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Cat. No.: HY-P11576

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Cyclic αvβ6

Cyclic αvβ6 (Compound c(FRGDLAFp(NMe)K)) is a αvβ6-integrin-specific cyclic nonapeptide. Cyclic αvβ6 can be coupled with ⁶⁸Ga-labeled monomeric triazacyclononane-triphosphinate (TRAP). Cyclic αvβ6 can be used in PET imaging studies for cancers including head and neck cancer and pancreatic cancer.

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CAS No.: 2089299-82-9
Formule: C₅₁H₇₅N₁₃O₁₁
Masse moléculaire:1046.22

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Please store the product under the recommended conditions in the Certificate of Analysis.

Cyclic αvβ6 Chemical Structure

CAS No.: 2089299-82-9

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- Description
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Chemical Information
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Activité biologique

Description

IC₅₀ & Target^[1]

αvβ6

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Chemical Information

CAS No. 2089299-82-9
Masse moléculaire 1046.22
Formule C₅₁H₇₅N₁₃O₁₁
Sequence

c(Phe-Arg-Gly-Asp-Leu-Ala-Phe-DPro(NMe)-Lys)
Sequence Shortening

c(FRGDLAF-DPro(NMe)-K)
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (259 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Quigley NG, et al. PET/CT imaging of head-and-neck and pancreatic cancer in humans by targeting the "Cancer Integrin" αvβ6 with Ga-68-Trivehexin. Eur J Nucl Med Mol Imaging. 2022 Mar;49(4):1136-1147. [Content Brief]

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Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Cyclic αvβ6

Voir tous les produits spécifiques à Isoform Integrin

Voir tous les produits spécifiques à Isoform Radionuclide-Drug Conjugates (RDCs)

Activité biologique

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

Cyclic αvβ6 Related Classifications

HY-P11576 Related Classifications