Reference Standards
Material, sufficiently homogeneous and stable with respect to one or more specified properties, and the uses include the calibration of a measurement system, assessment of a measurement procedure, assigning values to other materials, and quality control and so on.
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Reference Standards Verwandte Produkte (11771)
Verwandte Produkte (11771)
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APS-2-79 (Standard)
0 ImagesAPS-2-79 (Standard) is the analytical standard of APS-2-79 (HY-100627). This product is intended for research and analytical applications. APS-2-79 is a KSR-dependent MEK antagonist. APS-2-79 inhibits ATPbiotin binding to KSR2 within the KSR2-MEK1 complexe with an IC50 of 120 nM. APS-2-79 makes the stabilization of the KSR inactive state antagonizes oncogenic Ras-MAPK signaling.
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Regorafenib (Standard)
0 ImagesSynonyms: BAY 73-4506 (Standard)Regorafenib (Standard) is the analytical standard of Regorafenib. This product is intended for research and analytical applications. Regorafenib (BAY 73-4506) is an orally active and potent multi-targeted receptor tyrosine kinase inhibitor, with IC50 values of 13/4.2/46, 22, 7, 1.5 and 2.5 nM for VEGFR1/2/3, PDGFRβ, Kit, RET and Raf-1, respectively. Regorafenib shows very robust antitumor and antiangiogenic activity.
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Lanatoside C (Standard)
0 ImagesLanatoside C (Standard) is the analytical standard of Lanatoside C. This product is intended for research and analytical applications. Lanatoside C is a cardiac glycoside, can be used in the treatment of congestive heart failure and cardiac arrhythmia.Lanatoside C has an IC50 of 0.19 μM for dengue virus infection in HuH-7 cells. Lanatoside C can effectively inhibit all four serotypes of dengue virus, flavivirus Kunjin, alphavirus Chikungunya, Sindbis virus and the human enterovirus 71.
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Theliatinib (Standard)
0 ImagesArt. -Nr.: HY-104066RCAS. Nr.: 1353644-70-8Synonyms: Xiliertinib (Standard); HMPL-309 (Standard)Theliatinib (Standard) is the analytical standard of Theliatinib (HY-104066). This product is intended for research and analytical applications. Theliatinib (Xiliertinib) is a potent, ATP-competitive, orally active and highly selective EGFR inhibitor with a Ki of 0.05 nM and an IC50 of 3 nM. Theliatinib has an IC50 of 22 nM for EGFR T790M/L858R mutant. Theliatinib shows >50-fold selectivity for EGFR than other kinases. Theliatinib is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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Enavogliflozin (Standard)
0 ImagesArt. -Nr.: HY-109144RCAS. Nr.: 1415472-28-4Synonyms: DWP-16001 (Standard)Enavogliflozin (Standard) is the analytical standard of Enavogliflozin (HY-109144). This product is intended for research and analytical applications. Enavogliflozin (DWP-16001), an antidiabetic agent, is an orally active, best-in-class and selective sodium-glucose cotransporter-2 (SGLT-2) inhibitor.
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MPP dihydrochloride (Standard)
0 ImagesArt. -Nr.: HY-103454RCAS. Nr.: 911295-24-4MPP dihydrochloride (Standard) is the analytical standard of MPP dihydrochloride (HY-103454). This product is intended for research and analytical applications. MPP dihydrochloride is a potent and selective ER (estrogen receptor) modulator. MPP dihydrochloride induces significant apoptosis in the endometrial cancer and oLE cell lines. MPP dihydrochloride reverses the positive effects of beta-estradiol. MPP dihydrochloride has mixed agonist/antagonist action on murine uterine ERalpha in vivo.
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Homo-PROTAC cereblon degrader 1 (Standard)
0 ImagesArt. -Nr.: HY-111594RCAS. Nr.: 2244520-98-5Homo-PROTAC cereblon degrader 1 (Standard) is the analytical standard of Homo-PROTAC cereblon degrader 1 (HY-111594). This product is intended for research and analytical applications. Homo-PROTAC cereblon degrader 1 is a highly selective cereblon (CRBN) PROTAC degrader. Homo-PROTAC cereblon degrader 1 induces self-directed ubiquitination and proteasomal degradation of CRBN. Homo-PROTAC cereblon degrader 1 blocks Pomalidomide (HY-10984)-induced degradation of IKZF1 and IKZF3. Homo-PROTAC cereblon degrader 1 antagonizes the growth inhibitory effect of Pomalidomide on multiple myeloma cells. Homo-PROTAC cereblon degrader 1 can be used in studies related to multiple myeloma.
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Boc-Asp(OMe)-fluoromethyl ketone (Standard)
0 ImagesArt. -Nr.: HY-103348RCAS. Nr.: 187389-53-3Synonyms: Boc-Asp(OMe)-FMK (Standard)Boc-Asp(OMe)-fluoromethyl ketone (Standard) is the analytical standard of Boc-Asp(OMe)-fluoromethyl ketone (HY-103348). This product is intended for research and analytical applications. Boc-Asp(OME)-Fluoromethyl Ketone is a broad range caspase inhibitor that inhibits Fas-mediated phagocytosis and oxidative rupture inhibition, but does not affect the chemotactic activity of IL-8.
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Iloprost (Standard)
0 ImagesArt. -Nr.: HY-A0096RCAS. Nr.: 78919-13-8Synonyms: Ciloprost (Standard); ZK 36374 (Standard)Iloprost (Standard) is the analytical standard of Iloprost. This product is intended for research and analytical applications. Iloprost (ZK 36374; Ciloprost) is a prostacyclin (PGI2) analogue, involves in embryo development and inflammation improvement, and inhibits tumor metastasis. Iloprost can be used for peripheral vascular research.
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PROTAC Sirt2 Degrader-1 (Standard)
0 ImagesArt. -Nr.: HY-103636RCAS. Nr.: 2098487-75-1PROTAC Sirt2 Degrader-1 (Standard) is the analytical standard of PROTAC Sirt2 Degrader-1 (HY-103636). This product is intended for research and analytical applications. PROTAC Sirt2 Degrader-1 is a SirReal-based PROTAC, acts as a Sirt2 degrader, composed of a highly potent and isotype-selective Sirt2 inhibitor, a linker, and a bona fide Cereblon ligand for E3 ubiquitin ligase. PROTAC Sirt2 Degrader-1 shows an IC50 of 0.25 μM for Sirt2, with no effect on Sirt1/Sirt3 (IC50s>100 μM).
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Pranidipine (Standard)
0 ImagesSynonyms: OPC-13340 (Standard)Pranidipine (Standard) is the analytical standard of Pranidipine. This product is intended for research and analytical applications. Pranidipine (OPC-13340) is a potent, long acting 1,4-dihydropyridine calcium channel blocker with antihypertensive activity.
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Rosiglitazone hydrochloride (Standard)
0 ImagesSynonyms: BRL 49653 hydrochloride (Standard)Rosiglitazone (hydrochloride) (Standard) is the analytical standard of Rosiglitazone (hydrochloride). This product is intended for research and analytical applications. Rosiglitazone (BRL 49653) hydrochloride is an orally active selective PPARγ agonist (EC50: 60 nM, Kd: 40 nM). Rosiglitazone hydrochloride is a TRPC5 activator (EC50: 30 μM) and TRPM3 inhibitor. Rosiglitazone hydrochloride can be used in the research of obesity and diabetes, senescence, ovarian cancer.
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VULM 1457 (Standard)
0 ImagesArt. -Nr.: HY-107571RCAS. Nr.: 228544-65-8VULM 1457 (Standard) is the analytical standard of VULM 1457 (HY-107571). This product is intended for research and analytical applications. VULM 1457 is a potent inhibitor of cholesterol acyltransferase (acyl-CoA). VULM1457 significantly reduces production and secretion of adrenomedullin (AM) and down-regulates AM receptors on human hepatoblastic cells. VULM 1457 has remarkable hypolipidaemic activity and improves the overall myocardial ischaemia-reperfusion injury outcomes. VULM 1457 has the potential for the research of diabetes mellitus and hypercholesterolaemia.
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L-Aspartic aicd sodium (Standard)
0 ImagesArt. -Nr.: HY-N0666CRCAS. Nr.: 3792-50-5Synonyms: Sodium L-aspartate (Standard)L-Aspartic aicd sodium (Standard) (Sodium L-aspartate (Standard)) is the analytical standard of L-Aspartic aicd sodium (HY-N0666C). This product is intended for research and analytical applications. L-Aspartic acid sodium (Sodium L-aspartate) is a NMDA receptor agonist and acidic amino acid. L-Aspartic acid sodium has no independent analgesic activity. L-Aspartic acid sodium can antagonize the analgesic effects of D-Aspartic acid and Morphine. L-Aspartic acid sodium regulates polymorph transformation, crystal growth/aggregation and nucleation processes of calcium carbonate, and can serve as a biomineralization template. L-Aspartic acid sodium promotes burst firing of central neurons. L-Aspartic acid sodium can be used in studies related to cerebral ischemia and epilepsy.
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Lanoconazole (Standard)
0 ImagesArt. -Nr.: HY-14282RCAS. Nr.: 101530-10-3Lanoconazole (Standard) is the analytical standard of Lanoconazole. This product is intended for research and analytical applications. Lanoconazole is a potent and orally active imidazole antifungal agent, shows a broad spectrum of activity against fungi in vitro and in vivo. Lanoconazole interferes with ergosterol biosynthesis by inhibiting sterol 14-alpha demethylase and blocking fungal membrane ergosterol biosynthesis. Lanoconazole can be used for the investigation of dermatophytosis and onychomycosis.
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ML349 (Standard)
0 ImagesML349 (Standard) is the analytical standard of ML349 (HY-100737). This product is intended for research and analytical applications. ML349 is a potent and specific acyl protein thioesterase 2(APT2)/lysophospholipase 2 (LYPLA2) inhibitor with a Ki of 120 nM. ML349 is also an inhibitor of LYPLA2 with an IC50 of 144 nM.
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PA452 (Standard)
0 ImagesArt. -Nr.: HY-108522RCAS. Nr.: 457657-34-0
