SNAP8719 free base
SNAP8719 free base is a selective α1D-adrenoceptor antagonist (pKi = 8.89). SNAP8719 free base shows affinity for the dopamine D2-, 5-HT1A-, and the human clonal α2a-adrenoceptor, with pKi values of 5.98, 6.47, and <5.0, respectively. SNAP8719 free base causes a concentration-dependent increase in the twitch response.
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- CAS. Nr.: 255893-38-0
- Formel: C22H28F3N3O2
- Molecular Weight:423.47
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
Beschreibung
IC50 & Target
[1]|
Alpha-1D adrenergic receptor 8.89 (pKi) |
D2 Receptor 5.98 (pKi) |
5-HT1A Receptor 6.47 (pKi) |
Alpha-2A adrenergic receptor <5.0 (pKi) |
Chemical Information
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CAS. Nr. 255893-38-0
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Molecular Weight 423.47
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Formel C22H28F3N3O2
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SMILES
O=C(N([C@H](C)CN1CCN(C2=CC(F)=C(F)C=C2F)CC1)C(C3)=O)CC43CCCC4
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
SNAP8719 free base Related Classifications
HY-123514 Related Classifications
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