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Cat. No.: HY-169350

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EA-B2L

EA-B2L is a potent degrader of glutathione S-transferase (GSTP), with the DC₅₀ of 48 μM. EA-B2L is a kind of Boc2Lys-linked Ethacrynic acid (HY-B1640). EA-B2L plays an important role in cancer research.

For research use only. We do not sell to patients.

CAS No.: 1354444-72-6
Formula: C₃₅H₅₄Cl₂N₄O₈
Molecular Weight:729.73

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (262 KB)

EA-B2L Chemical Structure

CAS No.: 1354444-72-6

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Sample (0.1mg)

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

Chemical Information

CAS No. 1354444-72-6
Molecular Weight 729.73
Formula C₃₅H₅₄Cl₂N₄O₈
SMILES

CCC(C(C1=C(C(Cl)=C(C=C1)OCC(NCCCCCCNC([C@H](CCCCNC(OC(C)(C)C)=O)NC(OC(C)(C)C)=O)=O)=O)Cl)=O)=C
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (262 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Hui Sun, et al. Identification of Boc2Lys-Linked Ethacrynic Acid and Its Analogues As Efficient Glutathione S-Transferase Degraders. ACS Med Chem Lett. 2024 Oct 14;15(11):1852-1859 [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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