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Cat. No.: HY-164462

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BHA536

BHA536 is an orally active selective inhibitor for PKCα/β and NF-kB signaling pathway. BHA536 inhibits the proliferation of CD79-mutated ABC DLBCL cell, arrests cell cycle at G1 phase, and induces apoptosis in TMD8 cell. BHA536 exhibits antitumor efficacy in mice.

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CAS No.: 919992-85-1
Formule: C₃₀H₃₀ClN₃O₅
Masse moléculaire:548.03

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Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (272 KB)

BHA536 Chemical Structure

CAS No.: 919992-85-1

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique

Description

Voir tous les produits spécifiques à Isoform PKC :

Voir tous les produits spécifiques à Isoform NF-κB :

Chemical Information

CAS No. 919992-85-1
Masse moléculaire 548.03
Formule C₃₀H₃₀ClN₃O₅
SMILES

CN(C)CC1=CC2=C(C=C1)C=CC(Cl)=C2C3=C(C4=CNC5=C4C=CC=C5OCCOCCOC)C(NC3=O)=O
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (272 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Naylor TL, et al., Protein kinase C inhibitor sotrastaurin selectively inhibits the growth of CD79 mutant diffuse large B-cell lymphomas. Cancer Res. 2011 Apr 1;71(7):2643-53. [Content Brief]

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How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Activité biologique
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Chemical Information
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BHA536

Voir tous les produits spécifiques à Isoform PKC

Voir tous les produits spécifiques à Isoform NF-κB

Activité biologique

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

BHA536 Related Classifications

HY-164462 Related Classifications