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Cat. No.: HY-112384

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Safingol

(Synonyms: L-threo-dihydrosphingosine)

Safingol is a lyso-sphingolipid PKC (protein kinase C ) inhibitor.

Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.

CAS No.: 15639-50-6
Formule: C₁₈H₃₉NO₂
Masse moléculaire:301.51

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (260 KB)

Safingol Chemical Structure

CAS No.: 15639-50-6

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- Essai clinique
Chemical Information
Pureté et documentation
Références
Calculators
Help & FAQs
Classifications
Bioz

Activité biologique

Description

Safingol is a lyso-sphingolipid PKC (protein kinase C ) inhibitor^[1].

Voir tous les produits spécifiques à Isoform PKC :

Essai clinique

NCT Number	Sponsor	Condition	Start Date	Phase A549
NCT01329991	Plexxikon\|		2011-05	PHASE1

Chemical Information

CAS No. 15639-50-6
Masse moléculaire 301.51
Formule C₁₈H₃₉NO₂
SMILES

CCCCCCCCCCCCCCC[C@H](O)[C@@H](N)CO
Synonyms

L-threo-dihydrosphingosine
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (260 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Tsukamoto S, et al. Sphingosine Kinase-1 Protects Multiple Myeloma from Apoptosis Driven by Cancer-Specific Inhibition of RTKs. Mol Cancer Ther. 2015 Oct;14(10):2303-12. [Content Brief]

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Activité biologique
- Description
- Essai clinique
Chemical Information
Pureté et documentation
Références

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Safingol

High-Throughput Bioactive Compound Library

Voir tous les produits spécifiques à Isoform PKC

Activité biologique

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

Safingol Related Classifications

HY-112384 Related Classifications