BAHD1 - bromo adjacent homology domain containing 1 Gene

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 22893

About BAHD1

Cytogenetic location: 15q15.1 Genomic coordinates (GRCh38): 15:40,437,452-40,468,236 (from NCBI)

This gene has 4 transcripts (splice variants), 269 orthologues and 2 paralogues. Ubiquitous expression in testis (RPKM 12.0), ovary (RPKM 8.8) and 25 other tissues.

Summary

Enables chromatin binding activity. Involved in heterochromatin assembly and negative regulation of transcription, DNA-templated. Located in nucleoplasm. Part of chromatin silencing complex. [provided by Alliance of Genome Resources, Apr 2022]

BAHD1 Products (3)

mRNA Protein Name
NM_001301132.2 NP_001288061.1 bromo adjacent homology domain-containing 1 protein isoform b
NM_001411044.1 NP_001397973.1 bromo adjacent homology domain-containing 1 protein isoform c
NM_014952.5 NP_055767.3 bromo adjacent homology domain-containing 1 protein isoform a

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Verweise Source
enables chromatin binding IDA
IDA: Inferred from direct assay
19666599 GOA
enables protein binding IPI
IPI: Inferred from physical interaction
16189514 GOA
Biological Process GO Annotation Evidence Verweise Source
involved in heterochromatin formation IMP
IMP: Inferred from mutant phenotype
19666599 GOA
involved in negative regulation of DNA-templated transcription IMP
IMP: Inferred from mutant phenotype
19666599 GOA
Cellular Component GO Annotation Evidence Verweise Source
part of chromatin silencing complex IDA
IDA: Inferred from direct assay
19666599 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

BAHD1 Protein Structure

BAH

BAH: BAH domain (624 - 773)

  • 0
  • 200
  • 400
  • 600
  • 780 a.a.
Protein Preferred Names Protein Names

bromo adjacent homology domain-containing 1 protein

  • BAH domain-containing protein 1

BAHD1 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Verweise
Intra
BAHD1 Q8TBE0 KRT40 Homo sapiens Q6A162
Y2H Prey Pooling
25416956
Intra
BAHD1 Q8TBE0 KRTAP10-8 Homo sapiens P60410
Y2H Array
32296183
Intra
BAHD1 Q8TBE0 KRTAP10-8 Homo sapiens P60410
Y2H Prey Pooling
32296183
Intra
BAHD1 Q8TBE0 KRTAP10-7 Homo sapiens P60409
Validated Y2H
25416956
Intra
BAHD1 Q8TBE0 KRTAP10-7 Homo sapiens P60409
Y2H Prey Pooling
25416956
Intra
BAHD1 Q8TBE0 MID2 Homo sapiens Q9UJV3-2
Y2H Array
32296183
Intra
BAHD1 Q8TBE0 MID2 Homo sapiens Q9UJV3-2
Y2H Prey Pooling
32296183
Intra
BAHD1 Q8TBE0 MID2 Homo sapiens Q9UJV3-2
Validated Y2H
32296183
Intra
BAHD1 Q8TBE0 FKBP1A Homo sapiens Q0VDC6
Validated Y2H
32814053
Intra
BAHD1 Q8TBE0 FKBP1A Homo sapiens Q0VDC6
Y2H Array
32814053
Intra
BAHD1 Q8TBE0 FKBP1A Homo sapiens Q0VDC6
Y2H Pooling
32814053
Intra
BAHD1 Q8TBE0 KRTAP19-7 Homo sapiens Q3SYF9
Y2H Prey Pooling
32296183
Intra
BAHD1 Q8TBE0 KRTAP19-7 Homo sapiens Q3SYF9
Y2H Array
32296183
Intra
BAHD1 Q8TBE0 EIF2S3 Homo sapiens P41091
Y2H Array
32814053
Intra
BAHD1 Q8TBE0 EIF2S3 Homo sapiens P41091
Y2H Pooling
32814053
Intra
BAHD1 Q8TBE0 EIF2S3 Homo sapiens P41091
Validated Y2H
32814053
Intra
BAHD1 Q8TBE0 GTF3C3 Homo sapiens Q9Y5Q9
Validated Y2H
32814053
Intra
BAHD1 Q8TBE0 GTF3C3 Homo sapiens Q9Y5Q9
Y2H Pooling
32814053
Intra
BAHD1 Q8TBE0 GTF3C3 Homo sapiens Q9Y5Q9
Y2H Array
32814053
Intra
BAHD1 Q8TBE0 BAG6 Homo sapiens P46379-2
Validated Y2H
32814053
Intra
BAHD1 Q8TBE0 BAG6 Homo sapiens P46379-2
Y2H Pooling
32814053
Intra
BAHD1 Q8TBE0 BAG6 Homo sapiens P46379-2
Y2H Array
32814053
Intra
BAHD1 Q8TBE0 ZNF526 Homo sapiens Q8TF50
Y2H Prey Pooling
32296183
Intra
BAHD1 Q8TBE0 ZNF526 Homo sapiens Q8TF50
Y2H Array
32296183
Intra
BAHD1 Q8TBE0 ZNF526 Homo sapiens Q8TF50
Validated Y2H
32296183
Intra
BAHD1 Q8TBE0 TLE5 Homo sapiens Q08117-2
Y2H Array
32296183
Intra
BAHD1 Q8TBE0 TLE5 Homo sapiens Q08117-2
Y2H Prey Pooling
32296183
Intra
BAHD1 Q8TBE0 ATN1 Homo sapiens Q86V38
Validated Y2H
32814053
Intra
BAHD1 Q8TBE0 ATN1 Homo sapiens Q86V38
Y2H Array
32814053
Intra
BAHD1 Q8TBE0 ATN1 Homo sapiens Q86V38
Y2H Pooling
32814053
Intra
BAHD1 Q8TBE0 ZNF837 Homo sapiens Q96EG3
Y2H Prey Pooling
32296183
Intra
BAHD1 Q8TBE0 ZNF837 Homo sapiens Q96EG3
Validated Y2H
32296183
Intra
BAHD1 Q8TBE0 ZNF837 Homo sapiens Q96EG3
Y2H Array
32296183
Intra
BAHD1 Q8TBE0 ZNF317 Homo sapiens Q96PQ6
Y2H Prey Pooling
32296183
Intra
BAHD1 Q8TBE0 ZNF317 Homo sapiens Q96PQ6
Validated Y2H
32296183
Intra
BAHD1 Q8TBE0 ZNF317 Homo sapiens Q96PQ6
Y2H Array
32296183
Intra
BAHD1 Q8TBE0 KRTAP6-1 Homo sapiens Q3LI64
Y2H Prey Pooling
32296183
Intra
BAHD1 Q8TBE0 KRTAP6-1 Homo sapiens Q3LI64
Y2H Array
32296183
Intra
BAHD1 Q8TBE0 KRTAP19-1 Homo sapiens Q8IUB9
Y2H Prey Pooling
32296183
Intra
BAHD1 Q8TBE0 KRTAP19-1 Homo sapiens Q8IUB9
Y2H Array
32296183
Intra
BAHD1 Q8TBE0 KRTAP2-4 Homo sapiens Q9BYR9
Validated Y2H
32296183
Intra
BAHD1 Q8TBE0 KRTAP2-4 Homo sapiens Q9BYR9
Y2H Prey Pooling
32296183
Intra
BAHD1 Q8TBE0 KRTAP2-4 Homo sapiens Q9BYR9
Y2H Array
32296183
Intra
BAHD1 Q8TBE0 BACH2 Homo sapiens Q9BYV9
Y2H Array
32296183
Intra
BAHD1 Q8TBE0 BACH2 Homo sapiens Q9BYV9
Y2H Prey Pooling
32296183
Intra
BAHD1 Q8TBE0 BACH2 Homo sapiens Q9BYV9
Validated Y2H
32296183
Intra
BAHD1 Q8TBE0 ZNF275 Homo sapiens Q9NSD4
Y2H Prey Pooling
32296183
Intra
BAHD1 Q8TBE0 ZNF275 Homo sapiens Q9NSD4
Validated Y2H
32296183
Intra
BAHD1 Q8TBE0 ZNF275 Homo sapiens Q9NSD4
Y2H Array
32296183
Intra
BAHD1 Q8TBE0 COL26A1 Homo sapiens Q96A83-2
Validated Y2H
32814053
Intra
BAHD1 Q8TBE0 COL26A1 Homo sapiens Q96A83-2
Y2H Array
32814053
Intra
BAHD1 Q8TBE0 COL26A1 Homo sapiens Q96A83-2
Y2H Pooling
32814053
Intra
BAHD1 Q8TBE0 KLK6 Homo sapiens Q92876
Y2H Array
32814053
Intra
BAHD1 Q8TBE0 KLK6 Homo sapiens Q92876
Y2H Pooling
32814053
Intra
BAHD1 Q8TBE0 KLK6 Homo sapiens Q92876
Validated Y2H
32814053
Intra
BAHD1 Q8TBE0 CHAT Homo sapiens P28329-3
Validated Y2H
32814053
Intra
BAHD1 Q8TBE0 CHAT Homo sapiens P28329-3
Y2H Pooling
32814053
Intra
BAHD1 Q8TBE0 CHAT Homo sapiens P28329-3
Y2H Array
32814053
Intra
BAHD1 Q8TBE0 ERN1 Homo sapiens O75460-2
Y2H Array
32814053
Intra
BAHD1 Q8TBE0 ERN1 Homo sapiens O75460-2
Validated Y2H
32814053
Intra
BAHD1 Q8TBE0 ERN1 Homo sapiens O75460-2
Y2H Pooling
32814053
Intra
BAHD1 Q8TBE0 GIPC1 Homo sapiens O14908-2
Y2H Array
32814053
Intra
BAHD1 Q8TBE0 GIPC1 Homo sapiens O14908-2
Y2H Pooling
32814053
Intra
BAHD1 Q8TBE0 GIPC1 Homo sapiens O14908-2
Validated Y2H
32814053
Intra
BAHD1 Q8TBE0 NUP58 Homo sapiens Q9BVL2
Validated Y2H
32814053
Intra
BAHD1 Q8TBE0 NUP58 Homo sapiens Q9BVL2
Y2H Array
32814053
Intra
BAHD1 Q8TBE0 NUP58 Homo sapiens Q9BVL2
Y2H Pooling
32814053
Intra
BAHD1 Q8TBE0 TGFBR2 Homo sapiens P37173
Validated Y2H
32814053
Intra
BAHD1 Q8TBE0 TGFBR2 Homo sapiens P37173
Y2H Pooling
32814053
Intra
BAHD1 Q8TBE0 TGFBR2 Homo sapiens P37173
Y2H Array
32814053
Intra
BAHD1 Q8TBE0 ZNF408 Homo sapiens Q9H9D4
Y2H Prey Pooling
32296183
Intra
BAHD1 Q8TBE0 ZNF408 Homo sapiens Q9H9D4
Y2H Array
32296183
Intra
BAHD1 Q8TBE0 ZNF408 Homo sapiens Q9H9D4
Validated Y2H
32296183
Intra
BAHD1 Q8TBE0 FGFR3 Homo sapiens P22607
Y2H Pooling
32814053
Intra
BAHD1 Q8TBE0 FGFR3 Homo sapiens P22607
Validated Y2H
32814053
Intra
BAHD1 Q8TBE0 FGFR3 Homo sapiens P22607
Y2H Array
32814053
Intra
BAHD1 Q8TBE0 SERPINH1 Homo sapiens P50454
Validated Y2H
32814053
Intra
BAHD1 Q8TBE0 SERPINH1 Homo sapiens P50454
Y2H Pooling
32814053
Intra
BAHD1 Q8TBE0 SERPINH1 Homo sapiens P50454
Y2H Array
32814053
Intra
BAHD1 Q8TBE0 GSN Homo sapiens P06396
Y2H Array
32814053
Intra
BAHD1 Q8TBE0 GSN Homo sapiens P06396
Y2H Pooling
32814053
Intra
BAHD1 Q8TBE0 GSN Homo sapiens P06396
Validated Y2H
32814053
Intra
BAHD1 Q8TBE0 TRAF2 Homo sapiens Q12933
Y2H Array
32296183
Intra
BAHD1 Q8TBE0 TRAF2 Homo sapiens Q12933
Y2H Prey Pooling
32296183
Intra
BAHD1 Q8TBE0 KPNA3 Homo sapiens O00505
Y2H Prey Pooling
32296183
Intra
BAHD1 Q8TBE0 KPNA3 Homo sapiens O00505
Y2H Array
32296183
Intra
BAHD1 Q8TBE0 TRAF4 Homo sapiens Q9BUZ4
Validated Y2H
25416956
Intra
BAHD1 Q8TBE0 TRAF4 Homo sapiens Q9BUZ4
Y2H Prey Pooling
32296183
Intra
BAHD1 Q8TBE0 TRAF4 Homo sapiens Q9BUZ4
Validated Y2H
32296183
Intra
BAHD1 Q8TBE0 TRAF4 Homo sapiens Q9BUZ4
Y2H Array
25416956
Intra
BAHD1 Q8TBE0 TRAF4 Homo sapiens Q9BUZ4
Y2H Array
32296183
Intra
BAHD1 Q8TBE0 CARD10 Homo sapiens Q9BWT7
Y2H Array
32296183
Intra
BAHD1 Q8TBE0 CARD10 Homo sapiens Q9BWT7
Y2H Prey Pooling
32296183
Intra
BAHD1 Q8TBE0 CARD10 Homo sapiens Q9BWT7
Validated Y2H
32296183
Intra
BAHD1 Q8TBE0 CYSRT1 Homo sapiens A8MQ03
Y2H Prey Pooling
32296183
Intra
BAHD1 Q8TBE0 CYSRT1 Homo sapiens A8MQ03
Y2H Array
32296183
Intra
BAHD1 Q8TBE0 PRDM14 Homo sapiens Q9GZV8
Y2H Prey Pooling
32296183
Intra
BAHD1 Q8TBE0 PRDM14 Homo sapiens Q9GZV8
Validated Y2H
32296183
Intra
BAHD1 Q8TBE0 PRDM14 Homo sapiens Q9GZV8
Y2H Array
32296183
Intra
BAHD1 Q8TBE0 SPRED1 Homo sapiens Q7Z699
Y2H Array
32814053
Intra
BAHD1 Q8TBE0 SPRED1 Homo sapiens Q7Z699
Y2H Pooling
32814053
Intra
BAHD1 Q8TBE0 SPRED1 Homo sapiens Q7Z699
Validated Y2H
32814053
Intra
BAHD1 Q8TBE0 ZRANB1 Homo sapiens Q9UGI0
Validated Y2H
32296183
Intra
BAHD1 Q8TBE0 ZRANB1 Homo sapiens Q9UGI0
Y2H Prey Pooling
32296183
Intra
BAHD1 Q8TBE0 GOLGA6L9 Homo sapiens A6NEM1
Y2H Array
32296183
Intra
BAHD1 Q8TBE0 GOLGA6L9 Homo sapiens A6NEM1
Y2H Prey Pooling
32296183
Intra
BAHD1 Q8TBE0 GOLGA2 Homo sapiens Q08379
Validated Y2H
25416956
Intra
BAHD1 Q8TBE0 KHDRBS3 Homo sapiens O75525
Y2H Array
25416956
Intra
BAHD1 Q8TBE0 MDFI Homo sapiens Q99750
Validated Y2H
32296183
Intra
BAHD1 Q8TBE0 MDFI Homo sapiens Q99750
Y2H Array
32296183
Intra
BAHD1 Q8TBE0 MDFI Homo sapiens Q99750
Validated Y2H
25416956
Intra
BAHD1 Q8TBE0 MDFI Homo sapiens Q99750
Y2H Prey Pooling
32296183
Intra
BAHD1 Q8TBE0 CALCOCO2 Homo sapiens Q13137
Y2H Array
25416956
Intra
BAHD1 Q8TBE0 DVL3 Homo sapiens Q92997
Validated Y2H
32296183
Intra
BAHD1 Q8TBE0 DVL3 Homo sapiens Q92997
Y2H Array
32296183
Intra
BAHD1 Q8TBE0 DVL3 Homo sapiens Q92997
Y2H Prey Pooling
32296183
Intra
BAHD1 Q8TBE0 HOXA1 Homo sapiens P49639
Y2H Prey Pooling
32296183
Intra
BAHD1 Q8TBE0 LZTS2 Homo sapiens Q9BRK4
Y2H Prey Pooling
25416956
Intra
BAHD1 Q8TBE0 LZTS2 Homo sapiens Q9BRK4
Y2H Prey Pooling
32296183
Intra
BAHD1 Q8TBE0 LZTS2 Homo sapiens Q9BRK4
Y2H
21516116
Intra
BAHD1 Q8TBE0 LZTS2 Homo sapiens Q9BRK4
Validated Y2H
32296183
Intra
BAHD1 Q8TBE0 LZTS2 Homo sapiens Q9BRK4
Validated Y2H
25416956
Intra
BAHD1 Q8TBE0 LZTS2 Homo sapiens Q9BRK4
Y2H Array
32296183
Intra
BAHD1 Q8TBE0 KHDRBS2 Homo sapiens Q5VWX1
Y2H Prey Pooling
32296183
Intra
BAHD1 Q8TBE0 KHDRBS2 Homo sapiens Q5VWX1
Y2H Array
32296183
Intra
BAHD1 Q8TBE0 GFAP Homo sapiens P14136
Validated Y2H
32814053
Intra
BAHD1 Q8TBE0 GFAP Homo sapiens P14136
Y2H Array
32814053
Intra
BAHD1 Q8TBE0 GFAP Homo sapiens P14136
Y2H Pooling
32814053
Intra
BAHD1 Q8TBE0 M1AP Homo sapiens Q8TC57
Validated Y2H
32296183
Intra
BAHD1 Q8TBE0 DR1 Homo sapiens Q01658
Validated Y2H
32814053
Intra
BAHD1 Q8TBE0 DR1 Homo sapiens Q01658
Y2H Array
32814053
Intra
BAHD1 Q8TBE0 DR1 Homo sapiens Q01658
Y2H Pooling
32814053
Intra
BAHD1 Q8TBE0 CBX1 Homo sapiens P83916
Y2H Prey Pooling
32296183
Intra
BAHD1 Q8TBE0 CBX1 Homo sapiens P83916
Y2H Array
32296183
Intra
BAHD1 Q8TBE0 CBX5 Homo sapiens P45973
Y2H Pooling
32814053
Intra
BAHD1 Q8TBE0 CBX5 Homo sapiens P45973
Validated Y2H
32814053
Intra
BAHD1 Q8TBE0 CBX5 Homo sapiens P45973
Y2H Array
32814053
Intra
BAHD1 Q8TBE0 PICK1 Homo sapiens Q9NRD5
Validated Y2H
32296183
Intra
BAHD1 Q8TBE0 PICK1 Homo sapiens Q9NRD5
Y2H Array
32296183
Intra
BAHD1 Q8TBE0 PICK1 Homo sapiens Q9NRD5
Y2H Prey Pooling
32296183
Intra
BAHD1 Q8TBE0 LASP1 Homo sapiens Q14847-2
Y2H Array
32296183
Intra
BAHD1 Q8TBE0 LASP1 Homo sapiens Q14847-2
Y2H Prey Pooling
32296183
Intra
BAHD1 Q8TBE0 ARID5A Homo sapiens Q03989
Y2H Prey Pooling
32296183
Intra
BAHD1 Q8TBE0 ARID5A Homo sapiens Q03989
Y2H Array
32296183
Intra
BAHD1 Q8TBE0 TNS2 Homo sapiens Q63HR2
Y2H Prey Pooling
32296183
Intra
BAHD1 Q8TBE0 TNS2 Homo sapiens Q63HR2
Y2H Array
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases Alias
Human Granulocytic Anaplasmosis

  • Human Granulocytic Ehrlichiosis

  • Hge

  • Human Ehrlichial Infection, Human Granulocytic Type

  • Human Anaplasmosis Due To Anaplasma Phagocytophilum
Listeriosis

  • Listeria Infection

  • Infection By Listeria Monocytogenes

  • Listeria Monocytogenes Infection

  • Listeria Infections

  • Listerial Foodborne Infection

  • Circling Disease

  • Infection Due To Listeria Monocytogenes

  • Listerellosis
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Art. -Nr. Produktname
Wirkung
Reinheit
Rare Diseases
HY-RS01352 BAHD1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta BAHD1 VGNC VGNC:70150
Bos taurus BAHD1 VGNC VGNC:26411
Felis catus BAHD1 VGNC VGNC:60070
Rattus norvegicus BAHD1 RGD RGD:1563127
Mus musculus BAHD1 MGD MGI:2139371
Canis familiaris BAHD1 VGNC VGNC:38370
Others BAHD1 NCBI