HVF18-a3-d
HVF18-a3-d is an antimicrobial peptide. HVF18-a3-d reduces NO production. HVF18-a3-d inhibits the production of TNF-α and IL-6, reduces ROS production, and suppresses the TLR4 signaling pathway, as well as LPS-induced phosphorylation of ERK, JNK, and p38 MAPK. HVF18-a3-d exhibits antimicrobial activity against a variety of bacteria by disrupting their outer and inner membranes. HVF18-a3-d protects mice from fatal septic shock induced by Acinetobacter baumannii resistant to Carbapenem. HVF18-a3-d shows anti-inflammatory and antioxidant effects.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- Formel: C111H185N31O18
- Molecular Weight:2241.85
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biologische Aktivität
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Chemical Information
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- Reinheit & Dokumentation
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Help & FAQs
Biologische Aktivität
Beschreibung
IC50 & Target
[1]|
IL-6 |
TLR4 |
Chemical Information
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Molecular Weight 2241.85
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Formel C111H185N31O18
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Sequence
d-{Gly-Val-Phe-Arg-Leu-Lys-Lys-Trp-Leu-Lys-Lys-Val-Leu-Lys-Lys-Trp-Gly-Lys}-NH2
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Sequence Shortening
d-{GVFRLKKWLKKVLKKWGK}-NH2
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
HVF18-a3-d Related Classifications
HY-P11250 Related Classifications
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