Satratoxin G
Based on 1 Customer Validation
Satratoxin G is a large cyclic mucor toxin. Satratoxin G induces apoptosis by activation of caspase .
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- Reinheit: 99.5%
- CAS. Nr.: 53126-63-9
- Formel: C29H36O10
- Molecular Weight:544.59
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Speicherung:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biologische Aktivität
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Chemical Information
- Reinheit & Dokumentation
- Verweise
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Help & FAQs
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Biologische Aktivität
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Pathogen-free female C57Bl/6 mice [2]
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Dosage:500 μg/kg
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Administration:intranasal instillation
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Result:Up-regulated the proapoptotic genes Fas, FasL, p75NGFR, p53, Bax, caspase-3, and CAD.
Increased expression of mRNAs for the cytokines TNF-α, IL-1α, IL-1β, and IL-6 as well as the chemokine MIP-2.
Chemical Information
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CAS. Nr. 53126-63-9
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Appearance Solid
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Molecular Weight 544.59
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Formel C29H36O10
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Color White to off-white
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SMILES
CC1=C[C@]2([H])[C@]([C@]3(C)[C@@]4(OC4)[C@](C[C@H]3OC(/C=C\C=C\[C@@]5(C(O)C)[C@H](O)[C@@]6(C7O6)CCO5)=O)([H])O2)(COC7=O)CC1
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Structure Classification
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Initial Source
aflatoxin
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Reinheit & Dokumentation
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Data Sheet (279 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
Verweise
[1]. Nagase M, et al. Molecular mechanism of satratoxin-induced apoptosis in HL-60 cells: activation of caspase-8 and caspase-9 is involved in activation of caspase-3. Immunol Lett. 2002 Oct 21;84(1):23-7. [Content Brief]
[2]. Islam Z, et al. Satratoxin G from the black mold Stachybotrys chartarum evokes olfactory sensory neuron loss and inflammation in the murine nose and brain. Environ Health Perspect. 2006 Jul;114(7):1099-107. [Content Brief]
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Satratoxin G Related Classifications
HY-130476 Related Classifications
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