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  3. Reference Standards Epigenetic Reader Domain Histone Acetyltransferase
  4. A-485 (Standard)

A-485 (Standard) is the analytical standard of A-485 (HY-107455). This product is intended for research and analytical applications. A-485, a chemical probe, is a potent and selective catalytic inhibitor of p300/CBP with IC50s of 9.8 nM and 2.6 nM for p300 and CBP histone acetyltransferase (HAT), respectively.

For research use only. We do not sell to patients.

A-485 (Standard)

A-485 (Standard) Chemical Structure

CAS No. : 1889279-16-6

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A-485 (Standard) Related Antibodies

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Description

A-485 (Standard) is the analytical standard of A-485 (HY-107455). This product is intended for research and analytical applications. A-485, a chemical probe, is a potent and selective catalytic inhibitor of p300/CBP with IC50s of 9.8 nM and 2.6 nM for p300 and CBP histone acetyltransferase (HAT), respectively[1].

IC50 & Target

IC50: 9.8 nM (p300), 2.6 nM (CBP)[1]
Molecular Weight

536.48

Formula

C25H24F4N4O5
CAS No.
Appearance

Solid

Color

White to light yellow

SMILES

O=C(N1CC(N([C@@H](C)C(F)(F)F)CC2=CC=C(F)C=C2)=O)[C@]3(OC1=O)C4=CC=C(NC(NC)=O)C=C4CC3
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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A-485 (Standard) Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

A-485 (Standard)1889279-16-6Reference StandardsEpigenetic Reader DomainHistone AcetyltransferaseHATsHATInhibitorinhibitorinhibit

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