1. Epigenetics
  2. Histone Methyltransferase
  3. SGC3027


Cat. No.: HY-112445 Purity: 98.52%
Handling Instructions

SGC3027 is a histone methyltransferase inhibitor. SGC3027 is the first potent, selective and cell active chemical probe for PRMT7.

For research use only. We do not sell to patients.

SGC3027 Chemical Structure

SGC3027 Chemical Structure

Size Price Stock Quantity
1 mg USD 170 In-stock
Estimated Time of Arrival: December 31
5 mg USD 600 In-stock
Estimated Time of Arrival: December 31
10 mg   Get quote  
50 mg   Get quote  

* Please select Quantity before adding items.

Customer Review

Based on 1 publication(s) in Google Scholar

Top Publications Citing Use of Products
  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review


SGC3027 is a histone methyltransferase inhibitor[1]. SGC3027 is the first potent, selective and cell active chemical probe for PRMT7[2].

IC50 & Target


In Vitro

SGC3027 is a pro-drug of SGC8158 which releases the active component upon reduction in the cell by reductases. In cellular assays using C2C12 cells, SGC3027 inhibits the methylation of HSP70 with IC50=1.3 μM[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight





ClC1=CC=C(C2=CC(CN(C(CC(C)(C)C3=C(C)C(C(C)=C(C)C3=O)=O)=O)CCCCSC[[email protected]@H]4[[email protected]@H](O)[[email protected]@H](O)[[email protected]](N5C(N=CN=C6N)=C6N=C5)O4)=CC=C2)C=C1


Room temperature in continental US; may vary elsewhere.

Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 250 mg/mL (317.51 mM; Need ultrasonic)

Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.2701 mL 6.3503 mL 12.7005 mL
5 mM 0.2540 mL 1.2701 mL 2.5401 mL
10 mM 0.1270 mL 0.6350 mL 1.2701 mL
*Please refer to the solubility information to select the appropriate solvent.

Purity: 98.52%

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2


SGC3027SGC 3027SGC-3027Histone MethyltransferaseInhibitorinhibitorinhibit

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