2. Signaling Pathways
  3. Cytoskeleton
  4. Collagen
  5. Collagen Activator

Collagen Activator

Collagen Activators (12):

Cat. No. Product Name Effect Purity
  • HY-171657
    4'-Acetoxy resveratrol
    		Activator 99.90%
    4'-Acetoxy resveratrol is a Resveratrol (HY-16561) derivative. 4'-Acetoxy resveratrol upregulates gene expression of elastin, collagen types III and IV, superoxide dismutase (SOD), and catalase (CAT), while downregulating interleukins (IL-1A, IL-1R2, IL-6, IL-8) and cyclooxygenase-2 (COX-2) in human skin models. 4'-Acetoxy resveratrol can be used for skin reasearch.
  • HY-W014075
    1-Hydroxypyrene
    		Activator 98.78%
    1-Hydroxypyrene, a biomarker of exposure to polycyclic aromatic hydrocarbons (PAHs), is analyzed in urine samples. 1-Hydroxypyrene is the major biomarker of exposure to pyrenes. 1-Hydroxypyrene is the orally active agonist for aryl hydrocarbon receptor (AhR) and can lead to renal fibrosis.
  • HY-N0363
    (+)-Columbianetin
    		Activator 99.04%
    (+)-Columbianetin ((S)-Columbianetin) acts as an inhibitor of JNK/ERK. (+)-Columbianetin inhibits UVA-induced phosphorylation of JNK and ERK, reduces the production of MMP-1, reverses UVA-induced Collagen (HY-NP003) degradation, and alleviates UVA-mediated inhibition of Smad2/3 phosphorylation and translocation. (+)-Columbianetin regulates the AP-1 and ASK1-MAPK signaling pathways, inhibits the production of ROS and blocks sub-G1 cell cycle arrest. (+)-Columbianetin is applicable to research related to skin aging.
  • HY-P3163
    Hexapeptide-9
    		Activator 99.28%
    Hexapeptide-9 is a signaling peptide. Hexapeptide-9 can promote collagen production. Hexapeptide-9 has anti-aging activity, and can be used in cosmetic research.
  • HY-W014075S
    1-Hydroxypyrene-d9
    		Activator 99.95%
    1-Hydroxypyrene-d9 is the deuterium labeled 1-Hydroxypyrene (HY-W014075). 1-Hydroxypyrene, a biomarker of exposure to polycyclic aromatic hydrocarbons (PAHs), is analyzed in urine samples. 1-Hydroxypyrene is the major biomarker of exposure to pyrenes. 1-Hydroxypyrene is the orally active agonist for aryl hydrocarbon receptor (AhR) and can lead to renal fibrosis.
  • HY-P0104
    Palmitoyl tripeptide-38
    		Activator 99.83%
    Palmitoyl tripeptide-38 is a lipopeptide that increases the production of dermal and epidermal collagen, fibronectin, and hyaluronic acid. Palmitoyl tripeptide-38 is used in research related to skin aging (fine lines, wrinkles, reduced skin elasticity, decreased skin water content, uneven skin tone).
  • HY-P5237
    Tetrapeptide-4
    		Activator 99.54%
    Tetrapeptide-4 is a synthetic tetrapeptide. Tetrapeptide-4 upregulates hyaluronic acid synthetase, and collagen production in human dermal fibroblasts. Tetrapeptide-4 reduces skin aging, improves skin firmness, elasticity, and appearance, and benefits hair.
  • HY-P5239
    Myristoyl pentapeptide-4
    		Activator 98.86%
    Myristoyl pentapeptide-4 is a bioactive peptide with promotion of hair growth effect and has been reported used as a cosmetic ingredient.
  • HY-W014075R
    1-Hydroxypyrene (Standard)
    		Activator
    1-Hydroxypyrene (Standard) is the analytical standard of 1-Hydroxypyrene (HY-W014075). This product is intended for research and analytical applications. 1-Hydroxypyrene, a biomarker of exposure to polycyclic aromatic hydrocarbons (PAHs), is analyzed in urine samples. 1-Hydroxypyrene is the major biomarker of exposure to pyrenes. 1-Hydroxypyrene is the orally active agonist for aryl hydrocarbon receptor (AhR) and can lead to renal fibrosis.
  • HY-126956
    Porphyra 334
    		Activator
    Porphyra 334 is a carnosine-like amino acid and a natural photoprotective agent and antioxidant. Porphyra-334 exerts its photoprotective effects by scavenging ROS, inhibiting the expression and activity of MMP-1/8, and promoting the synthesis of collagen and elastin. Porphyra 334 effectively inhibits linoleic acid oxidation induced by alkyl radicals (AAPH) and singlet oxygen. Porphyra 334 has anti-obesity potential by inhibiting the expression of PPARγ2 and C/EBPα. Porphyra 334 protects cells against UV-induced DNA damage and apoptosis by inhibiting the activation of caspase-3.
  • HY-148854
    L-Ascorbate sulfate disodium
    		Activator
    L-Ascorbate-2-sulfate disodium (page 46) is a pharmacologically acceptable salt of the L-Ascorbic acid (HY-B0166G) derivative. L-Ascorbate-2-sulfate disodium stimulates collagen synthesis and possess skin-care functions including an elimination function of active oxygen.
  • HY-W404758
    Calcium glucoheptonate
    		Activator
    Calcium glucoheptonate is a highly water-soluble calcium supplement. Calcium glucoheptonate can increase the proliferation rate and Calcium intake of MG-63 cells and increase the activity of alkaline phosphatase (ALP). Calcium glucoheptonate can upregulate the expression of osteogenic-related genes and proteins,such as collagen-1, osteocalcin and osteocalcin. Calcium glucoheptonate can be used for the researches of osteoporosis and hypocalcemia.