K11002 hydrobromide
K11002 hydrobromide is a cysteine protease inhibitor. K11002 hydrobromide forms a covalent bond with the active site cysteine residue via Michael addition. K11002 hydrobromide inhibits the growth of Trypanosoma brucei. K11002 hydrobromide can be used in the research of African human trypanosomiasis (sleeping sickness).
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- CAS No.: 1348565-08-1
- Formule: C31H36BrN3O5S
- Masse moléculaire:642.60
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
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Activité biologique
Hydrobromide form of K11002 (24 h potently inhibits the growth of bloodstream-form and anterior-circulation-form Trypanosoma brucei, with ED50 values of 4.1 nM and 7.0 nM respectively after 24 h of incubation[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 1348565-08-1
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Masse moléculaire 642.60
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Formule C31H36BrN3O5S
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SMILES
O=S(/C=C/[C@H](CCC1=CC=CC=C1)NC([C@@H](NC(N2CCOCC2)=O)CC3=CC=CC=C3)=O)(C4=CC=CC=C4)=O.Br
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
K11002 hydrobromide Related Classifications
HY-183387 Related Classifications
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