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Bacterial Related Products (8891)
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Antibodies (14)
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Related Compound Screening Libraries (1)
- Efloxate (Standard)
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- NDM-1-IN-9
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YM 133
0 ImagesCat. No.: HY-106026CAS No.: 103360-00-5Synonyms: IMC-XVYM 133 (IMC-XV) is a semisynthetic macrolide antibiotic with potent bactericidal activity. YM 133 shows activity against Erythromycin (HY-B0220)-, Josamycin (HY-B1920)-, and rokitamycin-resistant (MIC ≥ 100 μg/mL) strains of staphylococci, streptococci, Bacteroides spp., and Clostridium spp. YM 133 exhibits excellent activity against macrolide-resistant strains and against anaerobes. YM 133 can be used for antibacterial research. -
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LasB-IN-1
0 ImagesCat. No.: HY-163030LasB-IN-1 (compound 5f) is a potent and orally active inhibitor of LasB (IC50 = 8.7 μM). LasB-IN-1 effectively attenuates elastase production and biofilm formation by P. aeruginosa while alleviating the inflammatory response through downregulating MAPK and NF-κB pathways. LasB-IN-1 is potential to be a novel anti-infective candidate against drug-resistant infections. -
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Kibdelin D
0 ImagesCat. No.: HY-N14710CAS No.: 105997-86-2Kibdelin D is resistant to Gram-positive bacteria and has similar effects against Staphylococcus aureus (including methicillin-resistant strains) as Vancomycin (HY-B0671). -
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Myramistin (Standard)
0 ImagesCat. No.: HY-103658RCAS No.: 15809-19-5Synonyms: Miramistin (Standard)Myramistin (Miramistin) (Standard) is the analytical standard of Myramistin (HY-103658). This product is intended for research and analytical applications. Myramistin is a cationic surfactant and disinfectant preservative. Myramistin exhibits high bactericidal activity against Staphylococcus aureus and Escherichia coli, shows lower activity against yeasts and fungi, and is active against HIV, measles virus, mumps virus, as well as influenza viruses of the H3N2 and H5N1 subtypes. Myramistin adsorbs to the negatively charged microbial cell membrane, leading to increased membrane permeability and disruption of membrane integrity, which ultimately results in leakage of intracellular contents, enzyme inactivation, and the death of bacteria/fungi/enveloped viruses. -
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MC-02479
0 ImagesCat. No.: HY-19289CAS No.: 189448-23-5Synonyms: RWJ 54428MC-02479 is a novel cephalosporin. RWJ-54428 has good activity against most of the organisms tested, including methicillin-resistant staphylococci, E. faecalis, and penicillin-resistant pneumococci, and has moderate activity against E. faecium. -
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Arylomycin B1
0 ImagesCat. No.: HY-N13972CAS No.: 459844-24-7Arylomycin B1 is a lipohexapeptide antibiotic against Gram-positive bacteria. -
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Hederacoside C (Standard)
0 ImagesSynonyms: Kalopanaxsaponin B (Standard)Hederacoside C (Standard) is the analytical standard of Hederacoside C. This product is intended for research and analytical applications. Hederacoside C (Kalopanaxsaponin B) is an ingredient that can be obtained mainly from ivy leaves. Hederacoside C mediates inflammation by inhibiting activation of MAPK/NF-κB and its downstream signaling pathway. Hederacoside C has anti-inflammatory and antibacterial activity. -
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T-1228
0 ImagesCat. No.: HY-179396CAS No.: 1884551-35-2T-1228 is a highly selective LpxC inhibitor. T-1228 can effectively block the synthesis of LPS (HY-D1056), causing defects in the bacterial outer membrane structure, increasing membrane permeability, and ultimately leading to bacterial cell death. T-1228 can be used for the study of Gram-negative bacterial infections. -
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Eltrombopag (Standard)
0 ImagesSynonyms: SB-497115 (Standard)Eltrombopag (Standard) is the analytical standard of Eltrombopag. This product is intended for research and analytical applications. Eltrombopag (SB-497115) is an orally active thrombopoietin receptor nonpeptide agonist. Eltrombopag owns thrombopoietic activity, and has been used to research low blood platelet counts with chronic immune thrombocytopenia. Eltrombopag can be used for the research of cardiovascular. Eltrombopag also has highly inhibitory effects against multidrug resistant Staphylococcus aureus. Eltrombopag can induce apoptosis in hepatocellular carcinomab (HCC) as well. -
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Eilatin
0 ImagesCat. No.: HY-183242CAS No.: 120154-96-3Eilatin is a seven-ring pyridoacridine marine alkaloid with anticancer, antibacterial, and antiparasitic activities. Eilatin acts as a DNA intercalator with selectivity for electron-deficient polycyclic purines; it can chelate Ni2+ ions and cleave DNA via hydroxyl radical generation. Eilatin induces the SOS response in bacteria, inhibits cancer cell proliferation, and induces cancer cell differentiation and reversion of transformation. The IC50 of Eilatin against Trypanosoma brucei brucei is 1.33 μM. Eilatin can be used in research related to colon tumors, neuroblastoma, chronic myeloid leukemia, acute myeloid leukemia, and trypanosome infections. -
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cOB1 phermone
0 ImagesCat. No.: HY-P5554CAS No.: 163193-68-8cOB1 phermone, a bacterial sex pheromone, effectively inhibits multidrug-resistant Enterococcus faecalis V583. -
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Thunberginol C
0 ImagesCat. No.: HY-N1151CAS No.: 147517-06-4Thunberginol C is an orally active, selective, and non-competitive inhibitor of AChE and BChE, with IC50 values of 41.96 and 42.36 μM, respectively. Thunberginol C exerts cytoprotective, pro-collagen type I restorative, MMP-1 inhibitory, hyaluronic acid restorative, anti-photoaging effects in skin cells. Thunberginol C exerts neuroprotective, anxiolytic, TNF-α inhibitory, neuroinflammation inhibitory, and oxidative stress inhibitory effects. Thunberginol C can be used for the research of Alzheimer’s disease, UVB-induced skin photoaging, allergic reactions, oral bacterial infections, and stress-induced anxiety. -
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CL-55
0 ImagesCat. No.: HY-120450CAS No.: 1370706-59-4CL-55 is an inhibitor for type three secretion system of Chlamydia trachomatis, that blocks the effector molecules delivery of bacteria into host cells. CL-55 ameliorates the C. trachomatis infection and inflammation in mice. -
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DprE1-IN-2 (Standard)
0 ImagesCat. No.: HY-100531RCAS No.: 1615713-87-5DprE1-IN-2 (Standard) is the analytical standard of DprE1-IN-2 (HY-100531). This product is intended for research and analytical applications. DprE1-IN-2 (compound 18) is a potent DprE1 inhibitor with an IC50 of 28 nM. DprE1-IN-2 has antituberculosis effect. -
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Cefalonium-d4 hydrate
0 ImagesCat. No.: HY-B1252ASCefalonium-d4 hydrate is the deuterated-labeled Cefalonium hydrate (HY-B1252A). Cefalonium hydrate is a first-generation cephalosporin bactericidal antimicrobial agent. Cefalonium hydrate can be used in studies related to bovine mastitis, Staphylococcus aureus-induced mastitis and intramammary infections. -
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Kocurin
0 ImagesCat. No.: HY-W748000CAS No.: 1374772-61-8Synonyms: PM181104; BaringolinKocurin (PM181104) is a thiazolyl cyclic-peptide antibiotic. Kocurin inhibits bacterial growth by impeding bacterial protein biosynthesis during the translation phase. Kocurin has strong inhibitory activity against Gram-positive bacteria, but no activity against fungi and Gram-negative bacteria. -
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Ibezapolstat hydrochloride
0 ImagesCat. No.: HY-128357ACAS No.: 1275582-98-3Synonyms: ACX-362E hydrochloride; GLS-362E hydrochlorideIbezapolstat hydrochloride is a first-in-class, orally active DNA polymerase IIIC (pol IIIC) inhibitor, with a Ki of 0.325 μM for the DNA pol IIIC from C. difficile. Ibezapolstat hydrochloride is developed for the research of C. difficile infection(CDI). -
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Rosuvastatin Sodium (Standard)
0 ImagesSynonyms: ZD 4522 Sodium (Standard); X-Plended Sodium (Standard); Crestor Sodium (Standard)Rosuvastatin Sodium (Standard) (ZD 4522 Sodium (Standard)) is the analytical standard of Rosuvastatin Sodium (HY-17504B). This product is intended for research and analytical applications. Rosuvastatin Sodium is a competitive HMG-CoA reductase (HMGCR) inhibitor, with an IC50 of 11 nM. Rosuvastatin Sodium potently blocks hERG current with an IC50 of 195 nM. Rosuvastatin Sodium reduces the expression of the mature hERG and the interaction of heat shock protein 70 (Hsp70) with the hERG protein. Rosuvastatin Sodium effectively lowers low-density lipoprotein (LDL) cholesterol, triglycerides, and C-reactive protein levels. -
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