2. Signaling Pathways
  3. Immunology/Inflammation
  4. Interleukin Related
  5. IL-5 Isoform
  6. IL-5 Inhibitor

IL-5 Inhibitor

IL-5 Inhibitors (8):

Cat. No. Product Name Effect Purity
  • HY-14644
    Apilimod
    		Inhibitor 99.55%
    Apilimod (STA 5326) is a potent IL-12/IL-23 inhibitor, and strongly inhibits IL-12 with IC50s of 1 nM and 2 nM, in IFN-γ/SAC-stimulated human PBMCs and SAC-treated monkey PBMCs, respectively.
  • HY-14644A
    Apilimod mesylate
    		Inhibitor 99.83%
    Apilimod (STA 5326) mesylate is a potent IL-12/IL-23 inhibitor, and strongly inhibits IL-12 with IC50s of 1 nM and 2 nM, in IFN-γ/SAC-stimulated human PBMCs and SAC-treated monkey PBMCs, respectively.
  • HY-19969
    YM-90709
    		Inhibitor 99.77%
    YM-90709 is a novel IL-5 inhibitor which selectively blocks the binding of IL-5 to the IL-5 receptor (IL-5R).
  • HY-17002
    Suplatast (Tosilate)
    		Inhibitor 98.33%
    Suplatast Tosilate (IPD 1151T) is an orally active Th2 cytokine inhibitor which can inhibit both IL-4 and IL-5 production from Th2 cells and suppress IgE synthesis.
  • HY-P9923
    Benralizumab
    		Inhibitor 99.1%
    Benralizumab (MEDI-563) is an interleukin-5 receptor α (IL-5Rα)-directed cytolytic monoclonal antibody that induces direct, rapid and nearly complete depletion of eosinophils via enhanced antibody-dependent cell-mediated cytotoxicity.
  • HY-P1111
    Lyn peptide inhibitor
    		Inhibitor
    Lyn peptide inhibitor is a potent and cell-permeable inhibitor of Lyn-coupled IL-5 receptor signaling pathway, while keeping other signals intact.
  • HY-N8309
    Luteolin-4'-O-glucoside
    		Inhibitor 99.05%
    Luteolin-4'-O-glucoside is an IL-5 inhibitor with an IC50 of 3.7 μM.
  • HY-P1111A
    Lyn peptide inhibitor TFA
    		Inhibitor
    Lyn peptide inhibitor TFA is a potent and cell-permeable inhibitor of Lyn-coupled IL-5 receptor signaling pathway, while keeping other signals intact.