DC_C66
DC_C66 is a cell-permeable, selective coactivator associated arginine methyltransferase 1 (CARM1) inhibitor with an IC50 of 1.8 μM. DC_C66 has a good selectivity for CARM1 against PRMT1 (IC50=21 μM), PRMT6 (IC50= 47μM), and PRMT5.
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- CAS. Nr.: 108181-00-6
- Formel: C28H22NO2+
- Molecular Weight:404.48
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
IC50: 1.8 μM (CARM1)[1]
DC_C66 (6.25-100 μM; 24-72 hours) exhibits antiproliferation activity in several CARM1-associated cancer cell lines[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:HELA, K562, MCF7 cells
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Concentration:6.25, 12.5, 25, 50, 100 μM
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Incubation Time:24, 48, 72 hours
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Result:Inhibits proliferation of cancer cells in a time-dependent and dose-dependent manner in HELA, K562, and MCF7 cells.
Chemical Information
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CAS. Nr. 108181-00-6
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Molecular Weight 404.48
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Formel C28H22NO2+
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SMILES
O=C(OCC)C1=[N+]2C(C(C=CC=C3)=C3CC2)=CC4=C1C(C=CC=C5)=C5C6=C4C=CC=C6
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
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