CDK5-IN-3
Based on 1 Customer Validation
CDK5-IN-3 is a CDK5 inhibitor. CDK5-IN-3 exhibits an IC50 of 0.6 μM against CDK5/p25, with a 30-fold selectivity over CDK2/CycA. CDK5-IN-3 can be used for research on CDK5-related diseases, such as autosomal dominant polycystic kidney disease.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- Reinheit : 98.99%
- CAS. Nr.: 2639542-32-6
- Formel: C22H26N4O
- Molecular Weight:362.47
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biologische Aktivität
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Chemical Information
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Lösungsmittel & Löslichkeit
- Reinheit & Dokumentation
- Verweise
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Help & FAQs
Biologische Aktivität
Beschreibung
IC50 & Target
[1]|
Cdk5/p25 0.6 nM (IC50) |
CDK2/CycA 18 nM (IC50) |
In Vitro
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS. Nr. 2639542-32-6
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Appearance Solid
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Molecular Weight 362.47
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Formel C22H26N4O
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Color Light yellow to yellow
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SMILES
C[C@@](C1=CC=C2C(C=C(NC3=CC=CC=C3)N=C2)=N1)(O)C4CCN(C)CC4
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Lösungsmittel & Löslichkeit
In Vitro:
DMSO : 10 mg/mL (27.59 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Reinheit & Dokumentation
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Data Sheet (275 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
Verweise
Complete Stock Solution Preparation Table
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.7588 mL | 13.7942 mL | 27.5885 mL | 68.9712 mL |
| 5 mM | 0.5518 mL | 2.7588 mL | 5.5177 mL | 13.7942 mL | |
| 10 mM | 0.2759 mL | 1.3794 mL | 2.7588 mL | 6.8971 mL | |
| 15 mM | 0.1839 mL | 0.9196 mL | 1.8392 mL | 4.5981 mL | |
| 20 mM | 0.1379 mL | 0.6897 mL | 1.3794 mL | 3.4486 mL | |
| 25 mM | 0.1104 mL | 0.5518 mL | 1.1035 mL | 2.7588 mL |
CDK5-IN-3 Related Classifications
HY-145694 Related Classifications
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