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Art. -Nr.: HY-184877

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CDK4-IN-8

CDK4-IN-8 is a selective CDK4 inhibitor with no activity against CDK6, and it inhibits the proliferation of breast cancer cells. CDK4-IN-8 can be used in breast cancer-related research.

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CAS. Nr.: 2764984-10-1
Formel: C₂₇H₃₁FN₆OS
Molecular Weight:506.64

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

CDK4-IN-8 Chemical Structure

CAS. Nr.: 2764984-10-1

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Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biologische Aktivität
- Beschreibung
- IC₅₀ & Target
- In Vitro
Chemical Information
Reinheit & Dokumentation
Verweise
Calculators
Help & FAQs
Classifications
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Biologische Aktivität

Beschreibung

CDK4-IN-8 is a selective CDK4 inhibitor with no activity against CDK6, and it inhibits the proliferation of breast cancer cells. CDK4-IN-8 can be used in breast cancer-related research^[1].

IC₅₀ & Target^[1]

CDK4

Alle CDK Isoform-spezifische Produkte anzeigen :

In Vitro

CDK4-IN-8 (example 98) exhibits potent inhibitory activity against CDK4_D1 kinase, shows moderate antiproliferative activity against MCF7 adenocarcinoma cells, and has no obvious inhibitory activity against CDK6_D1 kinase^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS. Nr. 2764984-10-1
Molecular Weight 506.64
Formel C₂₇H₃₁FN₆OS
SMILES

O=C1C2=C(SC(C=3N=C(N=CC3F)NC4=NC=C(C=C4)C5CCN(C)CC5)=C2C)C(=CN1C)C(C)C
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Handling Instructions (2659 KB)

Verweise

[1]. Buesking A W, et al. Cdk inhibitors and their use as pharmaceuticals. WO2022061273A1. WIPO. 2022.

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biologische Aktivität
- Beschreibung
- IC₅₀ & Target
- In Vitro
Chemical Information
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CDK4-IN-8

Alle CDK Isoform-spezifische Produkte anzeigen

Biologische Aktivität

Chemical Information

Reinheit & Dokumentation

Verweise

Calculators

Help & FAQs

CDK4-IN-8 Related Classifications

HY-184877 Related Classifications