YSY01A
YSY01A is a proteasome inhibitor that can suppress cancer cell survival by inducing apoptosis (Apoptosis). Its IC50 values are 51.0 nM for HEK293T, 9.2 nM for A549, 5.2 nM for MCF-7, 8.9 nM for MGC-803, and 35.4 nM for PC-3M cells. Additionally, YSY01A eliminates constitutive STAT3 signaling by downregulating gp130 and JAK2 in human A549 lung cancer cells. YSY01A holds promise for research in the field of cancer therapy.
For research use only. We do not sell to patients.
- CAS No.: 1194235-46-5
- Formula: C29H38BN5O5
- Molecular Weight:547.45
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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IL6-beta |
JAK2 |
Stat-3 |
Chemical Information
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CAS No. 1194235-46-5
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Molecular Weight 547.45
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Formula C29H38BN5O5
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SMILES
O=C(N[C@@H](CC(C)C)C(N[C@@H](CC1=CC=C(C=CC=C2)C2=C1)C(N[C@H](B(O)O)CC(C)C)=O)=O)C3=CN=CC=N3
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)