(R)-Hydroxychloroquine
(R)-Hydroxychloroquine is the enantiomer of Hydroxychloroquine. Hydroxychloroquine is a synthetic antimalarial agent which can also inhibit Toll-like receptor 7/9 (TLR7/9) signaling. Hydroxychloroquine is efficiently inhibits SARS-CoV-2 infection in vitro.
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- CAS No.: 137433-23-9
- Formule: C18H26ClN3O
- Masse moléculaire:335.87
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
- Protocole
- Pureté et documentation
- Références
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Activité biologique
Description
IC50 & Target
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Plasmodium |
TLR7 |
TLR9 |
Chemical Information
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CAS No. 137433-23-9
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Masse moléculaire 335.87
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Formule C18H26ClN3O
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SMILES
CCN(CCO)CCC[C@H](NC1=CC=NC2=CC(Cl)=CC=C12)C
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Synonyms
(R)-HCQ
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
[1]. Cardoso CD, et al. Enantioselective analysis of the metabolites of hydroxychloroquine and application to an in vitro metabolic study. J Pharm Biomed Anal. 2005 Apr 1;37(4):703-8. [Content Brief]
[2]. Manzo C, et al. Psychomotor Agitation Following Treatment with Hydroxychloroquine. Drug Saf Case Rep. 2017 Dec;4(1):6. [Content Brief]
[3]. . Lamphier M, et al. Novel small molecule inhibitors of TLR7 and TLR9: mechanism of action and efficacy in vivo. Mol Pharmacol. 2014 Mar;85(3):429-40. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
(R)-Hydroxychloroquine Related Classifications
HY-B1370B Related Classifications
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