K11002 hydrobromide
K11002 hydrobromide is a cysteine protease inhibitor. K11002 hydrobromide forms a covalent bond with the active site cysteine residue via Michael addition. K11002 hydrobromide inhibits the growth of Trypanosoma brucei. K11002 hydrobromide can be used in the research of African human trypanosomiasis (sleeping sickness).
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- CAS. Nr.: 1348565-08-1
- Formel: C31H36BrN3O5S
- Molecular Weight:642.60
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
Hydrobromide form of K11002 (24 h potently inhibits the growth of bloodstream-form and anterior-circulation-form Trypanosoma brucei, with ED50 values of 4.1 nM and 7.0 nM respectively after 24 h of incubation[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS. Nr. 1348565-08-1
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Molecular Weight 642.60
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Formel C31H36BrN3O5S
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SMILES
O=S(/C=C/[C@H](CCC1=CC=CC=C1)NC([C@@H](NC(N2CCOCC2)=O)CC3=CC=CC=C3)=O)(C4=CC=CC=C4)=O.Br
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)