- Signalwege
- Membrane Transporter/Ion Channel
- Potassium Channel
Potassium Channel
KcsA
All Product Categories
-
Potassium Channel Inhibitors
(693)
View all products
-
Potassium Channel Agonists
(31)
View all products
-
Potassium Channel Antagonists
(39)
View all products
-
Potassium Channel Activators
(242)
View all products
-
Potassium Channel Modulators
(44)
View all products
-
Potassium Channel Chemical
(1)
View all products
-
Potassium Channel Controls
(11)
View all products
-
Potassium Channel Verwandte Produkte (1155)
Verwandte Produkte (1155)
-
Antibodies (6)
-
Related Compound Screening Libraries (1)
- GsAF-I
-
loading...Please select quantityAngebot einholen
August 31
-
Please select quantity
August 31
Angebot einholen
loading... -
-
Glibenclamide potassium
0 ImagesArt. -Nr.: HY-15206ACAS. Nr.: 52169-36-5Synonyms: Glyburide potassiumGlibenclamide (Glyburide) potassium is a potassium salt of Glibenclamide (HY-15206). Glibenclamid potassium exists in anhydrous and hydrate forms, with higher solubility compared to pure Glibenclamide. -
loading...Please select quantityAngebot einholen
August 31
-
Please select quantity
August 31
Angebot einholen
loading... -
-
Kv7.2 modulator 1
0 ImagesArt. -Nr.: HY-161624CAS. Nr.: 3034884-49-3Kv7.2 modulator 1 (compound 10) is a Kv7.2 channel modulator and can be used for study of epilepsy. -
loading...Please select quantityAngebot einholen
August 31
-
Please select quantity
August 31
Angebot einholen
loading... -
-
(S)-(+)-Modafinic acid-d5
0 ImagesArt. -Nr.: HY-78327AS(S)-(+)-Modafinic acid-d5 is deuterium labeled (S)-(+)-Modafinic acid. -
loading...Please select quantityAngebot einholen
August 31
-
Please select quantity
August 31
Angebot einholen
loading... -
-
Trimebutine-d5 fumarate
0 ImagesArt. -Nr.: HY-B0380S1CAS. Nr.: 2747915-18-8Trimebutine-d5 fumarate is deuterium labeled Trimebutine fumarate. Trimebutine fumarate is a multi-target inhibitor and opioid receptor agonist with antimuscarinic activity. Trimebutine fumarate inhibits L-type Ca2+ channels and large-conductance calcium-activated potassium channels (BKCa channels), thereby inhibiting extracellular calcium influx and potassium ion efflux. Trimebutine fumarate also targets Toll-like receptors, inhibits Toll-like receptor 2/4/7/8/9 signals, and inhibits LPS-induced IRAK1 activation, as well as ERK1/2, JNK and NF-κB activation, thereby exerting anti-inflammatory effects. Trimebutine fumarate also induces tumor cell apoptosis by inhibiting the AKT/ERK pathway. Trimebutine fumarate also inhibits excessive contraction of smooth muscle and can be used in the study of gastrointestinal disorders such as irritable bowel syndrome (IBS). -
loading...Please select quantityAngebot einholen
August 31
-
Please select quantity
August 31
Angebot einholen
loading... -
-
ShK-Dap22
0 ImagesArt. -Nr.: HY-P1274CAS. Nr.: 220384-25-8ShK-Dap22 is a potent Kv1.3-specific immunosuppressive Polypeptide. ShK-Dap22 is a selective Kv1.3 channel blocker with IC50s of 23 pM, 1.8 nM, 10.5 nM, 37 nM, and 39 nM for mKv1.3, mKv1.1, hKv1.6, mKv1.4, and rKv1.2 channels, respectively. -
loading...Please select quantityAngebot einholen
August 31
-
Please select quantity
August 31
Angebot einholen
loading... -
-
Tabernanthine
0 ImagesTabernanthine is a negative chronotropic and negative inotropic agent that selectively acts on sinoatrial node receptors, regulating heart rhythm and myocardial contractility. Tabernanthine exhibits atropine resistance and direct non-cholinergic binding properties, acting directly on the sinoatrial node rather than relying on vagal nerve or cholinergic pathways to exert its key activity of slowing heart rate and weakening myocardial contractility. Tabernanthine is useful in cardiovascular pharmacology research, particularly in the areas of sinoatrial node function regulation, mechanisms related to bradycardia, and studies of cardiac receptor subtype differences. -
loading...Please select quantityAngebot einholen
August 31
-
Please select quantity
August 31
Angebot einholen
loading... -
-
Mesoridazine benzenesulfonate
0 ImagesArt. -Nr.: HY-B1482CAS. Nr.: 32672-69-8Synonyms: TPS-23 benzenesulfonateMesoridazine (TPS-23) benzenesulfonate, a metabolite of Thioridazine (HY-B0965A), acts as an orally active phenothiazine antipsychotic agent. Mesoridazine benzenesulfonate is a potent and rapid open-channel blocker of human ether-a-go-go related gene (hERG) channels and blocks hERG currents with an IC50 of 550 nM (at 0 mV) in human embryonic kidney 293 cells.Mesoridazine benzenesulfonate can be used for the research of schizophrenia, as well as certain other psychiatric disorders. -
loading...Please select quantityAngebot einholen
August 31
-
Please select quantity
August 31
Angebot einholen
loading... -
-
TMEM175 agonist 3
0 ImagesArt. -Nr.: HY-186257CAS. Nr.: 3129652-66-7TMEM175 agonist 3 (Compound 123) is a TMEM175 agonist, with an EC50 of 0.044 μM in human TMEM175 FLIPR assays and an EC50 of 0.073 μM in human TMEM175 EP assays. TMEM175 agonist 3 can be used in the research of Parkinson's disease, dementia with Lewy bodies, rapid eye movement sleep behavior disorder, amyotrophic lateral sclerosis, and lysosomal storage diseases. -
loading...Please select quantityAngebot einholen
August 31
-
Please select quantity
August 31
Angebot einholen
loading... -
-
Tedisamil dihydrochloride
0 ImagesArt. -Nr.: HY-126704ACAS. Nr.: 132523-84-3Synonyms: KC-8857 dihydrochlorideTedisamil (KC-8857) dihydrochloride is an antiarrhythmic compound with important biological activities. Tedisamil dihydrochloride exhibits a significant slowing effect on heart rate, which is achieved by inhibiting the transient outward potassium current (I(to)) in the atrium. Tedisamil dihydrochloride inhibits multiple potassium currents, including IK, K(ATP), and PKA-activated chloride channels, thereby prolonging the cardiac action potential and QT interval, and increasing cardiac reentry. Tedisamil dihydrochloride has antiarrhythmic effects on ventricular arrhythmias and atrial flutter in animal models. -
loading...Please select quantityAngebot einholen
August 31
-
Please select quantity
August 31
Angebot einholen
loading... -
-
Tyr-Somatostatin-28
0 ImagesArt. -Nr.: HY-P3898CAS. Nr.: 86649-84-5Tyr-Somatostatin-28 is a somatostatin that adds a Tyrosine amino acid to Somatostatin-28. -
loading...Please select quantityAngebot einholen
August 31
-
Please select quantity
August 31
Angebot einholen
loading... -
-
AY 31906
0 ImagesArt. -Nr.: HY-167082CAS. Nr.: 124788-46-1AY 31906 is an orally active pyrimidine sulfonamide diuretic. AY 31906 exhibits potent diuretic and natriuretic activities in rats and dogs, along with relatively potassium-sparing properties. AY 31906 exhibits superior activity to Furosemide (HY-B0135). AY-31906 also has antihypertensive effects and can be used in the research of cardiovascular diseases. -
loading...Please select quantityAngebot einholen
August 31
-
Please select quantity
August 31
Angebot einholen
loading... -
-
Brompheniramine maleate (Standard)
0 ImagesSynonyms: (±)-Brompheniramine maleate (Standard)Brompheniramine (maleate) (Standard) is the analytical standard of Brompheniramine (maleate). This product is intended for research and analytical applications. Brompheniramine ((±)-Brompheniramine) maleate is a potent and orally active antihistamine of the alkylamine class. Brompheniramine maleate is a selective histamine H1 receptor antagonist with a Kd of 6.06 nM. Brompheniramine maleate can block the hERG channels, calcium channels, and sodium channels with IC50s of 0.90 μM, 16.12 μM and 21.26 μM, respectively. Brompheniramine maleate has anticholinergic, antidepressant and anesthetic properties and can be used for allergic rhinitis research. -
loading...Please select quantityAngebot einholen
August 31
-
Please select quantity
August 31
Angebot einholen
loading... -
-
BMS-986308
0 ImagesArt. -Nr.: HY-162555CAS. Nr.: 2254333-97-4BMS-986308 is a selective and orally active renal outer medullary potassium (ROMK) channel inhibitor. BMS-986308 is selective for ROMK over hERG. BMS-986308 can be used for heart failure research. -
loading...Please select quantityAngebot einholen
August 31
-
Please select quantity
August 31
Angebot einholen
loading... -
- HUP30
-
loading...Please select quantityAngebot einholen
August 31
-
Please select quantity
August 31
Angebot einholen
loading... -
-
Antihypertensive agent 7
0 ImagesArt. -Nr.: HY-184303Antihypertensive agent 7 is a vasodilator. Antihypertensive agent 7 acts on vascular endothelial cells to activate the PI3K/AKT signaling axis, increase phosphorylated eNOS, release NO, activate the sGC/cGMP pathway in smooth muscle cells, and synergistically activate multiple K+ channels in vascular smooth muscle (Kir/Kv/KCa/KATP, thereby inducing endothelium-dependent vasodilation. Antihypertensive agent 7 can be used in the research of hypertension. -
loading...Please select quantityAngebot einholen
August 31
-
Please select quantity
August 31
Angebot einholen
loading... -
-
BA6b9
0 ImagesArt. -Nr.: HY-163735CAS. Nr.: 609335-29-7BA6b9 is an allosteric inhibitor of SK4 channels that targets the CaM–PIP2-binding domain with a IC50 value of 8.6 µM (WT SK4). BA6b9 inhibits SK4 channels by interacting with two specific residues, Arg191 and His192 in the S4–S5 linker. BA6b9 significantly prolongs atrial and atrioventricular effective refractory period (ERP) and reduces atrial fibrillation (AF) induction in rat isolated hearts, which has the potential to be used for the research of arrhythmia . -
loading...Please select quantityAngebot einholen
August 31
-
Please select quantity
August 31
Angebot einholen
loading... -
-
HCN-IN-1
0 ImagesArt. -Nr.: HY-186062CAS. Nr.: 2234283-04-4HCN-IN-1 is a TLR4 inhibitor and HCN channel modulator with activity against HCN2 and HCN4.HCN-IN-1 inhibits TLR4-mediated alkaline phosphatase (SEAP) signal activity.HCN-IN-1 reduces HCN2 current across tested voltages, shifts voltage-dependent activation to more hyperpolarized potentials, slows activation kinetics, and does not affect deactivation process.HCN-IN-1 blocks HCN4 current.HCN-IN-1 exhibits analgesic, anti-inflammatory, and anti-anginal effects.HCN-IN-1 can be used for the research of inflammatory pain, neuropathic pain, heart failure, inflammation. -
loading...Please select quantityAngebot einholen
August 31
-
Please select quantity
August 31
Angebot einholen
loading... -
-
CP-339818
0 ImagesArt. -Nr.: HY-114540CAS. Nr.: 185855-91-8CP-339818 is a non-peptide Kv1.3 channel (IC50 = 200 nM) and Kv1.4 channel blocker. CP 339818 inhibits HCN channel with IC50s of 18.9 μM and 43.4 μM against HCN1 and HCN4 (high Cl-). CP-339818 has significantly weaker blocking effects on Kv1.1, Kv1.2, Kv1.5, Kv1.6, Kv3.1-4, and Kv4.2 channels. CP-339818 selectively blocked Kv1.3, thereby inhibiting the activation process of human T cells. CP-339818 can be used to study the physiological functions of HCN and Kv channels. -
loading...Please select quantityAngebot einholen
August 31
-
Please select quantity
August 31
Angebot einholen
loading... -
-
Ipidacrine-d10
0 ImagesArt. -Nr.: HY-W027553S1Synonyms: NIK-247-d9 free baseIpidacrine-d9 (NIK-247-d9 (free base)) is the deuterium labeled Ipidacrine (HY-W027553). Ipidacrine is orally active and brain-penetrant AChE and BuChE inhibitors with IC50 values of 1 μM and 1.9 μM, respectively, which is also a partial agonist of M2-cholinergic receptors and a reversible cholinesterase inhibitor. Ipidacrine has a stimulating effect on neuromuscular transmission and excitation along the nerve fibres with a moderately anti-pain effect. Ipidacrine is an aminopyridines and is structurally similar to Tacrine (HY-111338). Ipidacrine is effective in various amnesia models, improves erectile function and inhibits K+ and Na+-channels in the neuronal membrane in diabetic rats. Ipidacrine is promising for research of Alzheimer’s disease, ischaemic stroke, idiopathic neuropathy of the facial nerve, diabetes mellitus-induced erectile dysfunction and other deficits in central or peripheral cholinergic deseases. -
loading...Please select quantityAngebot einholen
August 31
-
Please select quantity
August 31
Angebot einholen
loading... -
No matching results
No matching results
No matching results
No matching results
No matching results
No matching results
No matching results
No matching results
No matching results
No matching results