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Art. -Nr.: HY-136733

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Ac-DNLD-CHO

Name: Ac-DNLD-CHO
Brand: MedChemExpress
SKU: HY-136733
Availability: PreOrder

(Synonyms: Ac-Asp-Asn-Leu-Asp-CHO)

2 Cited Publications

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Based on 2 publication(s) in Google Scholar

Ac-DNLD-CHO (Ac-Asp-Asn-Leu-Asp-CHO) is a Caspase-3/7 inhibitor (IC₅₀: 9.89, 245 nM respectively; K_i^app: 0.68, 55.7 nM respectively). Ac-DNLD-CHO can be used for research of caspase-mediated apoptosis diseases, such as neurodegenerative disorders and viral infection diseases.

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CAS. Nr.: 775289-20-8
Formel: C₂₀H₃₁N₅O₁₀
Molecular Weight:501.49

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

Ac-DNLD-CHO Chemical Structure

CAS. Nr.: 775289-20-8

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biologische Aktivität
- Beschreibung
- IC₅₀ & Target
Chemical Information
Publications (2)
Reinheit & Dokumentation
Verweise
Calculators
Help & FAQs
Classifications
Bioz

Biologische Aktivität

Beschreibung

IC₅₀ & Target

Caspase-3/7^[1]

Alle Caspase Isoform-spezifische Produkte anzeigen :

Chemical Information

CAS. Nr. 775289-20-8
Molecular Weight 501.49
Formel C₂₀H₃₁N₅O₁₀
Synonyms

Ac-Asp-Asn-Leu-Asp-CHO
Sequence

Ac-Asp-Asn-Leu-Asp-CHO
Sequence Shortening

Ac-DNLD-CHO
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Publications (2)

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Journal Impact Factor

Nat Commun

Cleavage of CAD by caspase-3 determines the cancer cell fate during chemotherapy. [Abstract]

2025 May 30;16(1):5006. PMID: 40442064
Res Sq

2024 Aug 11.

Reinheit & Dokumentation

Select Batch:

Reinheit: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (268 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

Verweise

[1]. Yoshimori A, et al. Structural and functional definition of the specificity of a novel caspase-3 inhibitor, Ac-DNLD-CHO. BMC Pharmacol. 2007 Jun 27;7:8. [Content Brief]

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

Ac-DNLD-CHO

2 Cited Publications

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Biologische Aktivität
- Beschreibung
- IC₅₀ & Target
Chemical Information
Publications (2)
Reinheit & Dokumentation
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Ac-DNLD-CHO

Publications Citing Use of MedChemExpress (MCE) Ac-DNLD-CHO

Alle Caspase Isoform-spezifische Produkte anzeigen