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Art. -Nr.: HY-187016

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CDK9 ligand-7

CDK9 ligand-7 is a CDK9 ligand. CDK9 ligand-7 can serve as a target protein ligand for the synthesis of PROTAC CDK9 degraders, such as CP-07 (HY-149495). CDK9 ligand-7 can be used in prostate cancer research.

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CAS. Nr.: 3052935-75-5
Formel: C₂₆H₂₉N₃O₄
Molecular Weight:447.53

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

CDK9 ligand-7 Chemical Structure

CAS. Nr.: 3052935-75-5

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biologische Aktivität
- Beschreibung
- IC₅₀ & Target
- Cellular Effect
Chemical Information
Reinheit & Dokumentation
Verweise
Calculators
Help & FAQs
Classifications
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Biologische Aktivität

Beschreibung

IC₅₀ & Target

^[1]

CDK9

Alle CDK Isoform-spezifische Produkte anzeigen :

Cellular Effect

Cell Line	Type	Value	Description	References
MV4-11	IC₅₀	0.13 μM Compound: 21d	Antiproliferative activity against human MV4-11 cells assessed as reduction in cell viability measured after 72 hrs Antiproliferative activity against human MV4-11 cells assessed as reduction in cell viability measured after 72 hrs	[PMID: 37572539]

Chemical Information

CAS. Nr. 3052935-75-5
Molecular Weight 447.53
Formel C₂₆H₂₉N₃O₄
SMILES

COC1=CC(O)=C(C(C=C(C2=CC=C(N3CCNCC3)C=C2)O4)=O)C4=C1C5=CCN(C)CC5
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Handling Instructions (2659 KB)

Verweise

[1]. Wu T, et al. Discovery of novel flavonoid-based CDK9 degraders for prostate cancer treatment via a PROTAC strategy. Eur J Med Chem. 2023 Nov 15;260:115774. [Content Brief]

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

Minimum order quantity

100 mg

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- IC₅₀ & Target
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CDK9 ligand-7

Alle CDK Isoform-spezifische Produkte anzeigen

Biologische Aktivität

Beschreibung

IC50 & Target

Cellular Effect

Chemical Information

Reinheit & Dokumentation

Verweise

Calculators

Help & FAQs

CDK9 ligand-7 Related Classifications

HY-187016 Related Classifications

Bioz

Keywords

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