Cosdosiran sodium
Based on 1 publication(s) in Google Scholar
Cosdosiran sodium is a chemically modified siRNA designed to temporarily inhibit expression of the caspase 2 protein and can be used for the study of nonarteritic anterior ischemic optic neuropathy and other optic neuropathies such as glaucoma that result in the death of retinal ganglion cells.
For research use only. We do not sell to patients.
- Purity: 98.48%
- Molecular Weight:12388.68 (free acid)
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Storage:
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Publications Citing Use of MedChemExpress (MCE) Cosdosiran sodium
MoreAll Caspase Isoforms
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Biological Activity
Chemical Information
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Appearance Solid
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Molecular Weight 12388.68 (free acid)
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Color White to off-white
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SMILES
[Cosdosiran (sodium)]
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Synonyms
QPI-1007 sodium
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Publications (1)
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Journal Impact Factor
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Most Recent
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J Vis Exp
Assessing Microglial Phagocytosis of Myelin Debris in vitro Under Repeated Magnetic Stimulation. [Abstract]2025 Jun 17:(220). PMID: 40622958
Solvent & Solubility
H2O : ≥ 50 mg/mL
* "≥" means soluble, but saturation unknown.
Purity & Documentation
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Data Sheet (267 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2242 KB)
References
[1]. Solano EC, Kornbrust DJ, Beaudry A, Foy JW, Schneider DJ, Thompson JD. Toxicological and pharmacokinetic properties of QPI-1007, a chemically modified synthetic siRNA targeting caspase 2 mRNA, following intravitreal injection. Nucleic Acid Ther. 2014;24(4):258-266. doi:10.1089/nat.2014.0489 [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)