M199
Based on 1 Customer Validation
M199 is a potent TLR3/TLR9 signaling inhibitor. M199 induces secretion of IL-6, IL-8 and TNFα in human PBMCs. M199 is used as a selective inducer of the immune response.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- Reinheit: 98.55%
- CAS. Nr.: 1051933-86-8
- Formel: C17H17N3O
- Molecular Weight:279.34
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Speicherung:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biologische Aktivität
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Chemical Information
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Lösungsmittel & Löslichkeit
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Alle TNF Receptor Isoform-spezifische Produkte anzeigen
More
Biologische Aktivität
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TLR3 |
TLR9 |
IL-6 |
IL-8 |
Chemical Information
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CAS. Nr. 1051933-86-8
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Appearance Solid
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Molecular Weight 279.34
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Formel C17H17N3O
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Color Yellow to brown
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SMILES
O=C(NCC)NC1=CC2=C(N=C3C=CC=CC3=C2C=C1)C
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Lösungsmittel & Löslichkeit
DMSO : 5.83 mg/mL (20.87 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Reinheit & Dokumentation
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Data Sheet (271 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
Verweise
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.5799 mL | 17.8993 mL | 35.7987 mL | 89.4967 mL |
| 5 mM | 0.7160 mL | 3.5799 mL | 7.1597 mL | 17.8993 mL | |
| 10 mM | 0.3580 mL | 1.7899 mL | 3.5799 mL | 8.9497 mL | |
| 15 mM | 0.2387 mL | 1.1933 mL | 2.3866 mL | 5.9664 mL | |
| 20 mM | 0.1790 mL | 0.8950 mL | 1.7899 mL | 4.4748 mL |
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