Lambertellin
Lambertellin is an effective antibiotic that can be used as a bactericide and as a fungicide. Lambertellin exerts its anti-inflammatory effect in LPS (HY-D1056)-stimulated RAW 264.7 macrophage cells by modulating the activation of the MAPK and NF-κB signaling pathways.
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- CAS No.: 28980-51-0
- Formule: C14H8O5
- Masse moléculaire:256.21
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
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- Pureté et documentation
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Activité biologique
Description
In Vitro
In lipopolysaccharide (LPS)-stimulated RAW 264.7 macrophage cells, Lambertellin exhibits promising inhibitory activity against nitric oxide (NO) production with an IC50 value of 3.19 µM, and it significantly inhibits the expression of inducible NO synthase (iNOS) and cyclooxygenase 2 (COX-2). Lambertellin also decreases the expression of pro-inflammatory cytokines IL-6 and IL-1β[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 28980-51-0
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Masse moléculaire 256.21
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Formule C14H8O5
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SMILES
O=C1OC(C(C2=C3C=CC=C2O)=O)=C(C=C1C)C3=O
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Structure Classification
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Initial Source
Lambertella sp.
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Lambertellin Related Classifications
HY-124508 Related Classifications
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