PRMT5-IN-28
PRMT5-IN-28 (compound 36) is an inhibitor of protein arginine methyltransferase 5 (PRMT5) enzyme. Protein arginine methylation is a common post-translational modification involved in gene transcription, mRNA splicing, DNA repair, protein cellular localization, cell fate determination and signal transduction, etc. Abnormal PRMT5 can promote cancer cell proliferation, resist apoptosis, enhance invasion and metastasis, and affect immune escape.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- CAS. Nr.: 2242753-66-6
- Formel: C18H19ClN4O5
- Molecular Weight:406.82
-
Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
Alle Histone Methyltransferase Isoform-spezifische Produkte anzeigen
More
Biologische Aktivität
Beschreibung
IC50 & Target
[1]|
PRMT5 |
Chemical Information
-
CAS. Nr. 2242753-66-6
-
Molecular Weight 406.82
-
Formel C18H19ClN4O5
-
SMILES
O[C@H]([C@@H]1O)[C@@H](O[C@]1([H])[C@@H](C(C=C2)=CC=C2Cl)O)N3C(NC=N/C4=N\OC)=C4C=C3
-
Versand
Room temperature in continental US; may vary elsewhere.
-
Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)