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Meropenem

(Synonyms: SM 7338)
34 Cited Publications
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Based on 34 publication(s) in Google Scholar

Meropenem (SM 7338) is a carbapenem antibiotic with broad-spectrum antibacterial activity. Meropenem has activity against susceptible and resistant N. gonorrhoeae (MIC value of 0.02-0.06 mg/mL), H. influenzae (MIC value of 0.03-0.12 mg/mL), and H. ducreyi (MIC value of 0.015-0.12 mg/mL).

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  • Pureté: 99.85%
  • CAS No.: 96036-03-2
  • Formule: C17H25N3O5S
  • Masse moléculaire:383.46
  • Stockage:
    Powder   -20°C, 3 years , 4°C, 2 years ; In solvent   -80°C, 6 months , -20°C, 1 month
  • Meropenem Chemical Structure
    Meropenem Chemical Structure
  • Experimental Validation Results for Meropenem
  • Experimental Validation Results for Meropenem
  • Experimental Validation Results for Meropenem
  • Experimental Validation Results for Meropenem
  • Experimental Validation Results for Meropenem
  • Experimental Validation Results for Meropenem
  • Experimental Validation Results for Meropenem
CAS No.: 96036-03-2
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  • Meropenem Chemical Structure
    Meropenem Chemical Structure
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    Meropenem purchased from MedChemExpress. Usage Cited in: mLife. 2025 Apr 15;4(2):155-168. [Abstract]

    Customer Validation
     Treatment of wild-type BCG with the ClpP-targeting compound GDI-5755 and Ethambutol (ETH) or Meropenem (MPM) significantly reduced the minimum inhibitory concentration (MIC) of each drug.

  • 1/16

    Meropenem purchased from MedChemExpress. Usage Cited in: BMC Microbiol. 2025 Apr 29;25(1):257. [Abstract]

    Customer Validation
     To evaluate the influence of various concentrations of xylose on the antimicrobial susceptibility of K. pneumoniae, the MIC values of K. pneumoniaetoward commonly used antibiotics, including Meropenem, Gentamicin, and Ceftriaxone, were determined after xylose exposure at various concentrations.

  • 1/16

    Meropenem purchased from MedChemExpress. Usage Cited in: Emerg Microbes Infect. 2024 Dec;13(1):2321981. [Abstract]

    Customer Validation
     Antibacterial activity of AMXT-1501 against K. pneumoniae, an ESBL-producing E. coli, and carbapenem-resistant Enterobacteriaceae E. coli detected by time-killing assays; compared with meropenem or tigecycline (final concentration at 8× MIC); The dashed lines indicated the limit of detection of time-killing assays. Antibacterial activity of AMXT-1501 against abdominal infected with E. coli ECO2219 (n = 15/group); compared with TIG.

  • 1/16

    Meropenem purchased from MedChemExpress. Usage Cited in: Microorganisms. 2024 Mar 13;12(3):575. [Abstract]

    Customer Validation
     Percentages of E. coli strains showing antimicrobial resistance to different antimicrobial agents. AMP, Ampicillin; CAZ, Ceftazidime; IPM, Imipenem; MRP, Meropenem; GEN, Gentamicin; OFX, Ofloxacin; SXT, Trimethoprim–sulfamethoxazole; TET, Tetracycline; TGC, Tigecycline; CL, Colistin; FFC, Florfenicol.

  • 1/16

    Meropenem purchased from MedChemExpress. Usage Cited in: Open Forum Infect Dis. 2023 Jan 27;10(2):ofad038. [Abstract]

    Customer Validation
     Ceftazidime-avibactam, Meropenem, and Imipenem were the most active β-lactam agents tested against 2663 ESBL-producing E. coli and K. pneumoniae isolates that were carbapenem susceptible

  • 1/16

    Meropenem purchased from MedChemExpress. Usage Cited in: Nat Commun. 2022 Mar 2;13(1):1116. [Abstract]

    Customer Validation
     Resistance rates of Escherichia coli isolates from farms in different provinces of mainland China to different classes of antibiotics, including Meropenem.

  • 1/16

    Meropenem purchased from MedChemExpress. Usage Cited in: J Antimicrob Chemother. 2020 Jul 1;75(7):1850-1858. [Abstract]

    Customer Validation
     The cumulative MIC distributions of Cefepime/Taniborbactam, Ceftazidime/Avibactam and comparator Meropenem for 500 tested isolates. The MICs of cefepime and Cefepime/Taniborbactam shown in the figure were tested by the broth microdilution method. The MICs of Meropenem shown in the figure were tested by the agar dilution method. SS, susceptible to all tested β-lactams. SS-P. aeruginosa, meropenem-susceptible P. aeruginosa. Nine IMP producers included three blaIMP-producing P. aeruginosa.

  • Meropenem