HDAC3-IN-7
HDAC3-IN-7 (Compound 8ae) is a selective HDAC3 inhibitor with an IC50 value of 311 nM. HDAC3-IN-7 degrades PD-L1 through the lysosome pathway mediated by Cathepsin B, exerting activities such as inhibiting tumor cell proliferation, migration, and invasion. HDAC3-IN-7 is promising for research of cancers.
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- CAS. Nr.: 3104610-92-3
- Formel: C25H37N5O4S
- Molecular Weight:503.66
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biologische Aktivität
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HDAC3 311 nM (IC50) |
Chemical Information
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CAS. Nr. 3104610-92-3
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Molecular Weight 503.66
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Formel C25H37N5O4S
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SMILES
O=C(NNCCC)CCCCCCNC(C1=CN=C(C2=CC=C(NC(OC(C)(C)C)=O)C=C2)S1)=O
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)