Leuxinostat
Leuxinostat is an inhibitor for HDAC with IC50 of 30 nM for hHDAC6. Leuxinostat inhibits the proliferation of cells THP1, K562, U937 and MEK1, induces apoptosis in leukemia cells NB4 and MOLT-4. Leuxinostat inhibits the expansion of hematopoietic stem cells and exhibits antileukemic activity in zebrafish models.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- Formel: C18H20N4O4
- Molecular Weight:356.38
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biologische Aktivität
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Chemical Information
- Reinheit & Dokumentation
- Verweise
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Help & FAQs
Biologische Aktivität
|
hHDAC6 0.03 μM (IC50) |
hHDAC1 1.203 μM (IC50) |
hHDAC8 2.446 μM (IC50) |
hHDAC3 2.858 μM (IC50) |
hHDAC10 4.811 μM (IC50) |
hHDAC11 5.57 μM (IC50) |
Chemical Information
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Molecular Weight 356.38
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Formel C18H20N4O4
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SMILES
O=C(NO)C(C=C1)=CC=C1CN2CCN(C3=CC=C([N+]([O-])=O)C=C3)CC2
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Leuxinostat Related Classifications
HY-162658 Related Classifications
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