 0.5557 mL | 1.3894 mL | |
| 50 mM | 0.0445 mL | 0.2223 mL | 0.4446 mL | 1.1115 mL | |
| 60 mM | 0.0370 mL | 0.1852 mL | 0.3705 mL | 0.9262 mL |
λ-Cyhalothrin Related Classifications
HY-B0836 Related Classifications
Powered by Bioz